Basic Information | |
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Species | Brachypodium distachyon |
Cazyme ID | Bradi2g58060.1 |
Family | GT21 |
Protein Properties | Length: 518 Molecular Weight: 58355.8 Isoelectric Point: 8.6283 |
Chromosome | Chromosome/Scaffold: 2 Start: 56076829 End: 56081437 |
Description | Nucleotide-diphospho-sugar transferases superfamily protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT21 | 84 | 265 | 7.8e-33 |
PRVSVIMPLKGFGEHNLQNWRTQITSLYGGPVEFLFVVESKDDPAYRAVSCLIVDYKDKLEAKVVVAGFSTTCSQKIHNQLIGVEKMHKDSKYVLFLDDD VRLHPGTIGALTKEMVKNPEIFIQTGYPLDLPSGSLGSYCIYEYHMPCSIGFATGGRTFFLWGGCMMMHADDFRQDLYGLVT |
Full Sequence |
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Protein Sequence Length: 518 Download |
MAAMAAADAM LAAASRAVCS SVAVFFQIQG CCICLLLALG WTVASFVRKK EIRKMRRKMI 60 DGNSFAFLCD DVDELEHSVQ EKLPRVSVIM PLKGFGEHNL QNWRTQITSL YGGPVEFLFV 120 VESKDDPAYR AVSCLIVDYK DKLEAKVVVA GFSTTCSQKI HNQLIGVEKM HKDSKYVLFL 180 DDDVRLHPGT IGALTKEMVK NPEIFIQTGY PLDLPSGSLG SYCIYEYHMP CSIGFATGGR 240 TFFLWGGCMM MHADDFRQDL YGLVTGLRNG GYSDDMTLAA IAGQHKRLIT SPPVAVFPHP 300 LASDLSFSRY WNYLRKQTFV LESYVSKVNW MMNRALFATH CYLSWGFICP YAMALVHVAA 360 FVRAPYSAIV KEASDSSFGL KLVSFLFICT LTELVSMWNL TRVEIQLCNM LSPEGPKDSL 420 RSYNWGLVFI AVLVDNFLYP ISAFRSHFSQ SINWSGIRYY LRDGKISKIE RENRSKYTDL 480 GGKHLYSKRT YPPGKSLFGC SFLMSLVQWH QPKKYDV* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd04186 | GT_2_like_c | 4.0e-5 | 161 | 258 | 98 | + Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families. | ||
pfam13641 | Glyco_tranf_2_3 | 2.0e-5 | 84 | 250 | 174 | + Glycosyltransferase like family 2. Members of this family of prokaryotic proteins include putative glucosyltransferase, which are involved in bacterial capsule biosynthesis. | ||
cd02520 | Glucosylceramide_synthase | 2.0e-9 | 84 | 196 | 116 | + Glucosylceramide synthase catalyzes the first glycosylation step of glycosphingolipid synthesis. UDP-glucose:N-acylsphingosine D-glucosyltransferase (glucosylceramide synthase or ceramide glucosyltransferase) catalyzes the first glycosylation step of glycosphingolipid synthesis. Its product, glucosylceramide, serves as the core of more than 300 glycosphingolipids (GSL). GSLs are a group of membrane components that have the lipid portion embedded in the outer plasma membrane leaflet and the sugar chains extended to the outer environment. Several lines of evidence suggest the importance of GSLs in various cellular processes such as differentiation, adhesion, proliferation, and cell-cell recognition. In pathogenic fungus Cryptococcus neoformans, glucosylceramide serves as an antigen that elicits an antibody response in patients and it is essential for fungal growth in host extracellular environment. | ||
COG1215 | COG1215 | 1.0e-9 | 82 | 398 | 333 | + Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane] | ||
pfam13506 | Glyco_transf_21 | 1.0e-11 | 148 | 315 | 172 | + Glycosyl transferase family 21. This is a family of ceramide beta-glucosyltransferases - EC:2.4.1.80. |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACN34031.1 | 0 | 15 | 517 | 16 | 517 | unknown [Zea mays] |
DDBJ | BAD82732.1 | 0 | 15 | 517 | 13 | 515 | putative ceramide glucosyltransferase [Oryza sativa Japonica Group] |
GenBank | EEC71990.1 | 0 | 15 | 517 | 16 | 504 | hypothetical protein OsI_04841 [Oryza sativa Indica Group] |
GenBank | EEE55846.1 | 0 | 15 | 517 | 16 | 504 | hypothetical protein OsJ_04465 [Oryza sativa Japonica Group] |
RefSeq | XP_002458945.1 | 0 | 15 | 517 | 16 | 517 | hypothetical protein SORBIDRAFT_03g043150 [Sorghum bicolor] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
sphingolipid biosynthesis (plants) | RXN-7793 | EC-2.4.1.80 | ceramide glucosyltransferase |