Basic Information | |
---|---|
Species | Capsella rubella |
Cazyme ID | Carubv10000494m |
Family | GT47 |
Protein Properties | Length: 614 Molecular Weight: 71047.1 Isoelectric Point: 10.0003 |
Chromosome | Chromosome/Scaffold: 6 Start: 6674074 End: 6676733 |
Description | Exostosin family protein |
View CDS |
External Links |
---|
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT47 | 281 | 564 | 0 |
ERTLKVYVYKEGNRPIFHTPILKGLYASEGWFMKLMEESKQYTVKDPRRAHLYYMPFSARMLEFTLYVRNSHNRTNLRQFLKEYTEHISSKYPFFNRTDG ADHFLVACHDWAPYETRHHMEHCIKALCNADVTAGFKIGRDISLPETYVRAAKNPQRDLGGKPPSQRRTLAFYAGSMHGYLRAILLQHWKDKDPEMKIFG RMPLGVASKMNYIEQMKSSKYCICPKGYEVNSPRVVESIFYECVPVIISDNFVPPFFEVLDWSAFSVIIAEKDIPRLKDILSSI |
Full Sequence |
---|
Protein Sequence Length: 614 Download |
MEIRSELRKH LRSGTRKWAI LVGIVALTHI LLLLSYGDVL RYLVPDGRRL KLPNESKKLM 60 TLSRNTLAVS VSEDSGIHVL EKNASISGFG LRNETEDDEG FDETADFESF EDAKDSVVVI 120 KQVVESSDTL YPLEMNVKQS AEMSTSKYGY QVQDVSVESQ KKVKTSMLSA SSSLAASSVG 180 KLPVSGNSSL LVSKQVSKKK KMRCNLPPKT VTTIEEMNRI LARHRRTSRA MRPRWSSRRD 240 EEILAARKEI ENAPVAKLER ELYPPIYRNV SMFKRSYELM ERTLKVYVYK EGNRPIFHTP 300 ILKGLYASEG WFMKLMEESK QYTVKDPRRA HLYYMPFSAR MLEFTLYVRN SHNRTNLRQF 360 LKEYTEHISS KYPFFNRTDG ADHFLVACHD WAPYETRHHM EHCIKALCNA DVTAGFKIGR 420 DISLPETYVR AAKNPQRDLG GKPPSQRRTL AFYAGSMHGY LRAILLQHWK DKDPEMKIFG 480 RMPLGVASKM NYIEQMKSSK YCICPKGYEV NSPRVVESIF YECVPVIISD NFVPPFFEVL 540 DWSAFSVIIA EKDIPRLKDI LSSIPEEKYV KMQMAVRKAQ RHFLWHAKPQ RYDLFHMVLH 600 SIWYNRVFQA KRR* |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 6.0e-68 | 280 | 564 | 305 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN76867.1 | 0 | 1 | 610 | 710 | 1391 | hypothetical protein [Vitis vinifera] |
EMBL | CAN76867.1 | 0 | 157 | 609 | 226 | 709 | hypothetical protein [Vitis vinifera] |
RefSeq | NP_197468.1 | 0 | 1 | 613 | 1 | 600 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002283936.1 | 0 | 206 | 613 | 1 | 410 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002514248.1 | 0 | 36 | 613 | 39 | 676 | catalytic, putative [Ricinus communis] |