| Basic Information | |
|---|---|
| Species | Capsella rubella |
| Cazyme ID | Carubv10008703m |
| Family | AA3 |
| Protein Properties | Length: 574 Molecular Weight: 63464.3 Isoelectric Point: 7.0865 |
| Chromosome | Chromosome/Scaffold: 1 Start: 4936141 End: 4938998 |
| Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA3 | 85 | 563 | 0 |
| GKSFDYIVVGGGTAGCSLAATLSEKYSVLVIERGGSPFGDPFVEERKYFGYPLLNTDEYSSVAQSFTSLDGIENYRGRVLGGSSAINGGFYSRASDEFVK KAGWDKDLVQDSYKWVESKVVFMPELTQWQSVVQFGFLEAGFYPYNGYSLDHTLGTKIGGSIYDQCGKRHTSADLLGFGKPNCTTVLLNATVKSIIFDGN KTRAVGVRFMKSDGSSSKTYKAHVEKHRGEVILTAGALGSPQILLLSGIGPENHLKDLDIPVVVDLKQVGRKMSDNPAISLLVDRFSQNRTLEPPQVAAI AEGFKFILESEVLPTNITTTRISIAAKIAFPKSKGRLKLNSTDPRENPSVKFNYLENKEDLDACQEMVLHLQHVARSETVTFFLGTQAQDKLVAGDEELK SFCKQNVGTYYHYHGGCVVGSVVDEDYKVEGVKRLRVVDGSTFEESPGTNPMATVLMLGRYQGIKILKEREAKEEERFL | |||
| Full Sequence |
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| Protein Sequence Length: 574 Download |
| MYLFVDHLIG SLCLLHESSS LRLANSSTYK PSITLFFRQN FVSEYKQLRL DMSRLVFLFI 60 ISMLINLSQG VQMPYMTTDP KEVAGKSFDY IVVGGGTAGC SLAATLSEKY SVLVIERGGS 120 PFGDPFVEER KYFGYPLLNT DEYSSVAQSF TSLDGIENYR GRVLGGSSAI NGGFYSRASD 180 EFVKKAGWDK DLVQDSYKWV ESKVVFMPEL TQWQSVVQFG FLEAGFYPYN GYSLDHTLGT 240 KIGGSIYDQC GKRHTSADLL GFGKPNCTTV LLNATVKSII FDGNKTRAVG VRFMKSDGSS 300 SKTYKAHVEK HRGEVILTAG ALGSPQILLL SGIGPENHLK DLDIPVVVDL KQVGRKMSDN 360 PAISLLVDRF SQNRTLEPPQ VAAIAEGFKF ILESEVLPTN ITTTRISIAA KIAFPKSKGR 420 LKLNSTDPRE NPSVKFNYLE NKEDLDACQE MVLHLQHVAR SETVTFFLGT QAQDKLVAGD 480 EELKSFCKQN VGTYYHYHGG CVVGSVVDED YKVEGVKRLR VVDGSTFEES PGTNPMATVL 540 MLGRYQGIKI LKEREAKEEE RFLSPQGSPQ PQP* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PRK02106 | PRK02106 | 1.0e-40 | 86 | 359 | 330 | + choline dehydrogenase; Validated | ||
| TIGR03970 | Rv0697 | 9.0e-44 | 89 | 543 | 506 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
| TIGR01810 | betA | 4.0e-49 | 89 | 543 | 539 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
| COG2303 | BetA | 2.0e-55 | 81 | 544 | 542 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
| PLN02785 | PLN02785 | 2.0e-161 | 87 | 558 | 550 | + Protein HOTHEAD | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_172871.1 | 0 | 73 | 573 | 1 | 501 | glucose-methanol-choline (GMC) oxidoreductase family protein [Arabidopsis thaliana] |
| RefSeq | NP_563939.1 | 0 | 52 | 554 | 1 | 503 | glucose-methanol-choline (GMC) oxidoreductase family protein [Arabidopsis thaliana] |
| RefSeq | XP_002312249.1 | 0 | 76 | 561 | 1 | 494 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002315047.1 | 0 | 70 | 553 | 1 | 489 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002522448.1 | 0 | 63 | 555 | 19 | 526 | glucose-methanol-choline (gmc) oxidoreductase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3red_L | 0 | 87 | 556 | 26 | 520 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
| PDB | 3red_K | 0 | 87 | 556 | 26 | 520 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
| PDB | 3red_J | 0 | 87 | 556 | 26 | 520 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
| PDB | 3red_I | 0 | 87 | 556 | 26 | 520 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
| PDB | 3red_H | 0 | 87 | 556 | 26 | 520 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| EX098969 | 279 | 229 | 507 | 0 |
| HO796743 | 531 | 89 | 557 | 0 |
| JZ191231 | 269 | 81 | 339 | 0 |
| JZ194700 | 272 | 73 | 334 | 0 |
| JZ191665 | 243 | 73 | 310 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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