Basic Information | |
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Species | Brachypodium distachyon |
Cazyme ID | Bradi1g73000.1 |
Family | GT47 |
Protein Properties | Length: 782 Molecular Weight: 88606.4 Isoelectric Point: 6.5739 |
Chromosome | Chromosome/Scaffold: 1 Start: 70587240 End: 70591425 |
Description | exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 336 | 690 | 0 |
KKRPLIYVYDLPAEFDSHLLEGRHFKLQCVNRIYDDKNRTIWTEQLYGAQMALYESILASPHRTLNGDEADYFYVPVLDSCLITRSDDAPHLLTPEDLHL RSYHALEYYRKAYDHISQRYAYWNRTSGRDHIWFFSWDEGACYAPKEIWNSMMLVHWGNTNTKHENSTTAYWADNWDDIPLDRRGNHPCFDPRKDLVLPA WKVPEPGAIWLKLWARPRINRTTLFYFNGNLGPAYEQGRPEDTYSMGIRQKLAAEFGSTPSKEGKLGRQHTANVTVTYLRSEKYYEELASSVFCGALPGD GWSGRMEDSMLQGCIPVIIQDGIFLPYENVLNYNSFAVRIQEHDIPNLIRILGGI |
Full Sequence |
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Protein Sequence Length: 782 Download |
MLTIRSAKCP WVFVGAAGAL VMLVATVHVF MVPILPSSLD FFGTRGRTTR PRNVFPGVGV 60 VDSRFRAQFP ADSYGAVMFR GAPWKPGVGR WLAGCHAGSS AVNITEVIGA KQCEKDCSGH 120 GVCNYDLGEC RCFHGYAGKG CEEVLKLECN FPSSPEWPVG RWVVSICPAQ CDTTRAMCFC 180 GPGTKYPERP VAEACGFKTT SPAKPDDPKI PDWKAPDPDV FTTNSSKPGW CNVDPQDAYS 240 SKVEFKLECD CKYDGLWGQF CETRVECSCI NQCSGHGQCR GGFCQCDSGY FGIDCSVPSA 300 YSLAYDWPSW LQSPANLPDL NKLSKSPINV NAVVKKKRPL IYVYDLPAEF DSHLLEGRHF 360 KLQCVNRIYD DKNRTIWTEQ LYGAQMALYE SILASPHRTL NGDEADYFYV PVLDSCLITR 420 SDDAPHLLTP EDLHLRSYHA LEYYRKAYDH ISQRYAYWNR TSGRDHIWFF SWDEGACYAP 480 KEIWNSMMLV HWGNTNTKHE NSTTAYWADN WDDIPLDRRG NHPCFDPRKD LVLPAWKVPE 540 PGAIWLKLWA RPRINRTTLF YFNGNLGPAY EQGRPEDTYS MGIRQKLAAE FGSTPSKEGK 600 LGRQHTANVT VTYLRSEKYY EELASSVFCG ALPGDGWSGR MEDSMLQGCI PVIIQDGIFL 660 PYENVLNYNS FAVRIQEHDI PNLIRILGGI NETQIEFMLG NVRQIWQRFF YRDSMLLEAQ 720 RQKRLYSEEA PWSVEVSKLE DSDDVFATFI QVLHYKLYND PWRQHLQEKE TGLPNICSKA 780 S* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd00054 | EGF_CA | 0.003 | 266 | 295 | 34 | + Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. | ||
pfam07974 | EGF_2 | 5.0e-5 | 267 | 295 | 31 | + EGF-like domain. This family contains EGF domains found in a variety of extracellular proteins. | ||
pfam03016 | Exostosin | 5.0e-67 | 335 | 690 | 359 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI29877.1 | 0 | 8 | 777 | 37 | 817 | unnamed protein product [Vitis vinifera] |
GenBank | EAZ25771.1 | 0 | 37 | 781 | 34 | 779 | hypothetical protein OsJ_09611 [Oryza sativa Japonica Group] |
GenBank | EEC74609.1 | 0 | 37 | 781 | 34 | 737 | hypothetical protein OsI_10218 [Oryza sativa Indica Group] |
RefSeq | NP_191322.3 | 0 | 1 | 777 | 1 | 788 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002277596.1 | 0 | 4 | 777 | 5 | 789 | PREDICTED: hypothetical protein [Vitis vinifera] |