y
Basic Information | |
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Species | Capsella rubella |
Cazyme ID | Carubv10002876m |
Family | GT47 |
Protein Properties | Length: 514 Molecular Weight: 58325.1 Isoelectric Point: 9.7218 |
Chromosome | Chromosome/Scaffold: 6 Start: 5596903 End: 5600053 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 120 | 429 | 0 |
IKVYVYEMPKKFTLDLLWLFHNTYKETSNATSNGSPVHRLIEQHSIDYWLWADLISPESERRLKSVVRVHKQQDADFFYVPFFTTISFFLLEKQQCKALY REALKWVTDQPAWKRSEGRDHIFPIHHPWSFKSVRKFVKKAIWLLPDMDSTGNWYKPGQVSLEKDLILPYVPNVDICDAKCLSESAPMRTTFLFFRGRLK RNAGGKIRAKLGAELSGVKDVIISEGTAGEGGKLAAQGGMRSSLFCLCPAGDTPSSARLFDAIVSGCIPVIVSDELEFPFEGILNYKKAAVLVSSNDAIQ PGWLLNHLRS |
Full Sequence |
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Protein Sequence Length: 514 Download |
MFGKQQNHHH RATSPRTRSK TLILIISLFV VSLLVILFTF SSSTQPSVSY LNSSDRPETS 60 FVASLEHFLI HKAPKLTSPV RDDTVRGESE DDTRKLDEMV IERENRWLNE DPGYPVGIPI 120 KVYVYEMPKK FTLDLLWLFH NTYKETSNAT SNGSPVHRLI EQHSIDYWLW ADLISPESER 180 RLKSVVRVHK QQDADFFYVP FFTTISFFLL EKQQCKALYR EALKWVTDQP AWKRSEGRDH 240 IFPIHHPWSF KSVRKFVKKA IWLLPDMDST GNWYKPGQVS LEKDLILPYV PNVDICDAKC 300 LSESAPMRTT FLFFRGRLKR NAGGKIRAKL GAELSGVKDV IISEGTAGEG GKLAAQGGMR 360 SSLFCLCPAG DTPSSARLFD AIVSGCIPVI VSDELEFPFE GILNYKKAAV LVSSNDAIQP 420 GWLLNHLRSL KPFQIKDLQK NLAQYSRHFL YSSPAQPLGP EDLTWRMMAG KLVSIKLHTR 480 RSQRVVKGSR SVCRCDCWRP NSTASNSFSP LLS* 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-65 | 119 | 429 | 319 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI20132.1 | 0 | 127 | 504 | 1 | 378 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_197191.1 | 0 | 1 | 499 | 1 | 497 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002285599.1 | 0 | 57 | 504 | 62 | 512 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002325382.1 | 0 | 52 | 504 | 52 | 502 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002520033.1 | 0 | 52 | 504 | 51 | 503 | catalytic, putative [Ricinus communis] |