| Basic Information | |
|---|---|
| Species | Brachypodium distachyon |
| Cazyme ID | Bradi2g59380.1 |
| Family | GT47 |
| Protein Properties | Length: 424 Molecular Weight: 47874.9 Isoelectric Point: 6.728 |
| Chromosome | Chromosome/Scaffold: 2 Start: 57094841 End: 57097739 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 56 | 351 | 0 |
| KLKVFVYEMPRKYNQYLLEKDNRCLYHMFAAEIFMHQFLLASAVRTMDPEEADWFYTPVYTTCDLTQQGFPLPFRAPRMMRSAVQYIAATWPYWNRTEGA DHFFLAPHDFGACFHYQEERAIERGILPVLRRATLVQTFGQRNHVCMQEGSITIPPYANPQKMQAHLISPGTPRSIFAYFRGLFYDMGNDPEGGYYARGA RASVWENFKDNPLFDMSTEHPSTYYEDMQRAIFCLCPLGWAPWSPRLVEAVVFGCIPVIIADDIVLPFADAIPWDQISVFVPEADVPRLDSILASV | |||
| Full Sequence |
|---|
| Protein Sequence Length: 424 Download |
| MGVTGRPSAA AVLLAGAVAC CAALAVAAQT QQQQQRKHVR ISGNAGDVLE DNPVGKLKVF 60 VYEMPRKYNQ YLLEKDNRCL YHMFAAEIFM HQFLLASAVR TMDPEEADWF YTPVYTTCDL 120 TQQGFPLPFR APRMMRSAVQ YIAATWPYWN RTEGADHFFL APHDFGACFH YQEERAIERG 180 ILPVLRRATL VQTFGQRNHV CMQEGSITIP PYANPQKMQA HLISPGTPRS IFAYFRGLFY 240 DMGNDPEGGY YARGARASVW ENFKDNPLFD MSTEHPSTYY EDMQRAIFCL CPLGWAPWSP 300 RLVEAVVFGC IPVIIADDIV LPFADAIPWD QISVFVPEAD VPRLDSILAS VPPEDVLRKQ 360 RLLASPAMKQ AVLFHQPAQP RDAFDQVLNG LARKLPHREG VFLRPGQKVI DWNAGQYDDL 420 KPW* |
| Functional Domains Download unfiltered results here | ||||||
|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
| pfam03016 | Exostosin | 4.0e-82 | 56 | 351 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACG43504.1 | 0 | 35 | 423 | 32 | 420 | secondary cell wall-related glycosyltransferase family 47 [Zea mays] |
| GenBank | ACR34554.1 | 0 | 6 | 423 | 2 | 412 | unknown [Zea mays] |
| GenBank | EAY77054.1 | 0 | 36 | 423 | 35 | 422 | hypothetical protein OsI_05011 [Oryza sativa Indica Group] |
| RefSeq | NP_001045262.1 | 0 | 36 | 423 | 35 | 422 | Os01g0926400 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002459015.1 | 0 | 7 | 423 | 3 | 415 | hypothetical protein SORBIDRAFT_03g044510 [Sorghum bicolor] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
