Basic Information | |
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Species | Capsella rubella |
Cazyme ID | Carubv10009012m |
Family | GT47 |
Protein Properties | Length: 480 Molecular Weight: 54376.4 Isoelectric Point: 8.548 |
Chromosome | Chromosome/Scaffold: 1 Start: 12081183 End: 12083321 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 55 | 403 | 0 |
NGINVFVAELPRSLNYGLLENYWSSSSPDSRIPTDPDHPTRKTHLPKPDTYPPYPENPLIKQYSAEYWIMGDLETSPEKRIGSFAKRVFTESDADVVFVP FFATLSAEMELGNGKGSFRKKSGNEDYQRQRQVLDFVKNTKAWKRSNGRDHVFVLTDPVAMWHVREEIALSILLVVDFGGWFRQDSKSSNGTSLPERIEH TQVSVIKDVIVPYTHLLPRLDLSQNLRRHSLLYFKGAKHRHRGGLIREKLWDLLVEEPGVVMEEGFPNATGREQSIRGMRNSEFCLHPAGDTPTSCRLFD AIQSLCIPVIVSDTIELPFEGIIDYSEFSVFVSVSDALTPKWLANHLRK |
Full Sequence |
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Protein Sequence Length: 480 Download |
MVPKITSMAS TRPLCSIPYL LLSLSLLFVV SLLFFFSNSL ISDPNQKISH ITLQNGINVF 60 VAELPRSLNY GLLENYWSSS SPDSRIPTDP DHPTRKTHLP KPDTYPPYPE NPLIKQYSAE 120 YWIMGDLETS PEKRIGSFAK RVFTESDADV VFVPFFATLS AEMELGNGKG SFRKKSGNED 180 YQRQRQVLDF VKNTKAWKRS NGRDHVFVLT DPVAMWHVRE EIALSILLVV DFGGWFRQDS 240 KSSNGTSLPE RIEHTQVSVI KDVIVPYTHL LPRLDLSQNL RRHSLLYFKG AKHRHRGGLI 300 REKLWDLLVE EPGVVMEEGF PNATGREQSI RGMRNSEFCL HPAGDTPTSC RLFDAIQSLC 360 IPVIVSDTIE LPFEGIIDYS EFSVFVSVSD ALTPKWLANH LRKFSEREKE TFRSRMAKVQ 420 TVFVYDNGQA NGIGPIEPDG AVNHIWKKVQ EKVPMVKEAV IRERRKPAGA SVPLRCQCI* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-59 | 91 | 404 | 326 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_564443.1 | 0 | 1 | 479 | 1 | 477 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002270238.1 | 0 | 1 | 478 | 1 | 439 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002325567.1 | 0 | 15 | 478 | 13 | 475 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002327326.1 | 0 | 33 | 478 | 5 | 448 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002533317.1 | 0 | 41 | 478 | 39 | 477 | catalytic, putative [Ricinus communis] |