| Basic Information | |
|---|---|
| Species | Capsella rubella |
| Cazyme ID | Carubv10009077m |
| Family | GT47 |
| Protein Properties | Length: 462 Molecular Weight: 52617.4 Isoelectric Point: 9.6507 |
| Chromosome | Chromosome/Scaffold: 1 Start: 7502877 End: 7505473 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT47 | 86 | 384 | 0 |
| LSLKIYVYDENEIDGLKELLYGRDESVKTTACLKGQWGSQVKIHKLLLESKFRTIKKHEADLFFVPAYVKCVRMLGGLNDKEINQTYVKVLSQMPYFRRS GGRDHIFVFPSGAGAHLFRSWSTFINRSIILTPEADRTDKKDTTAFNTWKDIIIPGNVDDAMTKNGQPDVRPLPVSKRKYLANYLGRAQGKAGRLKLIEL SKQYPDKLECPDLKFSGTEKFGRTTYFEHLRNAKFCLAPRGESSWTLRFYESFFVECVPVLLSDHAELPFQNVIDYAQVSIKWPSTRIGTELLDYLASI | |||
| Full Sequence |
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| Protein Sequence Length: 462 Download |
| MASLTSKPRN FGAYSHYATP CTRTHQIGAL FLVVSTFFVT RLFDQWFSES NSVTPAIDLR 60 LTSSNAGITT ENGILRWPER GYGSHLSLKI YVYDENEIDG LKELLYGRDE SVKTTACLKG 120 QWGSQVKIHK LLLESKFRTI KKHEADLFFV PAYVKCVRML GGLNDKEINQ TYVKVLSQMP 180 YFRRSGGRDH IFVFPSGAGA HLFRSWSTFI NRSIILTPEA DRTDKKDTTA FNTWKDIIIP 240 GNVDDAMTKN GQPDVRPLPV SKRKYLANYL GRAQGKAGRL KLIELSKQYP DKLECPDLKF 300 SGTEKFGRTT YFEHLRNAKF CLAPRGESSW TLRFYESFFV ECVPVLLSDH AELPFQNVID 360 YAQVSIKWPS TRIGTELLDY LASISDKDIE GMISRGRKIR CLLVYGPDSA SCSAVKGILW 420 ELQRKVRHFH QSTETFWMHN GSFVNRELVQ FSGWKPPMPL P* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-43 | 88 | 384 | 309 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAF87908.1 | 0 | 1 | 461 | 1 | 414 | AC015447_18 Hypothetical protein [Arabidopsis thaliana] |
| GenBank | AAL75891.1 | 0 | 1 | 461 | 1 | 462 | At1g21480/F24J8_23 [Arabidopsis thaliana] |
| GenBank | AAM61682.1 | 0 | 1 | 461 | 1 | 462 | unknown [Arabidopsis thaliana] |
| RefSeq | NP_564141.1 | 0 | 1 | 461 | 1 | 462 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | NP_973879.1 | 0 | 1 | 385 | 1 | 386 | exostosin family protein [Arabidopsis thaliana] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| BX841155 | 335 | 1 | 334 | 0 |
| CX668832 | 291 | 148 | 438 | 0 |
| EX093096 | 277 | 1 | 276 | 0 |
| CD825121 | 244 | 156 | 399 | 0 |
| FE707914 | 279 | 128 | 406 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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