Basic Information | |
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Species | Capsella rubella |
Cazyme ID | Carubv10011126m |
Family | CBM57 |
Protein Properties | Length: 1013 Molecular Weight: 112271 Isoelectric Point: 7.8373 |
Chromosome | Chromosome/Scaffold: 1 Start: 10208767 End: 10215003 |
Description | receptor-like kinase in flowers 1 |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
CBM57 | 409 | 594 | 1.7e-26 |
LHVNCGGSDIYVKEKKTKELYEGDGGVEGGAAKYYLKPDANWGFSSTGDFMDDNNFQNTRFTMFVPASNLSDLYKTARIAPVSLTYFHACLENGNYTINL DFAEMRFTNDENYSRLGRRLFDIYIQEKLVAKDFNIMDEAKGAQKSLTKTFTANVTNHFLTIRLRWAGKGTTRIPTRGVYGPLISA |
Full Sequence |
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Protein Sequence Length: 1013 Download |
MKKKKDVPNI FAFSVFAIII CFRFYGINAI KLPQEEVDAL QQIANTLGSR FWKFDAEGCK 60 IEKVGLTETP PPTAKQEIEC ECSPTNETDC HIVKIAFKDH NLPGTLPQIV KLPYLREIDL 120 AYNYLNGTLP REWAYSNLTF ISLLVNRLSG EIPKEFGNSS ALTYLDLESN DFSGTIPQEL 180 GNLVHLKTLL LSSNKLTGNL PASLARLQNM TDFRINDLQL TGTIPSYIQN WKELKRLEMI 240 ASGLTGPIPS VISGLSNLAN LRISDIGGPV QPFPLLKNVT ELSKLILKNC NISGHIPAYL 300 SSFKGLETLD LSFNKLVGKI PSFAHAENLR FIILAGNKLE GEAPDELLRD GITLDLSYNN 360 LKWQSPESRS CRPNMNLNLN LFQSTSTKKS SKFLPCINDF KCPRYSSCLH VNCGGSDIYV 420 KEKKTKELYE GDGGVEGGAA KYYLKPDANW GFSSTGDFMD DNNFQNTRFT MFVPASNLSD 480 LYKTARIAPV SLTYFHACLE NGNYTINLDF AEMRFTNDEN YSRLGRRLFD IYIQEKLVAK 540 DFNIMDEAKG AQKSLTKTFT ANVTNHFLTI RLRWAGKGTT RIPTRGVYGP LISAISISSD 600 SKPCSRPDTG MSRGAYIAVG VGAPCLLILI VGILWWCGCL PLCGKRRKDP YEDELPSGTF 660 TLRQIKFATD DFNPTNKIGE GGFGAVFKGV LADGRVVAVK QLSSKSRQGN REFLNEIGAI 720 SCLQHPNLVK LHGFCVERAQ LLLVYEYMEN NSLSSALFSP KHKQIPLDWS TRFQICCGIA 780 KGLAFLHEES PLKFVHRDIK ATNILLDKDL TPKISDFGLA RLDEEEKTHI STKVAGTIGY 840 MAPEYALWGY LTFKADVYSF GVLVLEIVAG VTNSNFMAAG DSVCLLEWAN ECLESGHLMQ 900 VVDERLRPEV DKKEAETIIK VALVCSSASP TDRPIMSEVV AMLEGLYPVP ESTPGISKNS 960 GDIRFKAFKD LKKGMENSSK TQRSVKSYPS SSSISSGAGQ VVQETNKEES RN* 1020 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd00180 | PKc | 2.0e-51 | 678 | 867 | 194 | + Catalytic domain of Protein Kinases. Protein Kinases (PKs), catalytic (c) domain. PKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine or tyrosine residues on protein substrates. The PK family is part of a larger superfamily that includes the catalytic domains of RIO kinases, aminoglycoside phosphotransferase, choline kinase, phosphoinositide 3-kinase (PI3K), and actin-fragmin kinase. PKs make up a large family of serine/threonine kinases, protein tyrosine kinases (PTKs), and dual-specificity PKs that phosphorylate both serine/threonine and tyrosine residues of target proteins. Majority of protein phosphorylation, about 95%, occurs on serine residues while only 1% occurs on tyrosine residues. Protein phosphorylation is a mechanism by which a wide variety of cellular proteins, such as enzymes and membrane channels, are reversibly regulated in response to certain stimuli. PKs often function as components of signal transduction pathways in which one kinase activates a second kinase, which in turn, may act on other kinases; this sequential action transmits a signal from the cell surface to target proteins, which results in cellular responses. The PK family is one of the largest known protein families with more than 100 homologous yeast enzymes and 550 human proteins. A fraction of PK family members are pseudokinases that lack crucial residues for catalytic activity. The mutiplicity of kinases allows for specific regulation according to substrate, tissue distribution, and cellular localization. PKs regulate many cellular processes including proliferation, division, differentiation, motility, survival, metabolism, cell-cycle progression, cytoskeletal rearrangement, immunity, and neuronal functions. Many kinases are implicated in the development of various human diseases including different types of cancer. | ||
pfam07714 | Pkinase_Tyr | 5.0e-52 | 677 | 943 | 283 | + Protein tyrosine kinase. | ||
smart00219 | TyrKc | 1.0e-53 | 677 | 943 | 282 | + Tyrosine kinase, catalytic domain. Phosphotransferases. Tyrosine-specific kinase subfamily. | ||
pfam11721 | Malectin | 1.0e-53 | 408 | 595 | 190 | + Di-glucose binding within endoplasmic reticulum. Malectin is a membrane-anchored protein of the endoplasmic reticulum that recognises and binds Glc2-N-glycan. It carries a signal peptide from residues 1-26, a C-terminal transmembrane helix from residues 255-274, and a highly conserved central part of approximately 190 residues followed by an acidic, glutamate-rich region. Carbohydrate-binding is mediated by the four aromatic residues, Y67, Y89, Y116, and F117 and the aspartate at D186. NMR-based ligand-screening studies has shown binding of the protein to maltose and related oligosaccharides, on the basis of which the protein has been designated "malectin", and its endogenous ligand is found to be Glc2-high-mannose N-glycan. | ||
smart00221 | STYKc | 8.0e-54 | 677 | 943 | 282 | + Protein kinase; unclassified specificity. Phosphotransferases. The specificity of this class of kinases can not be predicted. Possible dual-specificity Ser/Thr/Tyr kinase. |
Gene Ontology | |
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GO Term | Description |
GO:0004672 | protein kinase activity |
GO:0005515 | protein binding |
GO:0005524 | ATP binding |
GO:0006468 | protein phosphorylation |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAC50043.1 | 0 | 9 | 1011 | 20 | 1019 | receptor-like serine/threonine kinase [Arabidopsis thaliana] |
GenBank | AAG50773.1 | 0 | 111 | 1011 | 1 | 900 | AC079288_2 receptor-like serine/threonine kinase, putative, 5' partial [Arabidopsis thaliana] |
RefSeq | NP_174268.7 | 0 | 9 | 1011 | 20 | 1020 | RKF1 (RECEPTOR-LIKE KINASE IN FLOWERS 1); ATP binding / kinase/ protein serine/threonine kinase/ receptor signaling protein serine/threonine kinase [Arabidopsis thaliana] |
RefSeq | NP_850955.5 | 0 | 37 | 1011 | 32 | 1005 | RKF1 (RECEPTOR-LIKE KINASE IN FLOWERS 1); ATP binding / kinase/ protein serine/threonine kinase/ receptor signaling protein serine/threonine kinase [Arabidopsis thaliana] |
RefSeq | XP_002264679.1 | 0 | 36 | 1006 | 5 | 1002 | PREDICTED: hypothetical protein [Vitis vinifera] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3ulz_A | 0 | 660 | 945 | 20 | 308 | B Chain B, Structural Basis Of Gibberellin(Ga3)-Induced Della Recognition By The Gibberellin Receptor |
PDB | 3uim_A | 0 | 660 | 945 | 20 | 308 | A Chain A, Structural Basis For The Impact Of Phosphorylation On Plant Receptor- Like Kinase Bak1 Activation |
PDB | 3tl8_H | 0 | 660 | 945 | 28 | 316 | B Chain B, The Avrptob-Bak1 Complex Reveals Two Structurally Similar Kinaseinteracting Domains In A Single Type Iii Effector |
PDB | 3tl8_G | 0 | 660 | 945 | 28 | 316 | B Chain B, The Avrptob-Bak1 Complex Reveals Two Structurally Similar Kinaseinteracting Domains In A Single Type Iii Effector |
PDB | 3tl8_D | 0 | 660 | 945 | 28 | 316 | B Chain B, The Avrptob-Bak1 Complex Reveals Two Structurally Similar Kinaseinteracting Domains In A Single Type Iii Effector |