| Basic Information | |
|---|---|
| Species | Brachypodium distachyon |
| Cazyme ID | Bradi2g26000.1 |
| Family | GH19 |
| Protein Properties | Length: 398 Molecular Weight: 41355.2 Isoelectric Point: 5.3717 |
| Chromosome | Chromosome/Scaffold: 2 Start: 24238722 End: 24240279 |
| Description | basic chitinase |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH19 | 141 | 380 | 0 |
| VASILPRDLFERLLLHRNDNTCPARWFYTYDAFLAAAAAFPAFAGAEGNNNETRKREVAAFLGQTSHETTGGWDAAPDGPYSWGYCYKVEQQEPKPVYCE PSNEWPCTPGKKYYGRGPIQLSYNYNYGPAGQAPAIELDLLNNPDLVAADAVVAFKTALWFWMTPRDNKPSSHAVITGKWKPTAADIAAGRVPGYGVITN IINGGVECGIGPDLRVQDRIGFYRRYCDALGVDYGSNLDC | |||
| Full Sequence |
|---|
| Protein Sequence Length: 398 Download |
| MRAPSLATAV VLAILAAALA TAQARAENCG SQAGGATCAD NLCCSRFGFC GSSPEHCGDG 60 CQSQCSGGGP GPGPTCGSQA GGATCANCLC CSRFGFCGST PEHCGAGCQS QCSGCGPSPV 120 PTPAPGPGPA PGPTPPGNEG VASILPRDLF ERLLLHRNDN TCPARWFYTY DAFLAAAAAF 180 PAFAGAEGNN NETRKREVAA FLGQTSHETT GGWDAAPDGP YSWGYCYKVE QQEPKPVYCE 240 PSNEWPCTPG KKYYGRGPIQ LSYNYNYGPA GQAPAIELDL LNNPDLVAAD AVVAFKTALW 300 FWMTPRDNKP SSHAVITGKW KPTAADIAAG RVPGYGVITN IINGGVECGI GPDLRVQDRI 360 GFYRRYCDAL GVDYGSNLDC DNQRPFSSGF PAGFAAQ* 420 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| smart00270 | ChtBD1 | 6.0e-5 | 80 | 106 | 27 | + Chitin binding domain. | ||
| smart00270 | ChtBD1 | 2.0e-8 | 28 | 59 | 32 | + Chitin binding domain. | ||
| cd00442 | lysozyme_like | 3.0e-15 | 199 | 342 | 144 | + lysozyme_like domain. This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases. All the members are involved in the hydrolysis of beta-1,4- linked polysaccharides. | ||
| cd00325 | chitinase_glyco_hydro_19 | 1.0e-118 | 146 | 380 | 235 | + Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases but they are smaller in size due to certain deletions. Despite any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the procaryotic/eucaryotic divergence. | ||
| pfam00182 | Glyco_hydro_19 | 6.0e-123 | 144 | 380 | 237 | + Chitinase class I. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004568 | chitinase activity |
| GO:0006032 | chitin catabolic process |
| GO:0008061 | chitin binding |
| GO:0016998 | cell wall macromolecule catabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAF04453.1 | 0 | 76 | 388 | 23 | 322 | AF000964_1 chitinase [Poa pratensis] |
| GenBank | AAF04454.1 | 0 | 76 | 388 | 23 | 320 | AF000966_1 chitinase [Poa pratensis] |
| GenBank | AAR11388.1 | 0 | 76 | 387 | 23 | 319 | class I chitinase [Triticum aestivum] |
| GenBank | ACJ23248.1 | 0 | 76 | 387 | 24 | 316 | class I chitinase [Festuca arundinacea] |
| DDBJ | BAB82473.1 | 0 | 76 | 387 | 23 | 319 | chitinase 3 [Triticum aestivum] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3iwr_B | 0 | 76 | 397 | 4 | 309 | A Chain A, Crystal Structure Of Medicago Truncatula Ugt85h2- Insights Into The Structural Basis Of A Multifunctional (Iso) Flavonoid Glycosyltransferase |
| PDB | 3iwr_B | 0.0000000004 | 27 | 69 | 2 | 44 | A Chain A, Crystal Structure Of Medicago Truncatula Ugt85h2- Insights Into The Structural Basis Of A Multifunctional (Iso) Flavonoid Glycosyltransferase |
| PDB | 3iwr_A | 0 | 76 | 397 | 4 | 309 | A Chain A, Crystal Structure Of Medicago Truncatula Ugt85h2- Insights Into The Structural Basis Of A Multifunctional (Iso) Flavonoid Glycosyltransferase |
| PDB | 3iwr_A | 0.0000000004 | 27 | 69 | 2 | 44 | A Chain A, Crystal Structure Of Medicago Truncatula Ugt85h2- Insights Into The Structural Basis Of A Multifunctional (Iso) Flavonoid Glycosyltransferase |
| PDB | 2dkv_A | 0 | 76 | 397 | 4 | 309 | A Chain A, Crystal Structure Of Class I Chitinase From Oryza Sativa L. Japonica |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| chitin degradation II | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
| chitin degradation II | RXN-12623 | EC-3.2.1.14 | chitinase |
| chitin degradation II | RXN-12624 | EC-3.2.1.14 | chitinase |
| chitin degradation III (carnivorous plants) | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
