| Basic Information | |
|---|---|
| Species | Brachypodium distachyon |
| Cazyme ID | Bradi3g48620.1 |
| Family | GT47 |
| Protein Properties | Length: 485 Molecular Weight: 53730.9 Isoelectric Point: 10.2498 |
| Chromosome | Chromosome/Scaffold: 3 Start: 50014941 End: 50016648 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 145 | 435 | 0 |
| EKRLKIWTYSEGEPPLAHLAPGTDIYSIEGQFLAEMEEPLNRFAARHPDEANVFLLPISVCNLVHYVYRLNTTAHLAPLRKLLADYVAVISDKHPYWNRS GGADHVLVSCHDWAPLVSEGSPELRDNAIRVLCNANVSEGFVPRKDATLPEVNLADGVLRLPTQGLPRQNRTTLAFFAGGMLGEIRRALLEQWAGREDPE MDVHEYLPPHGGGPGYDDYHALMGRARFCLCPSGFEVASPRVVESVFAGCVPVIISEGYPLPFGDVLDWSKMSVAVPAARIPELKAILRGV | |||
| Full Sequence |
|---|
| Protein Sequence Length: 485 Download |
| MEKKGGRRRG AGNAIAVPPL LAFVVVAPAV VFMLQSAVSG GGSATGSHTQ DRRRRLREQS 60 PLPQHVPGET QKASLQLPVK VVGGAIERGL ARSRAAIRRA ARAAPNGVES VRRIRSFKDA 120 SDAFVPRGAI YRNARASHRS YVEMEKRLKI WTYSEGEPPL AHLAPGTDIY SIEGQFLAEM 180 EEPLNRFAAR HPDEANVFLL PISVCNLVHY VYRLNTTAHL APLRKLLADY VAVISDKHPY 240 WNRSGGADHV LVSCHDWAPL VSEGSPELRD NAIRVLCNAN VSEGFVPRKD ATLPEVNLAD 300 GVLRLPTQGL PRQNRTTLAF FAGGMLGEIR RALLEQWAGR EDPEMDVHEY LPPHGGGPGY 360 DDYHALMGRA RFCLCPSGFE VASPRVVESV FAGCVPVIIS EGYPLPFGDV LDWSKMSVAV 420 PAARIPELKA ILRGVSERRY RVLRARVLQA QRHFVLHRPA RRFDMIHMVL HSIWLRRLNV 480 RLPY* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 3.0e-67 | 144 | 435 | 309 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAD19700.1 | 0 | 144 | 484 | 1 | 345 | exostosin-like protein [Oryza sativa Japonica Group] |
| GenBank | EAY86665.1 | 0 | 64 | 484 | 47 | 482 | hypothetical protein OsI_08049 [Oryza sativa Indica Group] |
| RefSeq | NP_197526.4 | 0 | 86 | 483 | 27 | 408 | catalytic [Arabidopsis thaliana] |
| Swiss-Prot | Q3E9A4 | 0 | 86 | 483 | 85 | 466 | GLYT5_ARATH RecName: Full=Probable glycosyltransferase At5g20260 |
| RefSeq | XP_002454169.1 | 0 | 144 | 484 | 1 | 338 | hypothetical protein SORBIDRAFT_04g025885 [Sorghum bicolor] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
