Basic Information | |
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Species | Capsella rubella |
Cazyme ID | Carubv10004339m |
Family | GT47 |
Protein Properties | Length: 646 Molecular Weight: 74023.9 Isoelectric Point: 7.4487 |
Chromosome | Chromosome/Scaffold: 7 Start: 2907582 End: 2910794 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 316 | 599 | 0 |
EKKLKVYVYREGKRPVLHKPVLKGIYASEGWFMKQLKASKTFVTKNPRKAHLFYLPFSSKMLEETLYVPGSHSDKNLIEFLKNYLDMISSKYNFWNRTGG SDHFLVACHDWAPSETRQYMAKCIRALCNSDVSEGFVFGKDVALPETTILVPRRPLRALGGKPISQRQILAFFAGGMHGYLRPLLLQNWGGNRDPDMKIF SEIPKSKGKKSYMEYMKSTKYCICPKGHEVNSPRVVEALFYECVPVIISDNFVPPFFEVLNWESFAVFVLEKDIPDLKNILVSI |
Full Sequence |
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Protein Sequence Length: 646 Download |
LSFFLLNQFL PCDRLRAAAS VKSLLTGSCH NQYRFDLWLR DGDIGFLTSW SVHVEFCGNI 60 LYVCHLNLED AMKLLRFAGV VFVFITVFQF VNIRFYDGAI FSLPSEDKFL VSINESTEPP 120 IRPSGAELLY FSSSISAEGE ITGSKEDPIL GERTVPQEDH VVGSDKNDTN QSRQSLTDDA 180 KDKETLDLLP GTRSSSNESS ETIVEDADIA YENTRQVEIL ESKSDPSVDN LSSQVKSFMK 240 VSNSGVVSIT EMMNLLHQSH TSHVSLRLKR SSTVDQELLS ARIQIENPPL IENDPFLHAP 300 LYWNLSVFKR SYDLMEKKLK VYVYREGKRP VLHKPVLKGI YASEGWFMKQ LKASKTFVTK 360 NPRKAHLFYL PFSSKMLEET LYVPGSHSDK NLIEFLKNYL DMISSKYNFW NRTGGSDHFL 420 VACHDWAPSE TRQYMAKCIR ALCNSDVSEG FVFGKDVALP ETTILVPRRP LRALGGKPIS 480 QRQILAFFAG GMHGYLRPLL LQNWGGNRDP DMKIFSEIPK SKGKKSYMEY MKSTKYCICP 540 KGHEVNSPRV VEALFYECVP VIISDNFVPP FFEVLNWESF AVFVLEKDIP DLKNILVSIT 600 DERYREMQMR VKMVQKHFLW HSKPERFDIF HMILHSIWYN RVFQS* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-76 | 315 | 599 | 305 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_195005.1 | 0 | 35 | 644 | 2 | 592 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | NP_197954.1 | 0 | 70 | 644 | 12 | 651 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002281263.1 | 0 | 189 | 644 | 217 | 665 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002309547.1 | 0 | 224 | 644 | 47 | 467 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002324801.1 | 0 | 252 | 644 | 1 | 394 | predicted protein [Populus trichocarpa] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
ES808098 | 337 | 282 | 618 | 0 |
GT051299 | 334 | 306 | 634 | 0 |
GO247950 | 260 | 324 | 583 | 0 |
HE642074 | 289 | 311 | 599 | 0 |
GO247950 | 42 | 287 | 328 | 0.0004 |
Sequence Alignments (This image is cropped. Click for full image.) |
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