| Basic Information | |
|---|---|
| Species | Brachypodium distachyon |
| Cazyme ID | Bradi1g29622.1 |
| Family | GT48 |
| Protein Properties | Length: 1966 Molecular Weight: 226117 Isoelectric Point: 9.3271 |
| Chromosome | Chromosome/Scaffold: 1 Start: 25162279 End: 25175875 |
| Description | glucan synthase-like 12 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT48 | 1073 | 1821 | 0 |
| VPTNLDARRRISFFANSLFMEMPNAPEVRNMLPFSVLTPYYKEDVLFSLHNLEEPNEDGVSILFYLQKIYPDEWKNFLERVDRKTEEEVREDETLEDELR LWASYRGQTLTRTVRGMMYYRKALELQGFLDMAKDDDLMKGYRATELMSEESPLMTQCKAIADMKFTYVVSCQQYGIQKRSNDPCAHDILRLMTTYPSLR VAYIDEVEAPSQDRIKKIDKVYYSVLVKASVTKPNDPGQSLDQVIYKIKLPGNAILGEGKPENQNHAIIFTRGECLQTIDMNQEHYMEEALKMRNLLQEF LEKHDGVRYPSILGVREHIFTGSVSSLAWFMSNQETSFVTIGQRVLANPLRVRFHYGHPDIFDRLFHLTRGGISKASKIINLSEDIFAGFNSTLRGGNVT HHEYMQVGKGRDVGLNQISLFEAKIANGNGEQTLSRDIYRLGHRFDFFRMLSCYYTTIGFYFSTMITVWTVYVFLYGRLYLVLSGLDEALATGKRFVHNS PLQVALASESFVQLGFLMALPMMMEIGLERGFRTALSDFVLMQLQLASVFFTFSLGTKTHYYGRTLLHGGAEYRATGRGFVVFHAKFAENYRLYSRSHFV KGIELMILLVVYEIFGQSYRGAITYIFITVSMWFMVGTWLFAPFLFNPSGFEWQKIVDDWTDWNKWIHNRGGIGVAPEKSWESWWDKEQGPLRHSGKRGT VVEILLALRFFIYQYGLVYHLNITKQYNKSVLVYGISWVVIFSMLLVMK | |||
| Full Sequence |
|---|
| Protein Sequence Length: 1966 Download |
| MAAPGRRADF SSSSAQSPGP SPAGASGGGG GGRRLLRTQT VGGNMGESIF DSEVVPSSLV 60 EIAPILRVAN EVEAGNPRVA YLCRFYAFEK AHRLDPNSSG RGVRQFKTAL LQRLERENDP 120 TLKGRVHQSD AREMQRFYRE YYKKYIHALQ SAADKADRAL LTKAYQTAAV LFEVLKAVNV 180 SQSVEVDQAI LDTHNKIEEK KKLYVPYNIL PLDPESTDEA IMQYPEIRAS VYALRNTRGL 240 PWPKENEKKP DEKKTDKDLL DWLQAMFGFQ KDNVSNQREH LILLLANVHI RQIPKPDQQS 300 KLDDRALDAV MKRLFKNYKM WCKYLGRKSS LWLPTIQQEV QQRKLLYMGL YLLIWGEAAN 360 LRFMPECLCY IYHHMAFELY GMLAGNVSPM TGENVKPAYG GDEEAFLMKI VTPIYKVIEE 420 EAHRSKTMKS KHSHWRNYDD LNEYFWKVDC FRLGWPMRAD ADFFKTPKLA YPNRLNGEER 480 SAGSVHWMGK INFVEIRSFW HIFRSFDRMW IFLILSLQAM VIIAWNGGTP SDIFDSGVLQ 540 QVLSIFITAA VLKLGQATLD IVFGWKARTN MSFARKLRYV LKLVSAAAWV VILPVTYAYT 600 WTNPTGLART IKDWLGNGHQ PSLYILAVVV YLAPNMLASG LFLFPCIRRY LESSNFKVIT 660 FMMWWSQPRV FVGRGMHEGP FSLFKYTMFW VLLLAMKLTV SFYIEIKPLV QPTKDIMGTP 720 IRTFQWHEFF PHANNNIGVV IALWAPIILV YFMDTQIWYA VFSTLVGGIY GACRRLGEIR 780 TLGMLRYRFE SLPDAFNKWL IPSDAHKRKG FRAAFSTKPS KSPSDEQEIE KRAARFAQMW 840 NLIITSFREE DLIDNREMDL LLVPYCKDRE LNIFQWPPFL LASKIPIALD MAADSGGKDR 900 DLNKRMGSDP YFSYAIRECY ASFKNIINTL VSGQREKVVM QEIFTVVEKH INEGTLIKDL 960 HMRNLPALSK KLIELLELLQ TNKEEDKGQV VILFQDMLEV VTRDIMEDQE LGGVLDSIHG 1020 GNSRKHEGMT PLDQQDQLFT KAIKFPVVES NAWTEKIKRL QLLLTVKESA MDVPTNLDAR 1080 RRISFFANSL FMEMPNAPEV RNMLPFSVLT PYYKEDVLFS LHNLEEPNED GVSILFYLQK 1140 IYPDEWKNFL ERVDRKTEEE VREDETLEDE LRLWASYRGQ TLTRTVRGMM YYRKALELQG 1200 FLDMAKDDDL MKGYRATELM SEESPLMTQC KAIADMKFTY VVSCQQYGIQ KRSNDPCAHD 1260 ILRLMTTYPS LRVAYIDEVE APSQDRIKKI DKVYYSVLVK ASVTKPNDPG QSLDQVIYKI 1320 KLPGNAILGE GKPENQNHAI IFTRGECLQT IDMNQEHYME EALKMRNLLQ EFLEKHDGVR 1380 YPSILGVREH IFTGSVSSLA WFMSNQETSF VTIGQRVLAN PLRVRFHYGH PDIFDRLFHL 1440 TRGGISKASK IINLSEDIFA GFNSTLRGGN VTHHEYMQVG KGRDVGLNQI SLFEAKIANG 1500 NGEQTLSRDI YRLGHRFDFF RMLSCYYTTI GFYFSTMITV WTVYVFLYGR LYLVLSGLDE 1560 ALATGKRFVH NSPLQVALAS ESFVQLGFLM ALPMMMEIGL ERGFRTALSD FVLMQLQLAS 1620 VFFTFSLGTK THYYGRTLLH GGAEYRATGR GFVVFHAKFA ENYRLYSRSH FVKGIELMIL 1680 LVVYEIFGQS YRGAITYIFI TVSMWFMVGT WLFAPFLFNP SGFEWQKIVD DWTDWNKWIH 1740 NRGGIGVAPE KSWESWWDKE QGPLRHSGKR GTVVEILLAL RFFIYQYGLV YHLNITKQYN 1800 KSVLVYGISW VVIFSMLLVM KTVSVGRRRF SAEFQLVFRL MKGLIFISFI STIVILIALA 1860 HMTVLDIFVC ILAFMPTGWG LLLIAQAIKP VVEMVGLWGS VKALARGYEI LMGLLLFTPI 1920 AFLAWFPFVS EFQTRMLFNQ AFSRGLQISR ILGGHKKDRA TRNKE* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam04652 | DUF605 | 4.0e-9 | 62 | 176 | 125 | + Vta1 like. Vta1 (VPS20-associated protein 1) is a positive regulator of Vps4. Vps4 is an ATPase that is required in the multivesicular body (MVB) sorting pathway to dissociate the endosomal sorting complex required for transport (ESCRT). Vta1 promotes correct assembly of Vps4 and stimulates its ATPase activity through its conserved Vta1/SBP1/LIP5 region. | ||
| pfam14288 | FKS1_dom1 | 2.0e-54 | 342 | 458 | 118 | + 1,3-beta-glucan synthase subunit FKS1, domain-1. The FKS1_dom1 domain is likely to be the 'Class I' region just N-terminal to the first set of transmembrane helices that is involved in 1,3-beta-glucan synthesis itself. This family is found on proteins with family Glucan_synthase, pfam02364. | ||
| pfam02364 | Glucan_synthase | 0 | 1073 | 1814 | 817 | + 1,3-beta-glucan synthase component. This family consists of various 1,3-beta-glucan synthase components including Gls1, Gls2 and Gls3 from yeast. 1,3-beta-glucan synthase EC:2.4.1.34 also known as callose synthase catalyzes the formation of a beta-1,3-glucan polymer that is a major component of the fungal cell wall. The reaction catalyzed is:- UDP-glucose + {(1,3)-beta-D-glucosyl}(N) <=> UDP + {(1,3)-beta-D-glucosyl}(N+1). | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0000148 | 1,3-beta-D-glucan synthase complex |
| GO:0003843 | 1,3-beta-D-glucan synthase activity |
| GO:0006075 | (1->3)-beta-D-glucan biosynthetic process |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAD23015.1 | 0 | 33 | 1965 | 35 | 1969 | putative callose synthase 1 catalytic subunit [Oryza sativa Japonica Group] |
| DDBJ | BAD62105.1 | 0 | 1 | 1965 | 1 | 1959 | putative callose synthase 1 catalytic subunit [Oryza sativa Japonica Group] |
| GenBank | EEE66395.1 | 0 | 1 | 1965 | 1 | 1982 | hypothetical protein OsJ_22734 [Oryza sativa Japonica Group] |
| RefSeq | XP_002439067.1 | 0 | 1 | 1965 | 1 | 1965 | hypothetical protein SORBIDRAFT_10g030970 [Sorghum bicolor] |
| RefSeq | XP_002453103.1 | 0 | 21 | 1965 | 14 | 1942 | hypothetical protein SORBIDRAFT_04g038510 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2lxm_A | 0.01 | 66 | 175 | 21 | 128 | B Chain B, Lip5-chmp5 |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| callose biosynthesis | 13-BETA-GLUCAN-SYNTHASE-RXN | EC-2.4.1.34 | 1,3-β-glucan synthase |
