| Basic Information | |
|---|---|
| Species | Capsella rubella |
| Cazyme ID | Carubv10006479m |
| Family | GT47 |
| Protein Properties | Length: 536 Molecular Weight: 62199.5 Isoelectric Point: 9.7153 |
| Chromosome | Chromosome/Scaffold: 7 Start: 15656496 End: 15658103 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 150 | 471 | 0 |
| SCEGKGVYVYDLPSKFNRDLLVDCVDMVPWTNMCKYFKNEGFGEAIGNLGQGWFRTHQYALEPIFHSRVLKHPCRVYNESQAKIFYVPFYGGFDVLRWHF KNVSNVVKDRLGIEVLKWLESKESWKRNAGKDHVFVLGKISWDFRRSKLPWGSRFLELQGMNNPTKLLIERHPWEVNDIAVPHPTYFHPKTDYDIASWQV KMMNKPRRNVVSFAGGARPGNPHSIRSTLIEQCTTFSDQCRFLNCTNGSCNKPENVIELFQDSEFCLQPSGDSPTRKSVFDSLISGCIPVIFNPYTAYYQ YAWHLPENHRKYSVYISQEDVK | |||
| Full Sequence |
|---|
| Protein Sequence Length: 536 Download |
| MAILVSKRKP TTPSKRDDYN PRIFFFCKSI LMVAPFFVLY LWLSSTLIIS SRELKDPSVV 60 PSRYGKINSL KNDKSVRAIL SREDKKRFGV NIKHVLDHKA KNESEEEEQY QYIKPKSEGE 120 GYALRAVIKY IHEQRSWLPT ARKKGENPGS CEGKGVYVYD LPSKFNRDLL VDCVDMVPWT 180 NMCKYFKNEG FGEAIGNLGQ GWFRTHQYAL EPIFHSRVLK HPCRVYNESQ AKIFYVPFYG 240 GFDVLRWHFK NVSNVVKDRL GIEVLKWLES KESWKRNAGK DHVFVLGKIS WDFRRSKLPW 300 GSRFLELQGM NNPTKLLIER HPWEVNDIAV PHPTYFHPKT DYDIASWQVK MMNKPRRNVV 360 SFAGGARPGN PHSIRSTLIE QCTTFSDQCR FLNCTNGSCN KPENVIELFQ DSEFCLQPSG 420 DSPTRKSVFD SLISGCIPVI FNPYTAYYQY AWHLPENHRK YSVYISQEDV KGKRVNVVKK 480 LMAKTVREKE EMRSYIIHQL LPGLVYGDSN AKFEKFRDAF DITFDSLLEK INSLV* 540 |
| Functional Domains Download unfiltered results here | ||||||
|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
| pfam03016 | Exostosin | 2.0e-71 | 150 | 483 | 349 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_176534.2 | 0 | 78 | 535 | 194 | 664 | catalytic [Arabidopsis thaliana] |
| RefSeq | NP_198941.1 | 0 | 69 | 535 | 100 | 560 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002269913.1 | 0 | 95 | 534 | 114 | 537 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002299537.1 | 0 | 91 | 534 | 145 | 572 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002509789.1 | 0 | 123 | 534 | 159 | 566 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |
