Basic Information | |
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Species | Brachypodium distachyon |
Cazyme ID | Bradi2g00690.1 |
Family | GT47 |
Protein Properties | Length: 399 Molecular Weight: 46398.8 Isoelectric Point: 9.5342 |
Chromosome | Chromosome/Scaffold: 2 Start: 408157 End: 409890 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 63 | 349 | 0 |
RLLKVFIYHDGAKPIFHSPELKGIYASEGWFMKLIEGNQNFVVRDPNRAHLFYLPYSSRQLEHNLYVPGSNTLEPLSIFVKNYIDMISAKFPYWNRTKGA DHFFVACHDWGPYTTKLHDELRRNTIKALCNADLSEGVFIRGRDVSLPETFVRSPRRPLRDIGGKPATERSILAFFAGQMHGRVRPILLQYWGGKDTDMR IYGRLPRRITRRMNYVQHMKSSKYCICPMGYEVNSPRIVEAIYYECIPVIIADNFVLPFDDALDWSTFSVVVPEKDVPRLKEILLRI |
Full Sequence |
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Protein Sequence Length: 399 Download |
MSGHAAPPPK REILLWSTAA DEELLYAKKE IVNAPLVTDD PDLYAPLFLN VSIFKRSYEL 60 MERLLKVFIY HDGAKPIFHS PELKGIYASE GWFMKLIEGN QNFVVRDPNR AHLFYLPYSS 120 RQLEHNLYVP GSNTLEPLSI FVKNYIDMIS AKFPYWNRTK GADHFFVACH DWGPYTTKLH 180 DELRRNTIKA LCNADLSEGV FIRGRDVSLP ETFVRSPRRP LRDIGGKPAT ERSILAFFAG 240 QMHGRVRPIL LQYWGGKDTD MRIYGRLPRR ITRRMNYVQH MKSSKYCICP MGYEVNSPRI 300 VEAIYYECIP VIIADNFVLP FDDALDWSTF SVVVPEKDVP RLKEILLRIP ESRYITMQSN 360 VKKVQKHFLW HAKPVKYDIF HMILHSVWFS RVNQAQIQ* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-70 | 61 | 349 | 305 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI23466.1 | 0 | 15 | 397 | 153 | 535 | unnamed protein product [Vitis vinifera] |
GenBank | EEC69788.1 | 0 | 1 | 398 | 137 | 536 | hypothetical protein OsI_00072 [Oryza sativa Indica Group] |
RefSeq | NP_001041784.1 | 0 | 1 | 398 | 151 | 550 | Os01g0107700 [Oryza sativa (japonica cultivar-group)] |
RefSeq | XP_002269459.1 | 0 | 15 | 397 | 153 | 535 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002457517.1 | 0 | 9 | 394 | 134 | 519 | hypothetical protein SORBIDRAFT_03g008610 [Sorghum bicolor] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
GT051299 | 334 | 52 | 384 | 0 |
BX834842 | 336 | 62 | 396 | 0 |
ES808098 | 347 | 30 | 376 | 0 |
HO277525 | 219 | 173 | 391 | 0 |
DT597828 | 261 | 21 | 281 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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