Basic Information | |
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Species | Brachypodium distachyon |
Cazyme ID | Bradi2g49870.1 |
Family | GT20 |
Protein Properties | Length: 910 Molecular Weight: 101737 Isoelectric Point: 5.4298 |
Chromosome | Chromosome/Scaffold: 2 Start: 49863888 End: 49868755 |
Description | trehalose-phosphatase/synthase 7 |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT20 | 73 | 576 | 0 |
SGERLIVVSNQLPIVARRRPDGRGWSFSWDDDSLLLQLRDGIPDEMEVLFVGGVRADVPVTEQDEVSQALLDRFHCAAVFLPESLHDRFYHRFCKRHLWP LFHYMLPFSSASQTSSSSSSSSSASSPGSGRFDRGSWEAYVLANKFFFEKIVEVINPEDDYVWVHDYHLMALPTFLRRRFNRLRIGFFLHSPFPSSEIYR TLPVREEILKALLNCDLIGFHTFDYARHFLSCCSRMLGIEYQSKRGYIGLEYFGRTVGIKIMPVGVHMDQLQSVLCLPDRQWRVSELQQQFEGKTVLLGV DDMDIFKGINLKLLAFENMLRTHPKWQGRAVLVQIAKPVRGKGKDLEDIKAEICESCKRINGEFGQPGYSPVLLVDKDVSSVEKSAYYTIAECVVVTAVR DGMNLTPYEYIVSRQGIPRGESSSEVSGPKKSMLVVSEFIGCSPSLSGAIRVNPWNVEATAEAMNEAISMSEQEKQLRHEKHYRYVSTHDVAYWSKSFIQ DLER |
Full Sequence |
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Protein Sequence Length: 910 Download |
MMSRSYTNLL DLAEGNFAAL GPAGGGGRRR SFGMKRMSRV MTVPGTLSEL DGEDDSEPGA 60 TNSVASDVPS SVSGERLIVV SNQLPIVARR RPDGRGWSFS WDDDSLLLQL RDGIPDEMEV 120 LFVGGVRADV PVTEQDEVSQ ALLDRFHCAA VFLPESLHDR FYHRFCKRHL WPLFHYMLPF 180 SSASQTSSSS SSSSSASSPG SGRFDRGSWE AYVLANKFFF EKIVEVINPE DDYVWVHDYH 240 LMALPTFLRR RFNRLRIGFF LHSPFPSSEI YRTLPVREEI LKALLNCDLI GFHTFDYARH 300 FLSCCSRMLG IEYQSKRGYI GLEYFGRTVG IKIMPVGVHM DQLQSVLCLP DRQWRVSELQ 360 QQFEGKTVLL GVDDMDIFKG INLKLLAFEN MLRTHPKWQG RAVLVQIAKP VRGKGKDLED 420 IKAEICESCK RINGEFGQPG YSPVLLVDKD VSSVEKSAYY TIAECVVVTA VRDGMNLTPY 480 EYIVSRQGIP RGESSSEVSG PKKSMLVVSE FIGCSPSLSG AIRVNPWNVE ATAEAMNEAI 540 SMSEQEKQLR HEKHYRYVST HDVAYWSKSF IQDLERACKD HFRRTCWGIG LGFGFRVVAL 600 DPNFTKLNMD SIVMSYERSE SRTILLDYDG TLVPQTSINK TPSAEVLGII NTLCSDKRNT 660 VFLVSGRGRD KLGEWFSSCP KLGIAAEHGY FLRWSRDEEW QTCTQALDFG WMEMAEPVMN 720 LYTEATDGSY IETKESALVW HHQDADSGFG SSQAKEMLDH LESVLANEPV SVKSGQFIVE 780 VKPQGVSKGV IAEKILASMK ERGRQADFVL CIGDDRSDED MFENIADIIK RGMVAPKTPL 840 FACTVGQKPS KAKFYLDDTF EVATMLSALA DATDPEPVTG LAEELAVSVS SIDISGEQKQ 900 SSDRPFEGL* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PLN03063 | PLN03063 | 4.0e-165 | 76 | 874 | 839 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
PLN02205 | PLN02205 | 0 | 1 | 874 | 881 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
pfam00982 | Glyco_transf_20 | 0 | 75 | 576 | 506 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
PRK14501 | PRK14501 | 0 | 76 | 872 | 803 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
cd03788 | GT1_TPS | 0 | 76 | 575 | 500 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. |
Gene Ontology | |
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GO Term | Description |
GO:0003824 | catalytic activity |
GO:0005992 | trehalose biosynthetic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACN25869.1 | 0 | 37 | 908 | 1 | 873 | unknown [Zea mays] |
GenBank | ACN33296.1 | 0 | 1 | 908 | 1 | 911 | unknown [Zea mays] |
GenBank | EEC71477.1 | 0 | 1 | 901 | 1 | 908 | hypothetical protein OsI_03737 [Oryza sativa Indica Group] |
RefSeq | NP_001044248.1 | 0 | 1 | 901 | 1 | 907 | Os01g0749400 [Oryza sativa (japonica cultivar-group)] |
RefSeq | XP_002458490.1 | 0 | 1 | 908 | 1 | 909 | hypothetical protein SORBIDRAFT_03g034640 [Sorghum bicolor] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 2wtx_D | 0 | 149 | 576 | 64 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_C | 0 | 149 | 576 | 64 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_B | 0 | 149 | 576 | 64 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_A | 0 | 149 | 576 | 64 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 1uqu_B | 0 | 149 | 576 | 64 | 453 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
trehalose biosynthesis I | TREHALOSE6PSYN-RXN | EC-2.4.1.15 | α,α-trehalose-phosphate synthase (UDP-forming) |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
HO777775 | 783 | 97 | 870 | 0 |
HO779327 | 530 | 117 | 643 | 0 |
HO779327 | 239 | 639 | 877 | 0 |
HO795511 | 472 | 406 | 877 | 0 |
HO797286 | 472 | 408 | 874 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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