Basic Information | |
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Species | Brachypodium distachyon |
Cazyme ID | Bradi1g54950.1 |
Family | GT47 |
Protein Properties | Length: 549 Molecular Weight: 60634.3 Isoelectric Point: 8.8524 |
Chromosome | Chromosome/Scaffold: 1 Start: 53313677 End: 53320168 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 214 | 493 | 0 |
KLFKIYVYDEGEPPIYHDGPCHNIYSTEGRFIHAMEMENRMRTTDPGLAHVFFLPFSIAKMEKTIYVPGSHTMEPLRRTVFDYIDVLSTKHPYWNRSQGA DHFMLSCHDWGPYVSSVDGNLFSNSIRVLCNANTSEGFIPSKDVSLPEINHLNDFKKDIGGPSASGRPILAFFAGGNHGPVRPLLLKHWKGKDPDVQVSE YLPAGVSYVETMRRSKFCLCPSGFEVASPRVAEAIYVECVPVVIADDYVLPFSDVLSWPAFSLRVAVRDIPDIKRILSAV |
Full Sequence |
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Protein Sequence Length: 549 Download |
MRVSADGTAL PCLHGHGGKA ACALAVCVAF LTFLVVALDP RTRASSWLLS SSPPAVFSPT 60 LEKPSSRGSS NGGGPLLVTS SSGAAGKKKN SNGKEVLFRA FAVNATSWPG DVHGATPDYV 120 SVAAPAPSPA TQESGLGDAA NSDGVIQVIP QIHRERDAKL HRLELGLAKA RSTIMEASHN 180 KDNRPPLTDK DYVPVGPVYR NANAFHRSYL EMEKLFKIYV YDEGEPPIYH DGPCHNIYST 240 EGRFIHAMEM ENRMRTTDPG LAHVFFLPFS IAKMEKTIYV PGSHTMEPLR RTVFDYIDVL 300 STKHPYWNRS QGADHFMLSC HDWGPYVSSV DGNLFSNSIR VLCNANTSEG FIPSKDVSLP 360 EINHLNDFKK DIGGPSASGR PILAFFAGGN HGPVRPLLLK HWKGKDPDVQ VSEYLPAGVS 420 YVETMRRSKF CLCPSGFEVA SPRVAEAIYV ECVPVVIADD YVLPFSDVLS WPAFSLRVAV 480 RDIPDIKRIL SAVSPRRYIR MQRRVRAVRR HFMLNGVPQR YDVFHMILHS IWLRRLNVRI 540 HEDHVVGD* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 8.0e-61 | 212 | 493 | 301 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | EAZ03045.1 | 0 | 1 | 540 | 1 | 596 | hypothetical protein OsI_25187 [Oryza sativa Indica Group] |
RefSeq | NP_001059081.1 | 0 | 1 | 540 | 1 | 601 | Os07g0188700 [Oryza sativa (japonica cultivar-group)] |
RefSeq | XP_002459470.1 | 0 | 140 | 540 | 162 | 578 | hypothetical protein SORBIDRAFT_02g005180 [Sorghum bicolor] |
RefSeq | XP_002524591.1 | 0 | 128 | 542 | 89 | 504 | catalytic, putative [Ricinus communis] |
RefSeq | XP_002528630.1 | 0 | 189 | 545 | 213 | 570 | catalytic, putative [Ricinus communis] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |