y
Basic Information | |
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Species | Capsella rubella |
Cazyme ID | Carubv10017118m |
Family | GT47 |
Protein Properties | Length: 484 Molecular Weight: 55305.3 Isoelectric Point: 9.5216 |
Chromosome | Chromosome/Scaffold: 5 Start: 6638110 End: 6640261 |
Description | exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 85 | 406 | 0 |
APLKVYMYNMDPEFHFGLLDWKPDGKKKGSSSVWPDVQKFIPPYPGGLNLQHSIEYWLTLDLLASEYENAPRTVAAKRVYNSTEADVIFVPFFSSLSYNR FSKVNPHQKISKNKDLQRKLVSFLTAQEEWKRSGGRDHVVLAHHPNSMLDARNKLFPAMFILSDFGRYPPTVANVEKDIIAPYKHVIKAYENDTSGFDSR PILLYFQGAIYRKDGGFVRQELFYLLQDEKDVHFSFGSVRNGGINKASQGMHNSKFCLNIAGDTPSSNRLFDAIASHCVPVIISDDIELPFEDVLDYSEF SVFVRTADALKENFLVNLIRGI |
Full Sequence |
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Protein Sequence Length: 484 Download |
MAMVEKNGSA IGYVARNLLL CLFVVTTILF ALSCYFVLRS TAHNRFLSST FSSKSFDVNV 60 KGVKRERDDC SRCVKDDKSV IAKAAPLKVY MYNMDPEFHF GLLDWKPDGK KKGSSSVWPD 120 VQKFIPPYPG GLNLQHSIEY WLTLDLLASE YENAPRTVAA KRVYNSTEAD VIFVPFFSSL 180 SYNRFSKVNP HQKISKNKDL QRKLVSFLTA QEEWKRSGGR DHVVLAHHPN SMLDARNKLF 240 PAMFILSDFG RYPPTVANVE KDIIAPYKHV IKAYENDTSG FDSRPILLYF QGAIYRKDGG 300 FVRQELFYLL QDEKDVHFSF GSVRNGGINK ASQGMHNSKF CLNIAGDTPS SNRLFDAIAS 360 HCVPVIISDD IELPFEDVLD YSEFSVFVRT ADALKENFLV NLIRGISKEE WTRMWKRLQE 420 VEKHYEFHFP SKVDDAVQMI WQAIARKVPS VKMRIHKSRR YSGSASDTGK ESRWSSLIPR 480 SFW* 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 5.0e-57 | 85 | 406 | 332 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN68950.1 | 0 | 3 | 483 | 1 | 488 | hypothetical protein [Vitis vinifera] |
RefSeq | NP_190126.1 | 0 | 1 | 483 | 1 | 475 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002268382.1 | 0 | 3 | 483 | 1 | 488 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002319201.1 | 0 | 1 | 462 | 1 | 450 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002530948.1 | 0 | 58 | 477 | 92 | 504 | catalytic, putative [Ricinus communis] |