Basic Information | |
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Species | Capsella rubella |
Cazyme ID | Carubv10004872m |
Family | GT47 |
Protein Properties | Length: 427 Molecular Weight: 48748.6 Isoelectric Point: 8.585 |
Chromosome | Chromosome/Scaffold: 7 Start: 755026 End: 758669 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 102 | 379 | 0 |
EKRFKVYIYPDGDPNTFYQTPRKVTGKYASEGYFFQNIRESRFRTLDPDEADLFFIPISCHKMRGKGTSYENMTVIVQDYVDGLIAKYPYWNRTLGADHF FVTCHDVGVRAFEGSPLLIKNTIRVVCSPSYNVGFIPHKDVALPQVLQPFALPAGGNDVENRTTLGFWAGHRNSKIRVILARVWENDTELDISNNRINRA TGHLVYQKRFYRTKFCICPGGSQVNSARITDSIHYGCIPVILSDYYDLPFNDILGWRKFAVVLRERDVYNLKQILKNI |
Full Sequence |
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Protein Sequence Length: 427 Download |
MTIVKPSQFS GGGSSPLCSL KGSLLTVAVL TFVSLFYLSL NSLRTSPPSP VVVTPIHVPQ 60 TFAKEGNTDN NDEGAAPTTE EENYSDVYHS PEAFRLNYAE MEKRFKVYIY PDGDPNTFYQ 120 TPRKVTGKYA SEGYFFQNIR ESRFRTLDPD EADLFFIPIS CHKMRGKGTS YENMTVIVQD 180 YVDGLIAKYP YWNRTLGADH FFVTCHDVGV RAFEGSPLLI KNTIRVVCSP SYNVGFIPHK 240 DVALPQVLQP FALPAGGNDV ENRTTLGFWA GHRNSKIRVI LARVWENDTE LDISNNRINR 300 ATGHLVYQKR FYRTKFCICP GGSQVNSARI TDSIHYGCIP VILSDYYDLP FNDILGWRKF 360 AVVLRERDVY NLKQILKNIP QSEFVSLHNN LVKVQKHFQW NSPPVRFDAF HMIMYELWLR 420 HHVIKY* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 9.0e-61 | 101 | 379 | 298 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACU18220.1 | 0 | 13 | 426 | 4 | 409 | unknown [Glycine max] |
DDBJ | BAH56870.1 | 0 | 1 | 396 | 1 | 395 | AT4G38040 [Arabidopsis thaliana] |
RefSeq | NP_195517.1 | 0 | 1 | 426 | 1 | 425 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002266299.1 | 0 | 1 | 426 | 1 | 416 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002307304.1 | 0 | 17 | 426 | 1 | 406 | predicted protein [Populus trichocarpa] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
FY454337 | 315 | 21 | 335 | 0 |
EG459159 | 264 | 164 | 427 | 0 |
EH770778 | 275 | 117 | 391 | 0 |
JG847451 | 271 | 80 | 350 | 0 |
GO268625 | 269 | 101 | 369 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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