Basic Information | |
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Species | Capsella rubella |
Cazyme ID | Carubv10004511m |
Family | GT47 |
Protein Properties | Length: 554 Molecular Weight: 63797.7 Isoelectric Point: 10.1331 |
Chromosome | Chromosome/Scaffold: 7 Start: 14573701 End: 14576043 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 222 | 504 | 0 |
ERKLRVYVYKEGEKPIFHNAMTRGIYASEGWFMKLMESNKKFVVRDPRKAHLFYIPISIKSLRSSLGKEFQTPRSLADHLKEYVDLIAGKYKFWNRTGGA DHFLVACHDWGNKLTKKSMKNSVRALCNSNVAQGFRIGTDTALPVTYIRSAQSPLEYLGGKTPSERKILAFFAGSMHGYLRPILVQLWENKEPDMKIFGP MPRDPESKKKYREYMKSSRYCICARGYEVHTPRVVEAIINECVPVIIADNYVPPFFEVLNWEEFAVFVEEKDIPNLRNILLSI |
Full Sequence |
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Protein Sequence Length: 554 Download |
MRIRIVPRLE RFHHSDIRRL LSGTIFSVGF VVLLVQCFGI PSLNWSQVKV SVIDLSNSNV 60 TQVSVTNYIN LSYVDDGNGY DEDLGRENDV VISKEKVEIN VSVISTPNIS MRKTNMVVES 120 SVSSDPDSVL VRSKDIRKSD VLITRRHRSV AVVSISQMNS LLNQSFASFK SPKPRWSSAR 180 DSEMVSARFE IEKASFVHDN LGLSASVYRN ISKFQRSYDL MERKLRVYVY KEGEKPIFHN 240 AMTRGIYASE GWFMKLMESN KKFVVRDPRK AHLFYIPISI KSLRSSLGKE FQTPRSLADH 300 LKEYVDLIAG KYKFWNRTGG ADHFLVACHD WGNKLTKKSM KNSVRALCNS NVAQGFRIGT 360 DTALPVTYIR SAQSPLEYLG GKTPSERKIL AFFAGSMHGY LRPILVQLWE NKEPDMKIFG 420 PMPRDPESKK KYREYMKSSR YCICARGYEV HTPRVVEAII NECVPVIIAD NYVPPFFEVL 480 NWEEFAVFVE EKDIPNLRNI LLSIPEERYI GMQARVKAVQ QHFLWHKKPV KFDLFHMVLH 540 SIWYSRVHRI KTR* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-62 | 221 | 504 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAB08970.1 | 0 | 9 | 553 | 4 | 559 | unnamed protein product [Arabidopsis thaliana] |
EMBL | CAN76867.1 | 0 | 112 | 552 | 232 | 712 | hypothetical protein [Vitis vinifera] |
EMBL | CBI28021.1 | 0 | 112 | 553 | 232 | 665 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_198516.1 | 0 | 9 | 529 | 4 | 544 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002280595.1 | 0 | 112 | 553 | 230 | 663 | PREDICTED: hypothetical protein [Vitis vinifera] |