Basic Information | |
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Species | Capsella rubella |
Cazyme ID | Carubv10012467m |
Family | CBM43 |
Protein Properties | Length: 856 Molecular Weight: 93927.8 Isoelectric Point: 5.3344 |
Chromosome | Chromosome/Scaffold: 1 Start: 4083259 End: 4087698 |
Description | O-Glycosyl hydrolases family 17 protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
CBM43 | 346 | 427 | 5.4e-34 |
CIAMDGVDAKTLQAALDWACGPGRSNCSEIQPGESCYQPNNVKGHASFAFNSYYQKEGRASGSCDFKGVAMITTTDPSHGSC | |||
GH17 | 8 | 327 | 0 |
VGFNIGTDVSNMLSPTELVKFLQTQKVNHVRLYDADPELLKAFAKTKIRVIISVPNNQLLAIGSSNSTAASWIGRNVVAYYPETLITSISVGDEVLTTVP SSAPLLLPAIESLYNALVASNLHTQIKVSTPHAASIMLDTFPPSQAYFNQTWHSIMVPLLQFLSKTGSPLMMNLYPYYVYMQNKGVVPLDNCLFEPLTPS KEMVDPNTLLHYTNVLDAMVDAAYVSMKNLNVSDVVVLVTESGWPSEGDSKEPYATIDNADTYNSNLIKHIFDRTGTPMHPEMTPSVYIYELFNEDLRSP PVSEASWGLFYGNSTPVYLL |
Full Sequence |
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Protein Sequence Length: 856 Download |
EQDKDPFVGF NIGTDVSNML SPTELVKFLQ TQKVNHVRLY DADPELLKAF AKTKIRVIIS 60 VPNNQLLAIG SSNSTAASWI GRNVVAYYPE TLITSISVGD EVLTTVPSSA PLLLPAIESL 120 YNALVASNLH TQIKVSTPHA ASIMLDTFPP SQAYFNQTWH SIMVPLLQFL SKTGSPLMMN 180 LYPYYVYMQN KGVVPLDNCL FEPLTPSKEM VDPNTLLHYT NVLDAMVDAA YVSMKNLNVS 240 DVVVLVTESG WPSEGDSKEP YATIDNADTY NSNLIKHIFD RTGTPMHPEM TPSVYIYELF 300 NEDLRSPPVS EASWGLFYGN STPVYLLHVS GSGTFLANDT TNQTYCIAMD GVDAKTLQAA 360 LDWACGPGRS NCSEIQPGES CYQPNNVKGH ASFAFNSYYQ KEGRASGSCD FKGVAMITTT 420 DPSHGSCIFP GRILTTLAMS SSSPSSSWSC NKCTFLNSPS QKLNCVICLT PASIPSPSPS 480 LSVSTNDEAK WACKACTFLN TYKNSICDVC GTRSPTSSLL GFDELTDSGL DSNNPDSSVG 540 SVFFPLRRCN NKRKAMDDDV VEIGSGSVVP GGDLGVASDS GTSLSCLKIL TYNVWFREDL 600 ELKPRMRAIG HLIQLHSPHL ICFQEVTPEI YNIFRKSNWW KEYSCSVSVD VADSRGYYCM 660 LLSKLGVKSF SSKSFGNSMM GRGLSIAEVE VPGRKPLVFA TSHLESPCPG PPKWDQMFSR 720 ERVEQANEAI EILSANTNVV FGGDMNWDDK LDGKFPLADK WVDVWEVLKP GDLGFTYDTK 780 ANPMLSGNRA LQKRLDRIFC RLDDYKLGGI EMVGKEAIPG LSYVKEKKVR GDIKELELPV 840 LPSDHFGLLV TLSPK* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd08372 | EEP | 3.0e-12 | 589 | 852 | 283 | + Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily. This large superfamily includes the catalytic domain (exonuclease/endonuclease/phosphatase or EEP domain) of a diverse set of proteins including the ExoIII family of apurinic/apyrimidinic (AP) endonucleases, inositol polyphosphate 5-phosphatases (INPP5), neutral sphingomyelinases (nSMases), deadenylases (such as the vertebrate circadian-clock regulated nocturnin), bacterial cytolethal distending toxin B (CdtB), deoxyribonuclease 1 (DNase1), the endonuclease domain of the non-LTR retrotransposon LINE-1, and related domains. These diverse enzymes share a common catalytic mechanism of cleaving phosphodiester bonds; their substrates range from nucleic acids to phospholipids and perhaps proteins. | ||
pfam07983 | X8 | 6.0e-23 | 344 | 416 | 78 | + X8 domain. The X8 domain domain contains at least 6 conserved cysteine residues that presumably form three disulphide bridges. The domain is found in an Olive pollen allergen as well as at the C-terminus of several families of glycosyl hydrolases. This domain may be involved in carbohydrate binding. This domain is characteristic of GPI-anchored domains. | ||
smart00768 | X8 | 5.0e-42 | 344 | 429 | 86 | + Possibly involved in carbohydrate binding. The X8 domain, which may be involved in carbohydrate binding, is found in an Olive pollen antigen as well as at the C terminus of family 17 glycosyl hydrolases. It contains 6 conserved cysteine residues which presumably form three disulfide bridges. | ||
cd09080 | TDP2 | 4.0e-82 | 587 | 852 | 272 | + Phosphodiesterase domain of human TDP2, a 5'-tyrosyl DNA phosphodiesterase, and related domains. Human TDP2, also known as TTRAP (TRAF/TNFR-associated factors, and tumor necrosis factor receptor/TNFR-associated protein), is a 5'-tyrosyl DNA phosphodiesterase. It is required for the efficient repair of topoisomerase II-induced DNA double strand breaks. The topoisomerase is covalently linked by a phosphotyrosyl bond to the 5'-terminus of the break. TDP2 cleaves the DNA 5'-phosphodiester bond and restores 5'-phosphate termini, needed for subsequent DNA ligation, and hence repair of the break. TDP2 and 3'-tyrosyl DNA phosphodiesterase (TDP1) are complementary activities; together, they allow cells to remove trapped topoisomerase from both 3'- and 5'-DNA termini. TTRAP has been reported as being involved in apoptosis, embryonic development, and transcriptional regulation, and it may inhibit the activation of nuclear factor-kB. This family belongs to the large EEP (exonuclease/endonuclease/phosphatase) superfamily that contains functionally diverse enzymes that share a common catalytic mechanism of cleaving phosphodiester bonds. | ||
pfam00332 | Glyco_hydro_17 | 1.0e-83 | 8 | 325 | 318 | + Glycosyl hydrolases family 17. |
Gene Ontology | |
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GO Term | Description |
GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds |
GO:0005975 | carbohydrate metabolic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAC17632.1 | 0 | 1 | 423 | 37 | 459 | Similar to glucan endo-1,3-beta-D-glucosidase precursor gb |
EMBL | CBI23232.1 | 0 | 5 | 855 | 44 | 961 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002316541.1 | 0 | 20 | 431 | 1 | 412 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002332610.1 | 0 | 20 | 431 | 1 | 412 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002518468.1 | 0 | 5 | 431 | 47 | 473 | Glucan endo-1,3-beta-glucosidase precursor, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 2cyg_A | 0 | 8 | 327 | 1 | 310 | A Chain A, Crystal Structure At 1.45- Resolution Of The Major Allergen Endo-Beta-1,3-Glucanase Of Banana As A Molecular Basis For The Latex-Fruit Syndrome |
PDB | 3ur8_B | 0 | 8 | 330 | 3 | 315 | A Chain A, Crystal Structure At 1.45- Resolution Of The Major Allergen Endo-Beta-1,3-Glucanase Of Banana As A Molecular Basis For The Latex-Fruit Syndrome |
PDB | 3ur8_A | 0 | 8 | 330 | 3 | 315 | A Chain A, Crystal Structure At 1.45- Resolution Of The Major Allergen Endo-Beta-1,3-Glucanase Of Banana As A Molecular Basis For The Latex-Fruit Syndrome |
PDB | 3ur7_B | 0 | 8 | 330 | 3 | 315 | A Chain A, Higher-density Crystal Structure Of Potato Endo-1,3-beta-glucanase |
PDB | 3ur7_A | 0 | 8 | 330 | 3 | 315 | A Chain A, Higher-density Crystal Structure Of Potato Endo-1,3-beta-glucanase |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
EX133453 | 284 | 1 | 284 | 0 |
CO117695 | 268 | 157 | 424 | 0 |
EG662509 | 273 | 71 | 343 | 0 |
FG986877 | 259 | 124 | 382 | 0 |
ES913088 | 236 | 1 | 236 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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