Basic Information | |
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Species | Brachypodium distachyon |
Cazyme ID | Bradi1g63740.1 |
Family | GT47 |
Protein Properties | Length: 458 Molecular Weight: 51659.1 Isoelectric Point: 8.6837 |
Chromosome | Chromosome/Scaffold: 1 Start: 62962556 End: 62965049 |
Description | exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 62 | 379 | 0 |
LRVFMYDLPLEFHFGLLDWKPGGAAAGGGLWPDVRHGVPEYPGGLNLQHSIEYWLTLDLLASEQGAPTPCNAVRVRDPARADVVFVPFFASLSFNRHSKV VPPARTSEDRALQRRLIEFLAARPEWRRSGGRDHVVLAHHPNGMLDARYKLWPCVFVLCDFGRYPHSVANIDKDVIAPYLHVVGNFFNDSAGYDARPTLL YFQGAIYRKDGGFIRQELYYLLKDEKDVHFSFGSVAGNGIEQSTQGMRASKFCLNIAGDTPSSNRLFDSIVSHCVPIIISDEIELPFEDVLDYSKFCIIV RGVDAVKKGFLINLIKGI |
Full Sequence |
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Protein Sequence Length: 458 Download |
MAASASCRSP LVWFFSLAAA LFFASWYLLL DSAAAPAALD ARRQGPRSAS PARKCDPATA 60 LLRVFMYDLP LEFHFGLLDW KPGGAAAGGG LWPDVRHGVP EYPGGLNLQH SIEYWLTLDL 120 LASEQGAPTP CNAVRVRDPA RADVVFVPFF ASLSFNRHSK VVPPARTSED RALQRRLIEF 180 LAARPEWRRS GGRDHVVLAH HPNGMLDARY KLWPCVFVLC DFGRYPHSVA NIDKDVIAPY 240 LHVVGNFFND SAGYDARPTL LYFQGAIYRK DGGFIRQELY YLLKDEKDVH FSFGSVAGNG 300 IEQSTQGMRA SKFCLNIAGD TPSSNRLFDS IVSHCVPIII SDEIELPFED VLDYSKFCII 360 VRGVDAVKKG FLINLIKGIS RQEWTSMWNK LKEVERHFEY QYPSQHDDAV QMIWKTIARK 420 VPSIRLKVNR LQRFSRFETN KTDESLPRSS WLENQAR* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 7.0e-44 | 62 | 361 | 310 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACF84601.1 | 0 | 54 | 456 | 60 | 461 | unknown [Zea mays] |
RefSeq | NP_001049980.1 | 0 | 39 | 455 | 47 | 466 | Os03g0324700 [Oryza sativa (japonica cultivar-group)] |
RefSeq | NP_001131151.1 | 0 | 66 | 456 | 1 | 390 | hypothetical protein LOC100192459 [Zea mays] |
RefSeq | NP_001136572.1 | 0 | 33 | 456 | 31 | 452 | hypothetical protein LOC100216694 [Zea mays] |
RefSeq | XP_002467934.1 | 0 | 49 | 456 | 55 | 461 | hypothetical protein SORBIDRAFT_01g036720 [Sorghum bicolor] |