Basic Information | |
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Species | Brachypodium distachyon |
Cazyme ID | Bradi1g24360.1 |
Family | GT47 |
Protein Properties | Length: 499 Molecular Weight: 55839.1 Isoelectric Point: 9.2288 |
Chromosome | Chromosome/Scaffold: 1 Start: 19540962 End: 19545197 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 100 | 422 | 0 |
PVKIYLYDLPSKFTYGVVRSYMSARAPPGSADAAATLPDEELRYPGHQHSAEWWLFKDLRRRGPRERPVARVDDPAEADLFYVPFFSSLSLVVNPIRPLA AANASVAAAEPAYSDEAMQDELVEWLERQPYWRRHRGRDHVFICQDPNALYRVVDRISNAVLLVSDFGRLRGDQASLVKDVILPYSHRINPFQGDVSIEA RPALLFFMGNRYRKEGGKVRDTLFQVLENEGDVIIKHGTQSRVSRRMATQGMHSSKFCLHPAGDTPSACRLFDALVSLCVPVIISDHIELPFEDVIDYSN ISIFVDTSKAVQPGFLTSMLRRV |
Full Sequence |
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Protein Sequence Length: 499 Download |
MWERGRPPPR KPRPSPLILP ASALVSPPPP RFVFPRSLFA LAARAMPSRR PSPALLLLLA 60 LALALLFLLL SPSGPSASRL SHSFASASSS YPASSPLPSP VKIYLYDLPS KFTYGVVRSY 120 MSARAPPGSA DAAATLPDEE LRYPGHQHSA EWWLFKDLRR RGPRERPVAR VDDPAEADLF 180 YVPFFSSLSL VVNPIRPLAA ANASVAAAEP AYSDEAMQDE LVEWLERQPY WRRHRGRDHV 240 FICQDPNALY RVVDRISNAV LLVSDFGRLR GDQASLVKDV ILPYSHRINP FQGDVSIEAR 300 PALLFFMGNR YRKEGGKVRD TLFQVLENEG DVIIKHGTQS RVSRRMATQG MHSSKFCLHP 360 AGDTPSACRL FDALVSLCVP VIISDHIELP FEDVIDYSNI SIFVDTSKAV QPGFLTSMLR 420 RVSSERILEY QREIKRVKHY FEYEDPNGPV NQIWHQVSMK APLIKLLINR DKRLVERATN 480 ETDCSCICST PSEISTGN* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-71 | 101 | 422 | 333 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAC55656.1 | 0 | 98 | 494 | 54 | 450 | exostosin family protein-like protein [Oryza sativa Japonica Group] |
GenBank | EEC82282.1 | 0 | 105 | 494 | 1 | 390 | hypothetical protein OsI_26516 [Oryza sativa Indica Group] |
GenBank | EEE67431.1 | 0 | 1 | 494 | 1 | 497 | hypothetical protein OsJ_24780 [Oryza sativa Japonica Group] |
RefSeq | NP_001060019.1 | 0 | 1 | 494 | 1 | 497 | Os07g0567000 [Oryza sativa (japonica cultivar-group)] |
RefSeq | XP_002460871.1 | 0 | 44 | 498 | 43 | 500 | hypothetical protein SORBIDRAFT_02g036640 [Sorghum bicolor] |