| Basic Information | |
|---|---|
| Species | Brachypodium distachyon |
| Cazyme ID | Bradi5g20997.1 |
| Family | GT47 |
| Protein Properties | Length: 348 Molecular Weight: 40282.6 Isoelectric Point: 9.6916 |
| Chromosome | Chromosome/Scaffold: 5 Start: 23768773 End: 23771441 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 12 | 270 | 0 |
| VKIHQLLLKSRFRTLDKDEAHLFFVPSYVKCVRMTGALTDKEINQTYVKVLSQMPYFRRSGGRDHIFVFPSGAGAHLFRSWATFLNRSIILTPEGDRTDK RGISAFNTWKDIIIPGNVDDSMVKPDARAVQPIPLTKRKYLANFLGRAQGKAGRLKLVELAKQYPDKLESPELKLSGPDKLGRIDYFKHLRNAKFCLAPR GESSWTLRFYESFFVECVPVILSDEVELPFQNMIDYTEISIKWPSSKISPELFEYLESI | |||
| Full Sequence |
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| Protein Sequence Length: 348 Download |
| MRGPHHPPCT RVKIHQLLLK SRFRTLDKDE AHLFFVPSYV KCVRMTGALT DKEINQTYVK 60 VLSQMPYFRR SGGRDHIFVF PSGAGAHLFR SWATFLNRSI ILTPEGDRTD KRGISAFNTW 120 KDIIIPGNVD DSMVKPDARA VQPIPLTKRK YLANFLGRAQ GKAGRLKLVE LAKQYPDKLE 180 SPELKLSGPD KLGRIDYFKH LRNAKFCLAP RGESSWTLRF YESFFVECVP VILSDEVELP 240 FQNMIDYTEI SIKWPSSKIS PELFEYLESI PEERIEEMIA RGREVRCLWV YAPDLEPCSA 300 MAAILWELQR KVRRFHQSAQ TFWLHNRSTV NRDLVEFHQW TTTVPLP* 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-41 | 12 | 249 | 250 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | EAY93033.1 | 0 | 10 | 347 | 91 | 429 | hypothetical protein OsI_14833 [Oryza sativa Indica Group] |
| RefSeq | NP_001131485.1 | 0 | 10 | 347 | 89 | 426 | hypothetical protein LOC100192822 [Zea mays] |
| RefSeq | XP_002307477.1 | 0 | 10 | 347 | 123 | 460 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002458782.1 | 0 | 10 | 347 | 89 | 426 | hypothetical protein SORBIDRAFT_03g040220 [Sorghum bicolor] |
| RefSeq | XP_002526175.1 | 0 | 10 | 347 | 116 | 453 | catalytic, putative [Ricinus communis] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| CX668832 | 291 | 34 | 324 | 0 |
| FE707914 | 279 | 14 | 292 | 0 |
| JG790881 | 262 | 52 | 310 | 0 |
| EH692645 | 270 | 51 | 320 | 0 |
| FE707913 | 274 | 75 | 348 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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