Basic Information | |
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Species | Capsella rubella |
Cazyme ID | Carubv10003769m |
Family | GT47 |
Protein Properties | Length: 465 Molecular Weight: 53239.6 Isoelectric Point: 9.8036 |
Chromosome | Chromosome/Scaffold: 6 Start: 6863783 End: 6866469 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 131 | 415 | 0 |
EKRFKVWVYREGETPLVHMGPMNNIYGIEGQFVDEMERGMSPFAASHPEEAHAFLLPVSIANVVHYLYRPLVTYSREQLHKVFLDYVNVVAHKYPYWNRS LGADHFFVSCHDWAPDVSGSNPEQLKNLIRVLCNANTSEGFIPQRDVSIPEINIPRGYLGPPRLSNSSGHDRPILAFFAGGSHGYIRKILLQHWKDKDEE VQVHEYLAKRKDYFKLMAKARFCLCPSGYEVASPRVVAAINLGCVPVIISDHYSLPFSDVLDWTMFTIHVPSEKIPEIKTILKNV |
Full Sequence |
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Protein Sequence Length: 465 Download |
MKFSLAPTLV LLVLLLLYQH HSSPSNLNSN VLSSIFVDAT FIVAPSPSPS MSMEFSIAAS 60 SNFTLTSSPQ NKEKTKKNRI EEGLAKSRAA IREAVRLKKF ASDIKVEETF IPRGAVYRNA 120 YAFHQSHIEM EKRFKVWVYR EGETPLVHMG PMNNIYGIEG QFVDEMERGM SPFAASHPEE 180 AHAFLLPVSI ANVVHYLYRP LVTYSREQLH KVFLDYVNVV AHKYPYWNRS LGADHFFVSC 240 HDWAPDVSGS NPEQLKNLIR VLCNANTSEG FIPQRDVSIP EINIPRGYLG PPRLSNSSGH 300 DRPILAFFAG GSHGYIRKIL LQHWKDKDEE VQVHEYLAKR KDYFKLMAKA RFCLCPSGYE 360 VASPRVVAAI NLGCVPVIIS DHYSLPFSDV LDWTMFTIHV PSEKIPEIKT ILKNVSWRRY 420 RVLQRRVLQV QRHFVLNRPS QPFDMLRMLL HSVWLRRLNL RLPL* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-61 | 130 | 415 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI25537.1 | 0 | 72 | 463 | 83 | 476 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_197526.4 | 0 | 53 | 463 | 1 | 408 | catalytic [Arabidopsis thaliana] |
Swiss-Prot | Q3E9A4 | 0 | 17 | 463 | 26 | 466 | GLYT5_ARATH RecName: Full=Probable glycosyltransferase At5g20260 |
RefSeq | XP_002324625.1 | 0 | 130 | 463 | 1 | 334 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002531945.1 | 0 | 1 | 464 | 5 | 452 | catalytic, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 2jhp_A | 0.005 | 302 | 391 | 367 | 457 | A Chain A, Barley 1,3-1,4-Beta-Glucanase In Monoclinic Space Group |
PDB | 2jhc_A | 0.005 | 302 | 391 | 367 | 457 | A Chain A, Barley 1,3-1,4-Beta-Glucanase In Monoclinic Space Group |
PDB | 2jha_A | 0.005 | 302 | 391 | 367 | 457 | A Chain A, Barley 1,3-1,4-Beta-Glucanase In Monoclinic Space Group |
PDB | 2jh9_A | 0.005 | 302 | 391 | 367 | 457 | A Chain A, Barley 1,3-1,4-Beta-Glucanase In Monoclinic Space Group |
PDB | 2jh8_A | 0.005 | 302 | 391 | 367 | 457 | A Chain A, The Structure Of Bluetongue Virus Vp4 Reveals A Multifunctional Rna-capping Production-line |