Basic Information | |
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Species | Brachypodium distachyon |
Cazyme ID | Bradi1g78280.1 |
Family | GT47 |
Protein Properties | Length: 463 Molecular Weight: 51678.4 Isoelectric Point: 8.3719 |
Chromosome | Chromosome/Scaffold: 1 Start: 74324864 End: 74326252 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 39 | 387 | 0 |
CAGRRVHIRRLPPRFNTDLLGHCSTAFPLADHPSSTPSCASLANHGLGPRTHNRTRSWHRTDGRLLEPFFHRRVLDLPCLAADPAAADAVFLPYYASLDA LPFVLEPAMLNFSAIHGVPLAQFLERDRPDVLKRNHGHDHFLVLAGPAWDYAQPPESEPRLWGTTSILRRPEFVNFTFLTLESRAWPWQEHAIPHPTAFH PPTFPRLQAWIARARRSRRTSLMLYAGGVSRPSKPNIRGSILAECANRTDNVCSLIDCSGGACALDPAHYMIPMLRSRFCLQPPGDTPTRRSTFDAVLAG CVPVFFEHASARTQYGWHLPPERYDEFSVTIPKDSVVLGGVVIAETLAA |
Full Sequence |
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Protein Sequence Length: 463 Download |
MPRHLLITAC NFLPILFFFF FFFSSPVVVL TAAALPDPCA GRRVHIRRLP PRFNTDLLGH 60 CSTAFPLADH PSSTPSCASL ANHGLGPRTH NRTRSWHRTD GRLLEPFFHR RVLDLPCLAA 120 DPAAADAVFL PYYASLDALP FVLEPAMLNF SAIHGVPLAQ FLERDRPDVL KRNHGHDHFL 180 VLAGPAWDYA QPPESEPRLW GTTSILRRPE FVNFTFLTLE SRAWPWQEHA IPHPTAFHPP 240 TFPRLQAWIA RARRSRRTSL MLYAGGVSRP SKPNIRGSIL AECANRTDNV CSLIDCSGGA 300 CALDPAHYMI PMLRSRFCLQ PPGDTPTRRS TFDAVLAGCV PVFFEHASAR TQYGWHLPPE 360 RYDEFSVTIP KDSVVLGGVV IAETLAAVPE VEVARMRARL LEMAPRVVYR RHGTSTAGEM 420 GMDAIDIAVD GVLRRIRKRF KALQDGQAEA IYSMDDDNQE II* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-38 | 38 | 388 | 363 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAG13471.2 | 0 | 37 | 460 | 30 | 462 | AC026758_8 hypothetical protein [Oryza sativa Japonica Group] |
GenBank | ACF22751.1 | 0 | 1 | 462 | 1 | 462 | exostosin family protein [Brachypodium distachyon] |
GenBank | ACN36955.1 | 0 | 14 | 458 | 4 | 452 | unknown [Zea mays] |
RefSeq | NP_001065337.1 | 0 | 37 | 460 | 169 | 601 | Os10g0553600 [Oryza sativa (japonica cultivar-group)] |
RefSeq | XP_002466037.1 | 0 | 39 | 460 | 45 | 481 | hypothetical protein SORBIDRAFT_01g050380 [Sorghum bicolor] |