Basic Information | |
---|---|
Species | Capsella rubella |
Cazyme ID | Carubv10000808m |
Family | GT47 |
Protein Properties | Length: 494 Molecular Weight: 56935.1 Isoelectric Point: 9.0315 |
Chromosome | Chromosome/Scaffold: 6 Start: 8802803 End: 8805222 |
Description | Exostosin family protein |
View CDS |
External Links |
---|
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT47 | 161 | 445 | 0 |
EKRFKVYVYEEGEPPLVHDGPCKSVYAVEGRFIYEMERRKARFRTYDPNQAYVYFLPFSVTWLVRYLYEGNSDAKPLRTFVSDYVRLVSTNHPFWNRTNG ADHFMLACHDWGPLTSRANKHLFNTSIRVLCNANSSEGFNPTKDVTLPEIKLVGGEVDPKLRLSATLSASPRPYLAFFAGGVHGPVRPILLKHWKQRDPD MPVFEYLPKHLNYYDFMRSSKFCFCPSGYEVASPRVIESIYSECIPVILSVNFVLPFTDVLRWETFSVLVDVSEIPRLKEILMSI |
Full Sequence |
---|
Protein Sequence Length: 494 Download |
MDKFQNRFTR FGFISVCIGS IALVLLLSRC STSFFDYALE KFEFSSPESE LRSNVYTITA 60 AEEEIENRAA AAVVVVDSRH VSQQILSLRS TNSSLQQSKP EKLNRINSVE RGLAKARASI 120 LEASSSSPSS HRNTTLFSID LPNPEIYRNP SALHRSYLEM EKRFKVYVYE EGEPPLVHDG 180 PCKSVYAVEG RFIYEMERRK ARFRTYDPNQ AYVYFLPFSV TWLVRYLYEG NSDAKPLRTF 240 VSDYVRLVST NHPFWNRTNG ADHFMLACHD WGPLTSRANK HLFNTSIRVL CNANSSEGFN 300 PTKDVTLPEI KLVGGEVDPK LRLSATLSAS PRPYLAFFAG GVHGPVRPIL LKHWKQRDPD 360 MPVFEYLPKH LNYYDFMRSS KFCFCPSGYE VASPRVIESI YSECIPVILS VNFVLPFTDV 420 LRWETFSVLV DVSEIPRLKE ILMSISDEKY EWLKRNLRSV RRHFELNDPP KRYDAFHLTL 480 HSIWLRRLNL KLT* |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-61 | 160 | 445 | 306 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI21064.1 | 0 | 99 | 492 | 84 | 477 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_197913.4 | 0 | 1 | 493 | 1 | 480 | catalytic [Arabidopsis thaliana] |
RefSeq | XP_002285237.1 | 0 | 160 | 492 | 1 | 333 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002324871.1 | 0 | 160 | 493 | 1 | 334 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002515489.1 | 0 | 16 | 492 | 17 | 480 | catalytic, putative [Ricinus communis] |