Basic Information | |
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Species | Capsella rubella |
Cazyme ID | Carubv10000423m |
Family | GT47 |
Protein Properties | Length: 650 Molecular Weight: 73466 Isoelectric Point: 9.8573 |
Chromosome | Chromosome/Scaffold: 6 Start: 8981011 End: 8983601 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 318 | 601 | 0 |
KLLKVYAYKEGDKPIMHSPILRGIYASEGWFMKIIESNNKFVTKDPAKAHLFYLPFSSRMLEVTLYVQDSHSHRNLIKYLKDYIDFISVKYPFWNRTSGA DHFLAACHDWAPSETRKHMAKSIRALCNSDVKEGFVFGKDTSLPETFVRDPKKPLSNMGGKSATKRPILAFFAGKPDHGYLRPILLSYWGNNKDPDLKIF GKLPRTKGNKNYLQFMKTSKYCICAKGFEVNSPRVVEAIFYDCVPVIISDNFVPPFFEVLNWESFAIFVPEKDIPNLKKILMSI |
Full Sequence |
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Protein Sequence Length: 650 Download |
MRREFPWLWK VESRRLLWLL GLTFALVVTF QYIELPYAIS SIFSSTKIPI SRNSTSLIGN 60 STSAMAPSFS QSESDPVGDE EEVEVDQIFD STIATAPAVS PTTATLRPLF PSLKENATAP 120 AANADAPAAF SGLNTSQVKD NATAPAPAAS NQIPVKENAT APVANAEAPA ALPDLNPSPV 180 KKNATAPVAV LPVVNPSPVK ENRTMPTTSQ VPERSITKTY VGDAPPIVRF VPDVKENSKM 240 PDSGVMSISE MSKQLRQNRV SHYRLAKKPK WVTKPDMELL QAKYEIENAP IDDKDPLLYA 300 PLYRNVSMFK KSYELMEKLL KVYAYKEGDK PIMHSPILRG IYASEGWFMK IIESNNKFVT 360 KDPAKAHLFY LPFSSRMLEV TLYVQDSHSH RNLIKYLKDY IDFISVKYPF WNRTSGADHF 420 LAACHDWAPS ETRKHMAKSI RALCNSDVKE GFVFGKDTSL PETFVRDPKK PLSNMGGKSA 480 TKRPILAFFA GKPDHGYLRP ILLSYWGNNK DPDLKIFGKL PRTKGNKNYL QFMKTSKYCI 540 CAKGFEVNSP RVVEAIFYDC VPVIISDNFV PPFFEVLNWE SFAIFVPEKD IPNLKKILMS 600 IPERRYKSMQ MRVKKVQKHF LWHVKPEKYD MFHMILHSIW FNRVFQITV* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-65 | 316 | 601 | 305 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_195005.1 | 0 | 225 | 647 | 174 | 593 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | NP_197954.1 | 0 | 1 | 649 | 1 | 654 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002281263.1 | 0 | 1 | 649 | 1 | 668 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002309547.1 | 0 | 219 | 647 | 43 | 468 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002324801.1 | 0 | 265 | 647 | 13 | 395 | predicted protein [Populus trichocarpa] |