| Basic Information | |
|---|---|
| Species | Brachypodium distachyon |
| Cazyme ID | Bradi4g41580.1 |
| Family | GT20 |
| Protein Properties | Length: 878 Molecular Weight: 98583 Isoelectric Point: 6.1137 |
| Chromosome | Chromosome/Scaffold: 4 Start: 45626993 End: 45631165 |
| Description | trehalose-phosphatase/synthase 7 |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT20 | 72 | 562 | 0 |
| SSLASDRIIVVANTLPVRCERRPDGRGWSFSWDEDSLLLHLRDGLPEDMEVLYVGSLRADVPAAEQDDVAQALLDRFRCVPAFLPKDLSDRFYHGFCKQT LWPLFHYMLPFTSDHGGRFDRSNWEQYVLANKLFSQRVIEVLNPEDDYIWIHDYHLLALPSFLRRRFNRLRIGFFLHSPFPSSELYRSLPVRDEILKSLL NCDLIGFHTFDYARHFLSCCSRMLGIEYQSKRGYIGLDYFGRTVGIKIMPVGINMPQLKSQLQLPDLEWRVAELRKQFAGKTVLLGVDDMDIFKGINLKI LAFEQMLKIHPKWQGRAVLVQIANPRSGSGKDLEGLKAEIEESCARINGQFGRPGYSPVELVNRAISSVERMAYYTVAECVVVTAVRDGMNLTPYEYIVC RQGIPGLDGSSGDAPKRKSMLVVSEFIGCSPSLSGAIRVNPWNIDTTAEAMNESIALADNEKQLRHEKHYRYVSTHDVAYWSKSYVHDLER | |||
| Full Sequence |
|---|
| Protein Sequence Length: 878 Download |
| MFSRSYTNLL DLANGNLSAL DYGGGGGGGG GGGSGGGRPP RARRMQRTMT TPGTLAELDE 60 ERAGSVASDA QSSLASDRII VVANTLPVRC ERRPDGRGWS FSWDEDSLLL HLRDGLPEDM 120 EVLYVGSLRA DVPAAEQDDV AQALLDRFRC VPAFLPKDLS DRFYHGFCKQ TLWPLFHYML 180 PFTSDHGGRF DRSNWEQYVL ANKLFSQRVI EVLNPEDDYI WIHDYHLLAL PSFLRRRFNR 240 LRIGFFLHSP FPSSELYRSL PVRDEILKSL LNCDLIGFHT FDYARHFLSC CSRMLGIEYQ 300 SKRGYIGLDY FGRTVGIKIM PVGINMPQLK SQLQLPDLEW RVAELRKQFA GKTVLLGVDD 360 MDIFKGINLK ILAFEQMLKI HPKWQGRAVL VQIANPRSGS GKDLEGLKAE IEESCARING 420 QFGRPGYSPV ELVNRAISSV ERMAYYTVAE CVVVTAVRDG MNLTPYEYIV CRQGIPGLDG 480 SSGDAPKRKS MLVVSEFIGC SPSLSGAIRV NPWNIDTTAE AMNESIALAD NEKQLRHEKH 540 YRYVSTHDVA YWSKSYVHDL ERSCRDHFRR RCWGIGLGFG FRVVALDRNF KKLTVDSIVA 600 DYKKSNSRVI LLDYDGTLVP QTTINRTPNE TVVNIMNSLC ADKKNVVFIV SGRGRDSLAK 660 WFNSCPELGI AAEHGYFMRW TRDEQWKINN QCSEFGWMQM AEPVMNLYTE ATDGSYIETK 720 ESALVWHHQD ADPGFGSAQA KEMLDHLESV LANEPVSVKS GQHIVEVKPQ GVNKGFVAEK 780 ILSMLTENKR QADFVLCIGD DRSDEDMFEG IADIMKRSIV DPQTLLYACT VGQKPSKAKY 840 YLDDTNDVLN MLEALADASE EVGSPEESKI LSPSEEA* 900 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PLN03063 | PLN03063 | 5.0e-166 | 78 | 859 | 817 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PLN02205 | PLN02205 | 0 | 1 | 862 | 869 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
| pfam00982 | Glyco_transf_20 | 0 | 78 | 562 | 489 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
| PRK14501 | PRK14501 | 0 | 78 | 858 | 788 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
| cd03788 | GT1_TPS | 0 | 78 | 561 | 484 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005992 | trehalose biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | EAZ13427.1 | 0 | 1 | 872 | 1 | 872 | hypothetical protein OsJ_03344 [Oryza sativa Japonica Group] |
| GenBank | EEC71425.1 | 0 | 1 | 872 | 1 | 817 | hypothetical protein OsI_03616 [Oryza sativa Indica Group] |
| RefSeq | NP_001044141.1 | 0 | 1 | 872 | 1 | 872 | Os01g0730300 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002456290.1 | 0 | 1 | 877 | 1 | 891 | hypothetical protein SORBIDRAFT_03g033590 [Sorghum bicolor] |
| RefSeq | XP_002458490.1 | 0 | 1 | 859 | 1 | 874 | hypothetical protein SORBIDRAFT_03g034640 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1gz5_D | 0 | 161 | 562 | 73 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_C | 0 | 161 | 562 | 73 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_B | 0 | 161 | 562 | 73 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_A | 0 | 161 | 562 | 73 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 2wtx_D | 0 | 161 | 562 | 74 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| trehalose biosynthesis I | TREHALOSE6PSYN-RXN | EC-2.4.1.15 | α,α-trehalose-phosphate synthase (UDP-forming) |
| Hydropathy |
|---|
 |
| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| HO777775 | 779 | 99 | 871 | 0 |
| HO779327 | 513 | 119 | 628 | 0 |
| HO779327 | 236 | 625 | 860 | 0 |
| HO795511 | 469 | 392 | 860 | 0 |
| HO777775 | 96 | 1 | 95 | 0.014 |
| Sequence Alignments (This image is cropped. Click for full image.) |
|---|
 |
