Basic Information | |
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Species | Capsella rubella |
Cazyme ID | Carubv10007826m |
Family | GT47 |
Protein Properties | Length: 546 Molecular Weight: 62960.8 Isoelectric Point: 10.0477 |
Chromosome | Chromosome/Scaffold: 7 Start: 9374054 End: 9375936 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 203 | 488 | 0 |
LKVYIYPDGDKPIFHTPHLNGIYASEGWFMRLMESNTQFVTKNPERAHLFYMPYSVKQLQKTIFVPGSHNIKPLSIFLRDYVNMLSIKYPFWNRTHGSDH FLVACHDWGPYTVNEHPELRRNTIKALCNADLSDGVFVPGKDVSLPETSIRNAGRPLRNIGNGNRVSQRPILAFFAGNHHGRVRPQLLKHWRNKDNDMKI YGPLPHSVARKMTYVQHMKSSKYCLCPMGYEVNSPRIVEAIYYECVPVVIADNFMLPFSDVLDWSAFSVVVPEKEIPRLKEILLQI |
Full Sequence |
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Protein Sequence Length: 546 Download |
MVNMKSPLRV FIEVSIKELI KGFRRQRIRW RNAFLLGSIL TTIVVLLHTP TFSVFSDDDE 60 ETESSSSSSS SSPIYLNGSL HLNIQIVREA KVESFDDLTA TPTVQLNASE ESGTLLSTKS 120 RKRKRRRKIK DDLILPDPPP APRHVLSSSE RRALSLPPKK ALAYAKLEIQ RAPEIVNDTD 180 LFAPLFRNLS VFKRSYELME LILKVYIYPD GDKPIFHTPH LNGIYASEGW FMRLMESNTQ 240 FVTKNPERAH LFYMPYSVKQ LQKTIFVPGS HNIKPLSIFL RDYVNMLSIK YPFWNRTHGS 300 DHFLVACHDW GPYTVNEHPE LRRNTIKALC NADLSDGVFV PGKDVSLPET SIRNAGRPLR 360 NIGNGNRVSQ RPILAFFAGN HHGRVRPQLL KHWRNKDNDM KIYGPLPHSV ARKMTYVQHM 420 KSSKYCLCPM GYEVNSPRIV EAIYYECVPV VIADNFMLPF SDVLDWSAFS VVVPEKEIPR 480 LKEILLQIPM RRYLKMQSNV KMVQRHFLWS TKPRKYDVFH MILHSIWFNL LNQNQTSSTD 540 HDPDS* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-68 | 203 | 488 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAB10449.1 | 0 | 24 | 545 | 512 | 1024 | limonene cyclase like protein [Arabidopsis thaliana] |
EMBL | CBI23466.1 | 0 | 18 | 543 | 6 | 542 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_567512.2 | 0 | 1 | 545 | 1 | 542 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002269459.1 | 0 | 18 | 537 | 6 | 536 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002530666.1 | 0 | 72 | 535 | 54 | 524 | catalytic, putative [Ricinus communis] |