Basic Information | |
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Species | Brachypodium distachyon |
Cazyme ID | Bradi1g63540.1 |
Family | GT57 |
Protein Properties | Length: 519 Molecular Weight: 58839.4 Isoelectric Point: 9.6195 |
Chromosome | Chromosome/Scaffold: 1 Start: 62686410 End: 62689156 |
Description | ALG6, ALG8 glycosyltransferase family |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT57 | 40 | 497 | 0 |
LLVRVLVSVGPYSGQGAAPKFGDYEAQRHWMELTLHLPTSDWYRNTSDNDLAYWGLDYPPLSAYQSLLHARLINASLPDTVALRSSRGFESPESKLLMRW TVLSSDLMVFFPAALWFVWAYMKDGVGGGGEKREGWMWLLAMVLINPCLVLIDHGHFQYNCISLGLTLGAIAGVLSRNELAAAALFSLAINHKQMSMYFA PAFFGHLLGKCLKRKYPILEVTKLGFVVFGTFALVWWPYLRSYQATMQVISRLAPFERGIYEDYVANFWCSTSVLIKWKRLFAIKPLKLMSLCATIFAFL PSFVQQVKSPSNLGFLYSLLNSSFSFYLFSYQVHEKSILLPLLPASLLALHEPHLYGWFTYYALFSMYPLICRDQLLLQYIAVLGLFFLIYYSPGASYVK GINVSSGTKAVLSLPLLCSILFHIVYLQIEPPKRYPFLFDALIMFICFSQFVILTLYT |
Full Sequence |
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Protein Sequence Length: 519 Download |
MAKPRKSRNP ASDLPAPARL PWQPPAQPVA TALLISLAAL LVRVLVSVGP YSGQGAAPKF 60 GDYEAQRHWM ELTLHLPTSD WYRNTSDNDL AYWGLDYPPL SAYQSLLHAR LINASLPDTV 120 ALRSSRGFES PESKLLMRWT VLSSDLMVFF PAALWFVWAY MKDGVGGGGE KREGWMWLLA 180 MVLINPCLVL IDHGHFQYNC ISLGLTLGAI AGVLSRNELA AAALFSLAIN HKQMSMYFAP 240 AFFGHLLGKC LKRKYPILEV TKLGFVVFGT FALVWWPYLR SYQATMQVIS RLAPFERGIY 300 EDYVANFWCS TSVLIKWKRL FAIKPLKLMS LCATIFAFLP SFVQQVKSPS NLGFLYSLLN 360 SSFSFYLFSY QVHEKSILLP LLPASLLALH EPHLYGWFTY YALFSMYPLI CRDQLLLQYI 420 AVLGLFFLIY YSPGASYVKG INVSSGTKAV LSLPLLCSIL FHIVYLQIEP PKRYPFLFDA 480 LIMFICFSQF VILTLYTNYK QWMLDLHPRP VGRRKKDL* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03155 | Alg6_Alg8 | 4.0e-100 | 49 | 499 | 466 | + ALG6, ALG8 glycosyltransferase family. N-linked (asparagine-linked) glycosylation of proteins is mediated by a highly conserved pathway in eukaryotes, in which a lipid (dolichol phosphate)-linked oligosaccharide is assembled at the endoplasmic reticulum membrane prior to the transfer of the oligosaccharide moiety to the target asparagine residues. This oligosaccharide is composed of Glc(3)Man(9)GlcNAc(2). The addition of the three glucose residues is the final series of steps in the synthesis of the oligosaccharide precursor. Alg6 transfers the first glucose residue, and Alg8 transfers the second one. In the human alg6 gene, a C->T transition, which causes Ala333 to be replaced with Val, has been identified as the cause of a congenital disorder of glycosylation, designated as type Ic OMIM:603147. |
Gene Ontology | |
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GO Term | Description |
GO:0005789 | endoplasmic reticulum membrane |
GO:0016758 | transferase activity, transferring hexosyl groups |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAC79743.1 | 0 | 1 | 518 | 1 | 517 | putative alpha 3 glucosyltransferase [Oryza sativa Japonica Group] |
RefSeq | NP_001058960.1 | 0 | 1 | 472 | 109 | 569 | Os07g0164500 [Oryza sativa (japonica cultivar-group)] |
RefSeq | NP_001145139.1 | 0 | 1 | 518 | 1 | 519 | hypothetical protein LOC100278369 [Zea mays] |
RefSeq | XP_002280181.1 | 0 | 30 | 516 | 31 | 514 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002305159.1 | 0 | 43 | 518 | 15 | 490 | predicted protein [Populus trichocarpa] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
dolichyl-diphosphooligosaccharide biosynthesis | RXN-5470 | EC-2.4.1.267 | Dol-P-Glc:Man9GlcNAc2-PP-Dol α-1,3-glucosyltransferase |