Basic Information | |
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Species | Brachypodium distachyon |
Cazyme ID | Bradi3g44420.1 |
Family | GT47 |
Protein Properties | Length: 429 Molecular Weight: 48253.5 Isoelectric Point: 6.6967 |
Chromosome | Chromosome/Scaffold: 3 Start: 46251837 End: 46254752 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 61 | 356 | 0 |
KLKVFVYDLPSKYNKMIVTKDPRCLSHMFAAEIFMHRFLFSSAVRTVNPEEADWFYTPVYTTCDLTRAGLPLPFKSPRMMRSAIQFISNKWPFWNRTDGG DHFFVVPHDFAACFHYQEENAIARGILPLLRHATLVQTFGQKNHVCLKDGSITIPPYAPPQKMQAHLIPPDTPRSIFVYFRGLFYDNGNDPEGGYYARGA RASLWENFKNNPLFDISTEHPATYYEDMQRSVFCLCPLGWAPWSPRLVEAVVFGCIPVIIADDIVLPFADAIPWDEIGVFVDEEDVPKLDSILTSI |
Full Sequence |
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Protein Sequence Length: 429 Download |
MAGARHGWLP MATLLVATCF YPLLLPPAAA AAEVDGRDAQ RNTERISGSA GDVLEDNPVG 60 KLKVFVYDLP SKYNKMIVTK DPRCLSHMFA AEIFMHRFLF SSAVRTVNPE EADWFYTPVY 120 TTCDLTRAGL PLPFKSPRMM RSAIQFISNK WPFWNRTDGG DHFFVVPHDF AACFHYQEEN 180 AIARGILPLL RHATLVQTFG QKNHVCLKDG SITIPPYAPP QKMQAHLIPP DTPRSIFVYF 240 RGLFYDNGND PEGGYYARGA RASLWENFKN NPLFDISTEH PATYYEDMQR SVFCLCPLGW 300 APWSPRLVEA VVFGCIPVII ADDIVLPFAD AIPWDEIGVF VDEEDVPKLD SILTSIPIDD 360 ILRKQRLLAN PSMKKAMLFP QPAQPRDAFH QILNGLARKL PHPESVYLQP GEKHVNWTAG 420 PVGDLKPW* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-84 | 61 | 356 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAD26319.1 | 0 | 40 | 428 | 45 | 433 | putative pectin-glucuronyltransferase [Oryza sativa Japonica Group] |
GenBank | EAZ23244.1 | 0 | 40 | 428 | 45 | 433 | hypothetical protein OsJ_06939 [Oryza sativa Japonica Group] |
RefSeq | NP_001149267.1 | 0 | 40 | 428 | 39 | 427 | secondary cell wall-related glycosyltransferase family 47 [Zea mays] |
RefSeq | XP_002446363.1 | 0 | 39 | 428 | 41 | 430 | hypothetical protein SORBIDRAFT_06g014730 [Sorghum bicolor] |
RefSeq | XP_002452172.1 | 0 | 1 | 428 | 1 | 432 | hypothetical protein SORBIDRAFT_04g021180 [Sorghum bicolor] |