| Basic Information | |
|---|---|
| Species | Capsella rubella |
| Cazyme ID | Carubv10018458m |
| Family | AA3 |
| Protein Properties | Length: 582 Molecular Weight: 63749 Isoelectric Point: 7.2575 |
| Chromosome | Chromosome/Scaffold: 5 Start: 11025528 End: 11028149 |
| Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA3 | 38 | 570 | 0 |
| TIAPKLSHFDYIVIGGGTAGCALAATLSQNATILVLERGGSPYDNPTATDINNFVNTLLNITPNSWTQLFISQDGVFNSRARVLGGGTVINAGFYSRAED DFVAEAGWDSDEVEAAYEWVEKKVVFQPKVKGWQSAFRDGLLEAGVTPYNGFTYEHIYGTKIGGTIIDENGRRHTAANLLEYANPNKIAVYLHASVHKIL FTTKESPKPKAKGVIFRDANGVFHTAKLVDQDAMNEVILSAGAIASPQLLMLSGVGPRSHLAAHGVNPIILDHPMVGKGMGDNPMNPVLVLSPKPVEVSL VQIAGIPHFGSYIEGLSGLSLSISLTHSFFNGVLNLLNEIKLPTKTLSNFFKSLDFRFNVTAQAGGMVMKVYGPLSRGHLELRNTNPDDNPSVTFNYYQE PEDLNNCVKGLSALIKVIDSKGYSKYKFPGVTGRGLLDLILLLPNNLRPRHITSTFDLKQFCKDTVMTLYHYHGGCQVGKVVDNDYKVLGIDGLRVIDAS TFLKTPGTNPQATIMMLGRYMGQKILRERAASQ | |||
| Full Sequence |
|---|
| Protein Sequence Length: 582 Download |
| MEFYIFRLFC FVVVAVFIFH DSCYSDKAGY YSFMKDATIA PKLSHFDYIV IGGGTAGCAL 60 AATLSQNATI LVLERGGSPY DNPTATDINN FVNTLLNITP NSWTQLFISQ DGVFNSRARV 120 LGGGTVINAG FYSRAEDDFV AEAGWDSDEV EAAYEWVEKK VVFQPKVKGW QSAFRDGLLE 180 AGVTPYNGFT YEHIYGTKIG GTIIDENGRR HTAANLLEYA NPNKIAVYLH ASVHKILFTT 240 KESPKPKAKG VIFRDANGVF HTAKLVDQDA MNEVILSAGA IASPQLLMLS GVGPRSHLAA 300 HGVNPIILDH PMVGKGMGDN PMNPVLVLSP KPVEVSLVQI AGIPHFGSYI EGLSGLSLSI 360 SLTHSFFNGV LNLLNEIKLP TKTLSNFFKS LDFRFNVTAQ AGGMVMKVYG PLSRGHLELR 420 NTNPDDNPSV TFNYYQEPED LNNCVKGLSA LIKVIDSKGY SKYKFPGVTG RGLLDLILLL 480 PNNLRPRHIT STFDLKQFCK DTVMTLYHYH GGCQVGKVVD NDYKVLGIDG LRVIDASTFL 540 KTPGTNPQAT IMMLGRYMGQ KILRERAASQ GNEEETTKIE L* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam05199 | GMC_oxred_C | 4.0e-27 | 411 | 555 | 150 | + GMC oxidoreductase. This domain found associated with pfam00732. | ||
| TIGR01810 | betA | 4.0e-33 | 47 | 567 | 575 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
| PRK02106 | PRK02106 | 4.0e-36 | 45 | 563 | 615 | + choline dehydrogenase; Validated | ||
| COG2303 | BetA | 4.0e-37 | 45 | 570 | 581 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
| PLN02785 | PLN02785 | 0 | 26 | 566 | 549 | + Protein HOTHEAD | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAB11043.1 | 0 | 1 | 556 | 1 | 563 | mandelonitrile lyase-like protein [Arabidopsis thaliana] |
| EMBL | CAB87405.1 | 0 | 1 | 556 | 1 | 557 | ADHESION OF CALYX EDGES-like protein [Arabidopsis thaliana] |
| RefSeq | NP_001119417.1 | 0 | 34 | 566 | 1 | 543 | glucose-methanol-choline (GMC) oxidoreductase family protein [Arabidopsis thaliana] |
| RefSeq | NP_200008.1 | 0 | 1 | 575 | 1 | 585 | glucose-methanol-choline (GMC) oxidoreductase family protein [Arabidopsis thaliana] |
| RefSeq | NP_567032.1 | 0 | 1 | 576 | 1 | 577 | glucose-methanol-choline (GMC) oxidoreductase family protein [Arabidopsis thaliana] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3gdp_B | 0 | 30 | 570 | 11 | 521 | A Chain A, Pectin Methylesterase Pema From Erwinia Chrysanthemi |
| PDB | 3gdp_A | 0 | 30 | 570 | 11 | 521 | A Chain A, Pectin Methylesterase Pema From Erwinia Chrysanthemi |
| PDB | 3gdn_B | 0 | 30 | 570 | 11 | 521 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
| PDB | 3gdn_A | 0 | 30 | 570 | 11 | 521 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
| PDB | 1ju2_B | 0 | 30 | 570 | 11 | 521 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
