Basic Information | |
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Species | Capsella rubella |
Cazyme ID | Carubv10004820m |
Family | GT47 |
Protein Properties | Length: 443 Molecular Weight: 50848.3 Isoelectric Point: 7.104 |
Chromosome | Chromosome/Scaffold: 7 Start: 7041965 End: 7043656 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 39 | 388 | 0 |
CTGRWIHIRTLPSRFNLDLLSTCNRYPLTDDLCPYLANHGLGPKTHTRTRSWYRTDPLLLELIFHRRILEYPCLTPDPDLASAVYLPYYAGIDSLRYLYG PDLNSSADHGSDLLEFLTRDQPEIWSRRSGHDHFLVMARPAWDFSQPLTVDPPVWGTSFLERPEFFNLTALTLESRFWPWQEQAVPYPTSFHPHSLPFLE SWIRRVRRSRRTSLMLFAGGGGTSSSPNIRRSIRLECTSTNVTEPESKPDKICDFVDCSNGICEHDPIRFMRPMLQSSFCLQPPGDTPTRKATFDGIIAG CIPVFFEDQTAKMQYSWHLPESEYSEFSVTIPKEDVVFRGVRIQDVLMSI |
Full Sequence |
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Protein Sequence Length: 443 Download |
MASKSTVTTL TTFFFFIIIF ISIEPKVQSQ QISTVDSECT GRWIHIRTLP SRFNLDLLST 60 CNRYPLTDDL CPYLANHGLG PKTHTRTRSW YRTDPLLLEL IFHRRILEYP CLTPDPDLAS 120 AVYLPYYAGI DSLRYLYGPD LNSSADHGSD LLEFLTRDQP EIWSRRSGHD HFLVMARPAW 180 DFSQPLTVDP PVWGTSFLER PEFFNLTALT LESRFWPWQE QAVPYPTSFH PHSLPFLESW 240 IRRVRRSRRT SLMLFAGGGG TSSSPNIRRS IRLECTSTNV TEPESKPDKI CDFVDCSNGI 300 CEHDPIRFMR PMLQSSFCLQ PPGDTPTRKA TFDGIIAGCI PVFFEDQTAK MQYSWHLPES 360 EYSEFSVTIP KEDVVFRGVR IQDVLMSIPK EEVARMRERV IEMMPRVMYR RHGASMGLMN 420 KKDAVDLAID GVLEKIKSRS LI* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 7.0e-50 | 39 | 375 | 351 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_193989.1 | 0 | 1 | 439 | 1 | 434 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002267390.1 | 0 | 38 | 439 | 32 | 437 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002304426.1 | 0 | 21 | 439 | 12 | 428 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002329867.1 | 0 | 11 | 439 | 6 | 431 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002529790.1 | 0 | 13 | 439 | 8 | 448 | catalytic, putative [Ricinus communis] |