| Basic Information | |
|---|---|
| Species | Capsella rubella |
| Cazyme ID | Carubv10008714m |
| Family | AA3 |
| Protein Properties | Length: 570 Molecular Weight: 61891.2 Isoelectric Point: 8.3255 |
| Chromosome | Chromosome/Scaffold: 1 Start: 4373040 End: 4375599 |
| Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| AA3 | 41 | 563 | 0 |
| PTTSYYDYIIIGGGTAGCPLAATLSHNASVLLLERGGAPYNNPNITRLSSFGAALSDLSESSPSQRFVSEDGVINARARVLGGGSALNAGFYTRADTKYV RNMGWDGALANESYQWVEAKVAFQPPMGRWQTAVRDGLLEVGIVPNNGFTYDHINGTKFGGTIFDHNGHRHTAADLLEYADPKGITVLLHATVHRILFRT RGTTKPIANGVVYRDQTGQAHRAYLKEGALSEIILSAGTLGSPQLLMLSGVGPSAQLQAQNITVVMDQPQVGQGMYDNPMNAVFIPSPVPVEVSLIEVVG ITGEGTYVEAAGGENFGGGGSSGSSTRDYYAMFSPRATLLESNSMTKLSSAQPFQGGFLLEKVMGPLSTGHLELKTRNPRDNPVVTFNYFQHPDDLKRCV RGIQTIERVVQSKAFARYKYADMSFEYLLNLTASTPVNLRPPRSGPGASLPPSAEEFCQHTVTTIWHYHGGCVVGRVVDGDYKVIGIDRLRVIDMSTIGY CPGTNPQATVMMLGRYMGVKILR | |||
| Full Sequence |
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| Protein Sequence Length: 570 Download |
| MVDRFWSWGL FVALSLFIHS PICSSDKAPN YSFMRDARES PTTSYYDYII IGGGTAGCPL 60 AATLSHNASV LLLERGGAPY NNPNITRLSS FGAALSDLSE SSPSQRFVSE DGVINARARV 120 LGGGSALNAG FYTRADTKYV RNMGWDGALA NESYQWVEAK VAFQPPMGRW QTAVRDGLLE 180 VGIVPNNGFT YDHINGTKFG GTIFDHNGHR HTAADLLEYA DPKGITVLLH ATVHRILFRT 240 RGTTKPIANG VVYRDQTGQA HRAYLKEGAL SEIILSAGTL GSPQLLMLSG VGPSAQLQAQ 300 NITVVMDQPQ VGQGMYDNPM NAVFIPSPVP VEVSLIEVVG ITGEGTYVEA AGGENFGGGG 360 SSGSSTRDYY AMFSPRATLL ESNSMTKLSS AQPFQGGFLL EKVMGPLSTG HLELKTRNPR 420 DNPVVTFNYF QHPDDLKRCV RGIQTIERVV QSKAFARYKY ADMSFEYLLN LTASTPVNLR 480 PPRSGPGASL PPSAEEFCQH TVTTIWHYHG GCVVGRVVDG DYKVIGIDRL RVIDMSTIGY 540 CPGTNPQATV MMLGRYMGVK ILRERFTKK* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PRK02106 | PRK02106 | 5.0e-18 | 206 | 317 | 116 | + choline dehydrogenase; Validated | ||
| TIGR03970 | Rv0697 | 2.0e-27 | 47 | 554 | 544 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
| TIGR01810 | betA | 2.0e-28 | 47 | 554 | 564 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
| COG2303 | BetA | 2.0e-36 | 46 | 565 | 569 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
| PLN02785 | PLN02785 | 0 | 10 | 569 | 590 | + Protein HOTHEAD | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAF79648.1 | 0 | 34 | 569 | 1 | 539 | AC025416_22 F5O11.31 [Arabidopsis thaliana] |
| GenBank | AAF88098.1 | 0 | 28 | 569 | 5 | 549 | AC025417_26 T12C24.11 [Arabidopsis thaliana] |
| GenBank | AAL47442.1 | 0 | 1 | 569 | 1 | 572 | At1g12570/T12C24_9 [Arabidopsis thaliana] |
| RefSeq | NP_172718.2 | 0 | 1 | 569 | 1 | 572 | glucose-methanol-choline (GMC) oxidoreductase family protein [Arabidopsis thaliana] |
| RefSeq | XP_002298074.1 | 0 | 4 | 569 | 7 | 573 | predicted protein [Populus trichocarpa] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3gdp_B | 0 | 32 | 565 | 13 | 517 | A Chain A, Crystal Structure Of Galactose Oxidase, W290h Mutant |
| PDB | 3gdp_A | 0 | 32 | 565 | 13 | 517 | A Chain A, Crystal Structure Of Galactose Oxidase, W290h Mutant |
| PDB | 3gdn_B | 0 | 32 | 565 | 13 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
| PDB | 3gdn_A | 0 | 32 | 565 | 13 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
| PDB | 1ju2_B | 0 | 32 | 565 | 13 | 517 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
