Basic Information | |
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Species | Brachypodium distachyon |
Cazyme ID | Bradi3g06390.1 |
Family | GT47 |
Protein Properties | Length: 406 Molecular Weight: 46099.9 Isoelectric Point: 9.0927 |
Chromosome | Chromosome/Scaffold: 3 Start: 4608735 End: 4611834 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 81 | 358 | 0 |
ERSFKVYIYPDGDPKTFYQTPRKLTGKYASEGYFFQNIRESRFRTEDPDSADLFFVPISPHKMRGKGTSYENMTIIVKDYVEGLINKYPYWNRTLGADHF FVTCHDVGVRAFEGLPFMVKNSIRVVCSPSYNVDFIPHKDVALPQVLQPFALPKGGNDVENRTNLGFWAGHRNSKIRVILARVWENDTELAISNNRISRA IGELVYQKQFYRTKFCICPGGSQVNSARISDSIHYGCVPVILSDYYDLPFNDVLDWKKFAIVLKERDVYELKSILKSI |
Full Sequence |
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Protein Sequence Length: 406 Download |
MAGRLGGAGS SSPLPRALLL LAAAALFSLS FLTLRSLRPA AVPSISLDES RLLAPPFSPA 60 PPRPSVYHSP EAFSAGYAEM ERSFKVYIYP DGDPKTFYQT PRKLTGKYAS EGYFFQNIRE 120 SRFRTEDPDS ADLFFVPISP HKMRGKGTSY ENMTIIVKDY VEGLINKYPY WNRTLGADHF 180 FVTCHDVGVR AFEGLPFMVK NSIRVVCSPS YNVDFIPHKD VALPQVLQPF ALPKGGNDVE 240 NRTNLGFWAG HRNSKIRVIL ARVWENDTEL AISNNRISRA IGELVYQKQF YRTKFCICPG 300 GSQVNSARIS DSIHYGCVPV ILSDYYDLPF NDVLDWKKFA IVLKERDVYE LKSILKSISQ 360 EEFVALHNSL VQIQKHFVWH SPPIPYDAFH MVMYELWLRH HVIKY* |
Functional Domains Download unfiltered results here | ||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
pfam03016 | Exostosin | 1.0e-60 | 80 | 358 | 297 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACG33948.1 | 0 | 1 | 405 | 1 | 403 | exostosin-like [Zea mays] |
GenBank | EAZ22017.1 | 0 | 27 | 405 | 29 | 408 | hypothetical protein OsJ_05674 [Oryza sativa Japonica Group] |
RefSeq | NP_001046127.1 | 0 | 27 | 405 | 29 | 402 | Os02g0187200 [Oryza sativa (japonica cultivar-group)] |
RefSeq | NP_001132213.1 | 0 | 1 | 405 | 1 | 403 | hypothetical protein LOC100193644 [Zea mays] |
RefSeq | XP_002453426.1 | 0 | 1 | 405 | 1 | 403 | hypothetical protein SORBIDRAFT_04g005890 [Sorghum bicolor] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
GT802014 | 261 | 83 | 343 | 0 |
GT034064 | 264 | 143 | 406 | 0 |
EX317869 | 278 | 105 | 382 | 0 |
EH770778 | 276 | 95 | 370 | 0 |
GO268625 | 269 | 80 | 348 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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