Basic Information | |
---|---|
Species | Brachypodium distachyon |
Cazyme ID | Bradi2g11140.1 |
Family | GH19 |
Protein Properties | Length: 294 Molecular Weight: 32075 Isoelectric Point: 6.7439 |
Chromosome | Chromosome/Scaffold: 2 Start: 9347364 End: 9348399 |
Description | Chitinase family protein |
View CDS |
External Links |
---|
NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GH19 | 50 | 286 | 0 |
SVETIVSEELYSSLFLHKDDAACPGKGFYTYASFIRATRKFPEFGATGDLCTRKREIAAFFAQISHETTGGWPAAPDGPYSWGLCYKEEIKPQSSYCDAT DKQWPCYPGKSYHGRGPIQLSWNFNYGPAGRALGFDGLRNPEQVSNCSDTAFQTALWFWMTPRQPKPSCHQVMVGEYCPSRADNVANRTAGFGLVTNIVN GALECNITDDARVNNRIGFYRRYSQVLGIDVGPNIDC |
Full Sequence |
---|
Protein Sequence Length: 294 Download |
MAFHEPASAN CDIRFVLSVA VFLAVAAASS VVSVDARYGG GAAAGQYCSS VETIVSEELY 60 SSLFLHKDDA ACPGKGFYTY ASFIRATRKF PEFGATGDLC TRKREIAAFF AQISHETTGG 120 WPAAPDGPYS WGLCYKEEIK PQSSYCDATD KQWPCYPGKS YHGRGPIQLS WNFNYGPAGR 180 ALGFDGLRNP EQVSNCSDTA FQTALWFWMT PRQPKPSCHQ VMVGEYCPSR ADNVANRTAG 240 FGLVTNIVNG ALECNITDDA RVNNRIGFYR RYSQVLGIDV GPNIDCAHQL PYN* 300 |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
COG3179 | COG3179 | 9.0e-7 | 100 | 210 | 132 | + Predicted chitinase [General function prediction only] | ||
cd00442 | lysozyme_like | 4.0e-9 | 107 | 217 | 111 | + lysozyme_like domain. This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases. All the members are involved in the hydrolysis of beta-1,4- linked polysaccharides. | ||
pfam00182 | Glyco_hydro_19 | 4.0e-120 | 54 | 286 | 233 | + Chitinase class I. | ||
cd00325 | chitinase_glyco_hydro_19 | 1.0e-125 | 55 | 286 | 232 | + Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases but they are smaller in size due to certain deletions. Despite any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the procaryotic/eucaryotic divergence. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0004568 | chitinase activity |
GO:0006032 | chitin catabolic process |
GO:0016998 | cell wall macromolecule catabolic process |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAC95376.1 | 0 | 18 | 290 | 4 | 277 | chitinase [Cynodon dactylon] |
GenBank | EAY73581.1 | 0 | 57 | 292 | 56 | 291 | hypothetical protein OsI_01465 [Oryza sativa Indica Group] |
RefSeq | NP_001042780.1 | 0 | 57 | 292 | 55 | 290 | Os01g0287600 [Oryza sativa (japonica cultivar-group)] |
RefSeq | XP_002457689.1 | 0 | 35 | 292 | 32 | 289 | hypothetical protein SORBIDRAFT_03g011710 [Sorghum bicolor] |
RefSeq | XP_002515175.1 | 0 | 51 | 293 | 33 | 275 | class I chitinase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 4dyg_B | 0 | 50 | 292 | 2 | 243 | A Chain A, Pectin Methylesterase Pema From Erwinia Chrysanthemi |
PDB | 4dyg_A | 0 | 50 | 292 | 2 | 243 | A Chain A, Pectin Methylesterase Pema From Erwinia Chrysanthemi |
PDB | 4dwx_B | 0 | 50 | 292 | 2 | 243 | A Chain A, Crystal Structure Of A Family Gh-19 Chitinase From Rye Seeds |
PDB | 4dwx_A | 0 | 50 | 292 | 2 | 243 | A Chain A, Crystal Structure Of A Family Gh-19 Chitinase From Rye Seeds |
PDB | 3cql_B | 0 | 51 | 292 | 2 | 242 | A Chain A, Crystal Structure Of Gh Family 19 Chitinase From Carica Papaya |
Metabolic Pathways | |||
---|---|---|---|
Pathway Name | Reaction | EC | Protein Name |
chitin degradation II | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
chitin degradation II | RXN-12623 | EC-3.2.1.14 | chitinase |
chitin degradation II | RXN-12624 | EC-3.2.1.14 | chitinase |
chitin degradation III (carnivorous plants) | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |