Basic Information | |
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Species | Brachypodium distachyon |
Cazyme ID | Bradi2g44880.1 |
Family | GT47 |
Protein Properties | Length: 474 Molecular Weight: 53617.3 Isoelectric Point: 10.1481 |
Chromosome | Chromosome/Scaffold: 2 Start: 45277781 End: 45280765 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 136 | 423 | 0 |
RILKVYIYQDGRRPIFHTPPLSGIYASEGWFMKLLKESRRFVVADGAKAHLFYLPYSSQHLRLSLYVPDSHNLRPLAVYLRDFVQGLAAKYPFWNRNRGA DHFLVACHDWGPYTTTAHRDLRRNSIKALCNADSSERIFSPGKDVSLPETTIRTPKRPLRYVGGLPVSRRRILAFFAGNVHGRVRPVLLKHWGDGRDDDM RVYGPLPNRVSRQMSYIQHMKNSRFCLCPMGHEVNSPRIVEALYYECVPVVIADNFVLPFSDVLDWTAFSVVVAEKDIPDLKKILQGI |
Full Sequence |
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Protein Sequence Length: 474 Download |
MVSASCCRVV GLGSLLAAAA ATTAFLTFSL PSSNGVSTAK LTVAVSVNAS STPPPPPPPP 60 PPTLATALPP PPPPPPPVAR PRKREPSYGR MTPEEALRYA KKEIMAAEPV VNDPDLYAPL 120 FRNVSQFKRS YELMERILKV YIYQDGRRPI FHTPPLSGIY ASEGWFMKLL KESRRFVVAD 180 GAKAHLFYLP YSSQHLRLSL YVPDSHNLRP LAVYLRDFVQ GLAAKYPFWN RNRGADHFLV 240 ACHDWGPYTT TAHRDLRRNS IKALCNADSS ERIFSPGKDV SLPETTIRTP KRPLRYVGGL 300 PVSRRRILAF FAGNVHGRVR PVLLKHWGDG RDDDMRVYGP LPNRVSRQMS YIQHMKNSRF 360 CLCPMGHEVN SPRIVEALYY ECVPVVIADN FVLPFSDVLD WTAFSVVVAE KDIPDLKKIL 420 QGISLRRYVA MHDCVKRLQR HFLWHARPLR YDLFHMILHS IWLSRVNHVE LLE* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 8.0e-74 | 138 | 423 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | EEC71161.1 | 0 | 85 | 473 | 111 | 499 | hypothetical protein OsI_03019 [Oryza sativa Indica Group] |
GenBank | EEE55063.1 | 0 | 1 | 473 | 29 | 482 | hypothetical protein OsJ_02778 [Oryza sativa Japonica Group] |
RefSeq | NP_001043679.1 | 0 | 85 | 473 | 111 | 501 | Os01g0640600 [Oryza sativa (japonica cultivar-group)] |
RefSeq | XP_002269459.1 | 0 | 93 | 471 | 158 | 535 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002456034.1 | 0 | 2 | 471 | 36 | 515 | hypothetical protein SORBIDRAFT_03g029210 [Sorghum bicolor] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |