y
Basic Information | |
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Species | Capsella rubella |
Cazyme ID | Carubv10003248m |
Family | GT47 |
Protein Properties | Length: 574 Molecular Weight: 66414.5 Isoelectric Point: 10.1416 |
Chromosome | Chromosome/Scaffold: 6 Start: 3689009 End: 3691344 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 245 | 525 | 0 |
QTLKVYVHAEGDRPIFHQPEAMMEGIYASEGWFMKLMESSHRFLTKDPTEAHLFYLPFSSRMLQLKLYVHDSHSRRNLVKYLRNYIDLISSNHPFWNRTL GSDHFFTACHDWAPAETRGPYMNCIRSLCNADVGVDFVVGKDVSLPETKVSSAQNPNGKIGGNRPSKRTILAFFAGNLHGYVRPILLNHWSSRPEPDMKI FNRIDHKSYIRYMKRSRFCVCAKGYEVNSPRVVESILYGCVPVIISDNFVPPFLEILNWESFAVFVPEKEIPNLRKILVSI |
Full Sequence |
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Protein Sequence Length: 574 Download |
MGKLDKTNNC FQERSVVFNR NLSSFQVVMD QIRGLRFLGQ ARTCRVVLLM VLVVALVLGL 60 QYFELAPLSI VSHGNGNVSE FRESNGTTKS AENKTFLASQ QASSGFKPYN STTKVLKSIE 120 HKFLNDSPKT EASQRSRGNE TTSSVHSLQP KNPRIHKKHE ESQRNIKKPP LVVISITQMN 180 NMLWKRHNDP KNSLKPRWGS KVDEELKTAR DKIKNAALVK KDDTLYAPLY HNLSIFKRSY 240 ELMEQTLKVY VHAEGDRPIF HQPEAMMEGI YASEGWFMKL MESSHRFLTK DPTEAHLFYL 300 PFSSRMLQLK LYVHDSHSRR NLVKYLRNYI DLISSNHPFW NRTLGSDHFF TACHDWAPAE 360 TRGPYMNCIR SLCNADVGVD FVVGKDVSLP ETKVSSAQNP NGKIGGNRPS KRTILAFFAG 420 NLHGYVRPIL LNHWSSRPEP DMKIFNRIDH KSYIRYMKRS RFCVCAKGYE VNSPRVVESI 480 LYGCVPVIIS DNFVPPFLEI LNWESFAVFV PEKEIPNLRK ILVSIPVRRY VEMHKRVSKV 540 QKHFMWHDDE PVRYDIFHMI LHSVWYNRVF QTF* 600 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-60 | 247 | 525 | 301 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAC42362.1 | 0 | 29 | 573 | 1 | 546 | unknown protein [Arabidopsis thaliana] |
RefSeq | NP_196722.1 | 0 | 29 | 573 | 1 | 546 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | NP_974766.1 | 0 | 29 | 471 | 1 | 444 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002309547.1 | 0 | 161 | 571 | 56 | 467 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002516500.1 | 0 | 169 | 572 | 51 | 453 | catalytic, putative [Ricinus communis] |