Basic Information | |
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Species | Brachypodium distachyon |
Cazyme ID | Bradi2g19710.1 |
Family | GT20 |
Protein Properties | Length: 903 Molecular Weight: 100846 Isoelectric Point: 5.2226 |
Chromosome | Chromosome/Scaffold: 2 Start: 17353885 End: 17358237 |
Description | trehalose-phosphatase/synthase 7 |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT20 | 72 | 569 | 0 |
AVGERLIVVANQLPVVARRRPDGRGWLFSWDDDSLLLRLRDGVPDEMEVLFVGTLRADVPASEQDEVSQTLIDGFRCAPVFLPADLYDRFYQNFCKGYLW PLFHYMLPFASAQSPKANAVSGGGRFDRASWESYVLANKYFFEKVVEVINPEDDYVWVHDYHLMALPTFLRRRFNRLRIGFFLHSPFPSSEIYRSLPVRE EILRTLLNCDLVGFHTFDYARHFLSCCSRMLGIEYESKRGYIGLDYFGRTVGIKIMPVGIHMGQLQSVLQLPDMQRKVAELRQQFEGKTVLLGVDDMDIF KGINLKLLAFENMLRMHPKWKGRAVLVQIANPARGKGKDIDSIRGEIQDSVERINKEFGRSGYSPIVFIDRNVPSVEKLAYYTVAECVVVTAVRDGMNLT PYEYIVCRQGIPGSESAPEVSGPSKSMLVVSEFIGCSPSLSGAIRVNPWNIEATAEALNEAISMSEREKQLRHEKHYRYVSTHDVAYWSRSFIQDLER |
Full Sequence |
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Protein Sequence Length: 903 Download |
MMSRSYTNLL DLAAGNFAAL GPAGGGRRRS GSFAAKRMPR VMTVPGTLSE LDDEDDELAA 60 TSSIASDVPS SAVGERLIVV ANQLPVVARR RPDGRGWLFS WDDDSLLLRL RDGVPDEMEV 120 LFVGTLRADV PASEQDEVSQ TLIDGFRCAP VFLPADLYDR FYQNFCKGYL WPLFHYMLPF 180 ASAQSPKANA VSGGGRFDRA SWESYVLANK YFFEKVVEVI NPEDDYVWVH DYHLMALPTF 240 LRRRFNRLRI GFFLHSPFPS SEIYRSLPVR EEILRTLLNC DLVGFHTFDY ARHFLSCCSR 300 MLGIEYESKR GYIGLDYFGR TVGIKIMPVG IHMGQLQSVL QLPDMQRKVA ELRQQFEGKT 360 VLLGVDDMDI FKGINLKLLA FENMLRMHPK WKGRAVLVQI ANPARGKGKD IDSIRGEIQD 420 SVERINKEFG RSGYSPIVFI DRNVPSVEKL AYYTVAECVV VTAVRDGMNL TPYEYIVCRQ 480 GIPGSESAPE VSGPSKSMLV VSEFIGCSPS LSGAIRVNPW NIEATAEALN EAISMSEREK 540 QLRHEKHYRY VSTHDVAYWS RSFIQDLERA CKDHFRKPCW GIGLGFGFRV VALDPNFAKL 600 NFDSIIMSYG RSKSRAIFLD YDGTLVPQAS INQKPSEELV NIINTLCSDR NNIVFIVSGR 660 SRDSLGSMFS SCPMLGIAAE HGYFLRWSRD EEWQTSTQSP DIGWMQMAEP VMNLYTEATD 720 GSYIETKETA LVWHHRDADQ GFGSSQAKEM LDHLESVLSN EAVSVKSGQF IVEVKPQGVS 780 KGLVAEKIIG SMKEKSQQAD FVLCIGDDRS DEDMFENIAD VMKRGIAAPK TPLFACTVGQ 840 KPSKAKFYLD DTYEVVSMLS ALADVSDPDP TAGLADDLAT SVSSLDISDE QIQFSNTTIE 900 GS* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PLN03063 | PLN03063 | 4.0e-172 | 76 | 867 | 824 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
PLN02205 | PLN02205 | 0 | 1 | 867 | 877 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
pfam00982 | Glyco_transf_20 | 0 | 75 | 569 | 498 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
PRK14501 | PRK14501 | 0 | 76 | 865 | 797 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
cd03788 | GT1_TPS | 0 | 76 | 568 | 493 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. |
Gene Ontology | |
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GO Term | Description |
GO:0003824 | catalytic activity |
GO:0005992 | trehalose biosynthetic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | EEC79533.1 | 0 | 1 | 902 | 1 | 899 | hypothetical protein OsI_20637 [Oryza sativa Indica Group] |
GenBank | EEE64369.1 | 0 | 1 | 902 | 1 | 899 | hypothetical protein OsJ_19211 [Oryza sativa Japonica Group] |
RefSeq | NP_001056050.1 | 0 | 1 | 902 | 1 | 899 | Os05g0517200 [Oryza sativa (japonica cultivar-group)] |
RefSeq | XP_002440081.1 | 0 | 1 | 902 | 1 | 906 | hypothetical protein SORBIDRAFT_09g025660 [Sorghum bicolor] |
RefSeq | XP_002458490.1 | 0 | 1 | 902 | 1 | 910 | hypothetical protein SORBIDRAFT_03g034640 [Sorghum bicolor] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 1gz5_D | 0 | 159 | 569 | 73 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 1gz5_C | 0 | 159 | 569 | 73 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 1gz5_B | 0 | 159 | 569 | 73 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 1gz5_A | 0 | 159 | 569 | 73 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 2wtx_D | 0 | 159 | 569 | 74 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
trehalose biosynthesis I | TREHALOSE6PSYN-RXN | EC-2.4.1.15 | α,α-trehalose-phosphate synthase (UDP-forming) |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
HO777775 | 761 | 116 | 867 | 0 |
HO779327 | 522 | 117 | 636 | 0 |
HO779327 | 243 | 632 | 870 | 0 |
HO795511 | 472 | 399 | 870 | 0 |
HO777775 | 93 | 1 | 93 | 0.62 |
Sequence Alignments (This image is cropped. Click for full image.) |
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