Basic Information | |
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Species | Brachypodium distachyon |
Cazyme ID | Bradi3g28605.1 |
Family | GT24 |
Protein Properties | Length: 1609 Molecular Weight: 181664 Isoelectric Point: 5.6986 |
Chromosome | Chromosome/Scaffold: 3 Start: 30000665 End: 30021194 |
Description | UDP-glucose:glycoprotein glucosyltransferases;transferases, transferring hexosyl groups;transferases, transferring glycosyl groups |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT24 | 1304 | 1551 | 0 |
INIFSVASGHLYERFLKIMILSVLKKTQRPVKFWFIKNYLSPQFKDVIPHMAQEYGFGYELITYKWPTWLHKQKEKQRIIWAYKILFLDVIFPLSLRKVI FVDADQIVRTDMGELYDMNLKGRPLAYTPFCDNNKEMDGYRFWKQGFWKDHLRGRPYHISALYVVDLAKFRQTAAGDTLRVVYETLSKDPNSLSNLDQDL PNYAQHTVPIFSLPQEWLWCESWCGNATKARAKTIDLCNNPMTKEPKL |
Full Sequence |
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Protein Sequence Length: 1609 Download |
MAAARGSRSG VSGAALALLA AVLVGCLAGG ASAAEIRRQK NVQVALRAKW AGTPLLLEAN 60 ELLSKEGKDL FWGFVDHWKE LDKGSECLTA KCCVQKIVED VHSLIGEPLA SIFEFSLTLR 120 SASPRLVLYR QLAEESLSSV PVEDDALEQI SGHGPVEGTC CWVDTGSALL FNSADLHKWL 180 EGSGKRTMDS TGQPELFDFD HVYPRSNVTA PVAILYGAVG TKCFKELHVR LAEASKKGKV 240 RYALRPVLPS GCQATSSFCA SIGAVDAVTL SGYGVELALK NMEYKAMDDT AIKKGVALED 300 PKTEDLGQEV RGFIFSKILE RKPELNDEAM AFRDYLLSST VSDTLEVWEL KDLGHQTAQR 360 ILHASDPLQS MQEINQNFPS VVSSLSRMKL DDSIKDEIIA NQRMVPPGKS LMALNGALIN 420 IEDLDLYLLM DMVREELSLA DQFIRLKLPK SAVHKILSAA PPAESNSFRV DFRASHVHYL 480 NNLEEDDLYK RWRSNLNELL MPVYPGQMRY IRKNLFHAVY VLDPASACGA ETIDTIMSLY 540 QDSVPVRFGI IMYSSRFINV IEENDGTHQV NDGSKSEDDT STLIIRLFLY IKETYSTQLA 600 FEFLSNIHKL RNGGDDYSEE PVEAHHVEEA FVDSVLSGAK SHPQDVLLKL QKENMYKQEA 660 EENSRFVHKL GLYKLHCCLL MNGLVHESNE DATMNAMNDE LPRIQEQVYY GHIQSHTDVL 720 EKFLSESSYK RYNPSITGKS TEKKRFVSLF ASYHQEDSVL HDINYLHSDG TTDDVKPVTH 780 LLAVDLSSKI GTKLLHEAIC YLMDGSNRAR VGLLLYARSD SASNILLMKD IIDRTISSFS 840 DKEKVLGFLH GFCKFYESQH MPASTAVGDR ISPMMDEVYN LAAETDLPVD DYKSWLASFS 900 ADTVLKRIDK LNDFLFGQLG LEFGSNAVIT NGRIFVVGVG DSFLTDDLGL LESMEYELRT 960 KYIHEIVEEV EWAGVDPDYL TSKFYSDITM LVSSSMSVRE RPSERAHFEI LHAEHSAIKL 1020 NYMNSSIHID AVIDPLSPAG QKLSPLLRIL WRQIQPSMRI VLNPISSLAD LPLKNYYRFV 1080 LPSMDDFSNT DYSVHGPKAF FSNMPLSKTL TMNIDVPEPW LVEPVVAIHD LDNILLENLG 1140 DVRTLQAVFE LEALLLTGHC MEKDREPPRG LQFILGTKQM PHLVDTLVMA NLGYWQMKVS 1200 PGVWYLQLAP GRSADLYELP SKLIAIDSLR GKLIHIEVQK KKGKEHEDLL NADDENHFQE 1260 KMDNKGWNSN LLKWASSFIS GDASLKKKSE KINDLKDARQ GETINIFSVA SGHLYERFLK 1320 IMILSVLKKT QRPVKFWFIK NYLSPQFKDV IPHMAQEYGF GYELITYKWP TWLHKQKEKQ 1380 RIIWAYKILF LDVIFPLSLR KVIFVDADQI VRTDMGELYD MNLKGRPLAY TPFCDNNKEM 1440 DGYRFWKQGF WKDHLRGRPY HISALYVVDL AKFRQTAAGD TLRVVYETLS KDPNSLSNLD 1500 QDLPNYAQHT VPIFSLPQEW LWCESWCGNA TKARAKTIDL CNNPMTKEPK LQGARRIVPE 1560 WVDFDSEARQ FTARILGENL ESAEATSVPS DAPKPDDKDS RQDVKDEL* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam01501 | Glyco_transf_8 | 0.0006 | 1308 | 1503 | 203 | + Glycosyl transferase family 8. This family includes enzymes that transfer sugar residues to donor molecules. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. This family includes Lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, and glycogenin glucosyltransferase. | ||
cd04194 | GT8_A4GalT_like | 3.0e-13 | 1304 | 1520 | 226 | + A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS. | ||
cd00505 | Glyco_transf_8 | 8.0e-57 | 1304 | 1551 | 257 | + Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis and glycogen synthesis. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. GT-8 comprises enzymes with a number of known activities: lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase, and N-acetylglucosaminyltransferase. GT-8 enzymes contains a conserved DXD motif which is essential in the coordination of a catalytic divalent cation, most commonly Mn2+. | ||
pfam06427 | UDP-g_GGTase | 1.0e-82 | 986 | 1191 | 212 | + UDP-glucose:Glycoprotein Glucosyltransferase. The N-terminal region of this group of proteins is required for correct folding of the ER UDP-Glc: glucosyltransferase. | ||
cd06432 | GT8_HUGT1_C_like | 4.0e-173 | 1304 | 1551 | 248 | + The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family. C-terminal domain of glycoprotein glucosyltransferase (UGT). UGT is a large glycoprotein whose C-terminus contains the catalytic activity. This catalytic C-terminal domain is highly homologous to Glycosyltransferase Family 8 (GT 8) and contains the DXD motif that coordinates donor sugar binding, characteristic for Family 8 glycosyltransferases. GT 8 proteins are retaining enzymes based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. The non-catalytic N-terminal portion of the human UTG1 (HUGT1) has been shown to monitor the protein folding status and activate its glucosyltransferase activity. |
Gene Ontology | |
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GO Term | Description |
GO:0003980 | UDP-glucose:glycoprotein glucosyltransferase activity |
GO:0006486 | protein glycosylation |
GO:0016757 | transferase activity, transferring glycosyl groups |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAD28382.1 | 0 | 1 | 1603 | 1 | 1624 | putative UDP-glucose:glycoprotein glucosyltransferase [Oryza sativa Japonica Group] |
GenBank | EEC73742.1 | 0 | 1 | 1312 | 1 | 1309 | hypothetical protein OsI_08377 [Oryza sativa Indica Group] |
GenBank | EEE57527.1 | 0 | 1 | 1603 | 1 | 1595 | hypothetical protein OsJ_07839 [Oryza sativa Japonica Group] |
RefSeq | XP_002268972.1 | 0 | 22 | 1604 | 13 | 1611 | PREDICTED: similar to EBS1 (EMS-MUTAGENIZED BRI1 SUPPRESSOR 1); UDP-glucose:glycoprotein glucosyltransferase/ transferase, transferring glycosyl groups / transferase, transferring hexosyl groups [Vitis vinifera] |
RefSeq | XP_002454743.1 | 0 | 1 | 1608 | 1 | 1568 | hypothetical protein SORBIDRAFT_04g036540 [Sorghum bicolor] |