Basic Information | |
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Species | Capsella rubella |
Cazyme ID | Carubv10016173m |
Family | GT47 |
Protein Properties | Length: 509 Molecular Weight: 58022.4 Isoelectric Point: 9.8702 |
Chromosome | Chromosome/Scaffold: 3 Start: 909867 End: 911902 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 129 | 446 | 0 |
PLKVYMYDMSPEFHFGLLGWKPDRNGVVWPDIRVSVPHHPGGLNLQHSVEYWLTLDLLFSELPEDSRSSRAAIRVKNSSEADVVFVPFFSSLSYNRFSKV NQKQKKSQDRELQENVVKYVTSQKEWKISGGKDHVIMAHHPNSMSTARHKLYPAMFVVADFGRYSPRVANVDKDIVAPYKHLVPSYVNDTSGFDGRPILL YFQGAIYRKAGGFVRQELYYLLKEEKDVHFSFGSVRNHGITKAGDGMRSSKFCLNIAGDTPSSNRLFDAIASHCIPVIISDDIELPYEDVLNYNEFCLFV RSSDALKKGFLMGLVRSI |
Full Sequence |
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Protein Sequence Length: 509 Download |
MVERSNSRSL GVIITRKSIV FLLISILTVL SWFFIFSSTN PNRVLDYISV SEPADAPLII 60 IKNSNSSPQN NVISPNPQNR GKQNREGAET EEPNDKKNRG GTETEPFIYQ NRAKTLQCIE 120 KKGSPSPTPL KVYMYDMSPE FHFGLLGWKP DRNGVVWPDI RVSVPHHPGG LNLQHSVEYW 180 LTLDLLFSEL PEDSRSSRAA IRVKNSSEAD VVFVPFFSSL SYNRFSKVNQ KQKKSQDREL 240 QENVVKYVTS QKEWKISGGK DHVIMAHHPN SMSTARHKLY PAMFVVADFG RYSPRVANVD 300 KDIVAPYKHL VPSYVNDTSG FDGRPILLYF QGAIYRKAGG FVRQELYYLL KEEKDVHFSF 360 GSVRNHGITK AGDGMRSSKF CLNIAGDTPS SNRLFDAIAS HCIPVIISDD IELPYEDVLN 420 YNEFCLFVRS SDALKKGFLM GLVRSIGREE YNKMWKRLKE VNKYFDLRFP SKEDVGDDAV 480 QMIWKAVARK APLVKMKVHR FQRFIKPF* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 8.0e-55 | 126 | 446 | 331 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAX33321.1 | 0 | 1 | 504 | 1 | 488 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
RefSeq | NP_187015.1 | 0 | 1 | 508 | 1 | 499 | EDA5 (embryo sac development arrest 5); catalytic [Arabidopsis thaliana] |
RefSeq | NP_190126.1 | 0 | 1 | 504 | 3 | 453 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002319201.1 | 0 | 1 | 504 | 3 | 449 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002530948.1 | 0 | 60 | 508 | 57 | 483 | catalytic, putative [Ricinus communis] |