Basic Information | |
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Species | Capsella rubella |
Cazyme ID | Carubv10008022m |
Family | GT47 |
Protein Properties | Length: 469 Molecular Weight: 53931.9 Isoelectric Point: 9.2374 |
Chromosome | Chromosome/Scaffold: 16 Start: 92238 End: 96481 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 130 | 419 | 0 |
KRFKVWSYKEGEQPLVHDGPVNDIYGIEGQFIDELGNMIGGPSSRFRAVRPEEAHVFFLPFSVANIVHYVYKPIASPADFNRARLHRIFNDYVDVVARKY PFWNQSNGADHFMVSCHDWAPDVPDSKPEFFKDFMRGLCNANTSEGFKPSIDFSIPEINIPKGKLKPPFMGQNPENRTILAFFAGRAHGYIREVLFTHWK GKDKDVQVYDHLTKGQNYHELTGHSKFCLCPSGYEVASPREVEAIYSGCVPVVISDNYSLPFSDVLDWSKFSVEIPVDRIPDIKNILQEI |
Full Sequence |
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Protein Sequence Length: 469 Download |
MLNGSSKSLC LLGFPLILLL LIFLVFSFYL NYGSPPPKQF FSSVTMSSLL DHTNVLQSSP 60 SSSIYSPPIS IKRRSNLERR EEELRKARAA VRRAVRFKNY TSNEEVTYIP TGQIYRNSFA 120 FHQSHIEMMK RFKVWSYKEG EQPLVHDGPV NDIYGIEGQF IDELGNMIGG PSSRFRAVRP 180 EEAHVFFLPF SVANIVHYVY KPIASPADFN RARLHRIFND YVDVVARKYP FWNQSNGADH 240 FMVSCHDWAP DVPDSKPEFF KDFMRGLCNA NTSEGFKPSI DFSIPEINIP KGKLKPPFMG 300 QNPENRTILA FFAGRAHGYI REVLFTHWKG KDKDVQVYDH LTKGQNYHEL TGHSKFCLCP 360 SGYEVASPRE VEAIYSGCVP VVISDNYSLP FSDVLDWSKF SVEIPVDRIP DIKNILQEIP 420 HDKYIRMYQN VLKVRKHFVV NRPAQPFDVI HMILHSVWLR RLNIKLPS* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 7.0e-64 | 128 | 419 | 311 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABA18091.1 | 0 | 128 | 468 | 1 | 341 | exostosin family protein [Olimarabidopsis pumila] |
GenBank | ABA18105.1 | 0 | 46 | 468 | 1 | 423 | exostosin family protein [Capsella rubella] |
GenBank | ABA18110.1 | 0 | 129 | 468 | 1 | 340 | exostosin family protein [Arabidopsis arenosa] |
GenBank | ABG48476.1 | 0 | 46 | 468 | 1 | 425 | At3g42180 [Arabidopsis thaliana] |
RefSeq | NP_189804.4 | 0 | 36 | 468 | 36 | 470 | catalytic/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |