| Basic Information | |
|---|---|
| Species | Brachypodium distachyon |
| Cazyme ID | Bradi3g35820.2 |
| Family | GT20 |
| Protein Properties | Length: 772 Molecular Weight: 88076.5 Isoelectric Point: 6.5065 |
| Chromosome | Chromosome/Scaffold: 3 Start: 38086622 End: 38092142 |
| Description | trehalose phosphate synthase |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT20 | 56 | 544 | 0 |
| FTERKIIVANFLPLNCMKDEAGQWSFSKDDDALLMQLKDGFSDETDVIYVGSLKVQIDPSDQDHVAQKLLREYRCIPTFLPSELQQQFYHGFCKQQLWPL FHYMLPICLDKGELFDRSLFRAYVRANKIFADKVMEAINTDDDCVWVHDYHLMLLPTFLRKRLHRIKLGFFLHSPFPSSEIYRTLPVRDEILKSLLNADL IGFQTFDYARHFLSCCSRLLGLHYESKRGYIGIEYFGRTVSLKILSVGVHVGRLESILKLPSTASKVQEIEQRYKGKMLMLGVDDMDIFKGISLKLLGLE LLLDRNPKLRGKVVLVQIVNPARSPGKDVEEAITEAVSVAERINVKYGSADYKPVVLIDNRIPFSEKIAFYAASDCCIVNAVRDGMNLVPYEYTVCRQGN DVMDKHRGFDKNHHHTSTLIVSEFVGCSPSLSGAFRVNPWSVDDVADALHSATDLTESEKRLRHDKHYRYVSTHDVAYWARSFIQDLER | |||
| Full Sequence |
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| Protein Sequence Length: 772 Download |
| MVSKSYSNLL EMSCGDSVDF RQPFKSLPRV VTSPGLISDP DWDSRSDDDS VGSASFTERK 60 IIVANFLPLN CMKDEAGQWS FSKDDDALLM QLKDGFSDET DVIYVGSLKV QIDPSDQDHV 120 AQKLLREYRC IPTFLPSELQ QQFYHGFCKQ QLWPLFHYML PICLDKGELF DRSLFRAYVR 180 ANKIFADKVM EAINTDDDCV WVHDYHLMLL PTFLRKRLHR IKLGFFLHSP FPSSEIYRTL 240 PVRDEILKSL LNADLIGFQT FDYARHFLSC CSRLLGLHYE SKRGYIGIEY FGRTVSLKIL 300 SVGVHVGRLE SILKLPSTAS KVQEIEQRYK GKMLMLGVDD MDIFKGISLK LLGLELLLDR 360 NPKLRGKVVL VQIVNPARSP GKDVEEAITE AVSVAERINV KYGSADYKPV VLIDNRIPFS 420 EKIAFYAASD CCIVNAVRDG MNLVPYEYTV CRQGNDVMDK HRGFDKNHHH TSTLIVSEFV 480 GCSPSLSGAF RVNPWSVDDV ADALHSATDL TESEKRLRHD KHYRYVSTHD VAYWARSFIQ 540 DLERACKDHY SQRCWAIGFG LNFRVIALSP GFRKLSLEHF LSSYNKATRR AIFLDYDGTI 600 VPQSSINKTP SAELISILNS LCNDPKNDVF IVSGRGRNSL DEWFAPCEKL GIAAEHGYFV 660 RWNQATEWES NYSSPDREWK HIAEPVMQVY TETTDGSFIE PKESALVWHY LDADHDFGSC 720 QAKELLDHLE RVLSNEPVGV KCGHFIVEVK PQVYAIWISY CLLYFIHEGS H* 780 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PLN03064 | PLN03064 | 5.0e-144 | 58 | 751 | 723 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PRK14501 | PRK14501 | 4.0e-177 | 59 | 752 | 707 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
| PLN02205 | PLN02205 | 0 | 1 | 752 | 759 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
| pfam00982 | Glyco_transf_20 | 0 | 58 | 544 | 491 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
| cd03788 | GT1_TPS | 0 | 61 | 543 | 483 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005992 | trehalose biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | EEC83577.1 | 0 | 1 | 752 | 1 | 752 | hypothetical protein OsI_29236 [Oryza sativa Indica Group] |
| GenBank | EEE68684.1 | 0 | 1 | 752 | 1 | 752 | hypothetical protein OsJ_27312 [Oryza sativa Japonica Group] |
| RefSeq | NP_001061805.1 | 0 | 1 | 752 | 1 | 752 | Os08g0414700 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002445486.1 | 0 | 1 | 752 | 1 | 752 | hypothetical protein SORBIDRAFT_07g020270 [Sorghum bicolor] |
| RefSeq | XP_002462305.1 | 0 | 1 | 752 | 1 | 752 | hypothetical protein SORBIDRAFT_02g023610 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1gz5_D | 0 | 142 | 544 | 74 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_C | 0 | 142 | 544 | 74 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_B | 0 | 142 | 544 | 74 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_A | 0 | 142 | 544 | 74 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 2wtx_D | 0 | 142 | 544 | 75 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| trehalose biosynthesis I | TREHALOSE6PSYN-RXN | EC-2.4.1.15 | α,α-trehalose-phosphate synthase (UDP-forming) |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| HO777775 | 678 | 79 | 752 | 0 |
| HO779327 | 515 | 97 | 611 | 0 |
| HO779327 | 146 | 607 | 752 | 0 |
| DV483505 | 287 | 166 | 452 | 0 |
| HO777775 | 75 | 1 | 73 | 0.25 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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