| Basic Information | |
|---|---|
| Species | Capsella rubella |
| Cazyme ID | Carubv10019735m |
| Family | GT20 |
| Protein Properties | Length: 945 Molecular Weight: 106130 Isoelectric Point: 7.1455 |
| Chromosome | Chromosome/Scaffold: 2 Start: 13223795 End: 13232343 |
| Description | trehalose-6-phosphate synthase |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT20 | 90 | 559 | 0 |
| YNRQRLLVVANRLPVSAVRRGEDSWSLEISAGGLVSALLGVKEFEARWIGWAGVNVPDEVGQKALSKALAEKRCIPVFLDEEIVHQYYNGYCNNILWPLF HYLGLPQEDRLATTRSFQSQFAAYKKANQMFADVVNEHYEEGDVVWCHDYHLMFLPKCLKEYNSKMKVGWFLHTPFPSSEIHRTLPSRSELLRSVLAADL VGFHTYDYARHFVSACTRILGLEGTPEGVEDQGRLTRVAAFPIGIDSERFIRALEVPEVIQHMKELKERFAGRKVMLGVDRLDMIKGIPQKILAFEKFLE ENASWRDKVVLLQIAVPTRTDVPEYQKLTSQVHEIVGRINGRFGTLTAVPIHHLDRSLDFHALCALYAVTDVALVTSLRDGMNLVSYEFVACQEAKKGVL ILSEFAGAAQSLGAGAILVNPWNITEVAASIGQALNMSAEEREKRHRHNFHHVKTHTAQEWAETFVSELN | |||
| Full Sequence |
|---|
| Protein Sequence Length: 945 Download |
| MPGNKYNCSS SHIPLSRTER LLRDRELREK RKSNRARNPN DVVGSSDNSE NDIRLEGDSS 60 TRQYVEQYLE GAAAAMAHDD ACERQEARPY NRQRLLVVAN RLPVSAVRRG EDSWSLEISA 120 GGLVSALLGV KEFEARWIGW AGVNVPDEVG QKALSKALAE KRCIPVFLDE EIVHQYYNGY 180 CNNILWPLFH YLGLPQEDRL ATTRSFQSQF AAYKKANQMF ADVVNEHYEE GDVVWCHDYH 240 LMFLPKCLKE YNSKMKVGWF LHTPFPSSEI HRTLPSRSEL LRSVLAADLV GFHTYDYARH 300 FVSACTRILG LEGTPEGVED QGRLTRVAAF PIGIDSERFI RALEVPEVIQ HMKELKERFA 360 GRKVMLGVDR LDMIKGIPQK ILAFEKFLEE NASWRDKVVL LQIAVPTRTD VPEYQKLTSQ 420 VHEIVGRING RFGTLTAVPI HHLDRSLDFH ALCALYAVTD VALVTSLRDG MNLVSYEFVA 480 CQEAKKGVLI LSEFAGAAQS LGAGAILVNP WNITEVAASI GQALNMSAEE REKRHRHNFH 540 HVKTHTAQEW AETFVSELND TVIEAQLRIS KVPPELPQND AIQRYSKSNN RLLILGFNAT 600 LTEPVDNQGR RGDQIKEMDL NLHPELKGPL KALCSDPSTT IVVLSGSSRS VLDKNFGEYD 660 MWLAAENGMF LRLTNGEWMT TMPEHLNMEW VDSVKHVFKY FTERTPRSHF ETRDTSLIWN 720 YKYADIEFGR LQARDLLQHL WTGPISNASV DVVQGSRSVE VRAVGVTKGA AIDRILGEIV 780 HSKSMTTPID YVLCIGHFLG KDEDVYTFFE PELPSDIPAI ARARPSSDSG SKSSSGDRRP 840 PPKSTHNNKS GPKSSSSSNS NNNNNKSSQR SLQTTERKSG SNHSLGNSRR PSPEKISWNV 900 LDLKGENYFS CAVGRTRTNA RYLLGSPDDV VCFLEKLADT TSSP* 960 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PLN03063 | PLN03063 | 2.0e-12 | 884 | 943 | 62 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PLN03064 | PLN03064 | 0 | 1 | 943 | 946 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PLN03063 | PLN03063 | 0 | 92 | 815 | 724 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| TIGR02400 | trehalose_OtsA | 0 | 94 | 560 | 469 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming]. This enzyme catalyzes the key, penultimate step in biosynthesis of trehalose, a compatible solute made as an osmoprotectant in some species in all three domains of life. The gene symbol OtsA stands for osmotically regulated trehalose synthesis A. Trehalose helps protect against both osmotic and thermal stresses, and is made from two glucose subunits. This model excludes glucosylglycerol-phosphate synthase, an enzyme of an analogous osmoprotectant system in many cyanobacterial strains. This model does not identify archaeal examples, as they are more divergent than glucosylglycerol-phosphate synthase. Sequences that score in the gray zone between the trusted and noise cutoffs include a number of yeast multidomain proteins in which the N-terminal domain may be functionally equivalent to this family. The gray zone also includes the OtsA of Cornyebacterium glutamicum (and related species), shown to be responsible for synthesis of only trace amounts of trehalose while the majority is synthesized by the TreYZ pathway; the significance of OtsA in this species is unclear (see Wolf, et al., PMID:12890033) [Cellular processes, Adaptations to atypical conditions]. | ||
| pfam00982 | Glyco_transf_20 | 0 | 93 | 560 | 474 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005992 | trehalose biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABO61742.1 | 0 | 1 | 943 | 1 | 922 | trehalose-phosphate synthase 1 [Solanum lycopersicum] |
| EMBL | CAA69879.1 | 0 | 1 | 944 | 1 | 942 | trehalose-6-phosphate synthase [Arabidopsis thaliana] |
| RefSeq | NP_177979.1 | 0 | 1 | 944 | 1 | 942 | ATTPS1 (TREHALOSE-6-PHOSPHATE SYNTHASE); alpha,alpha-trehalose-phosphate synthase (UDP-forming)/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
| RefSeq | XP_002331300.1 | 0 | 1 | 942 | 1 | 922 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002531237.1 | 0 | 1 | 942 | 1 | 924 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1gz5_D | 0 | 94 | 562 | 2 | 454 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_C | 0 | 94 | 562 | 2 | 454 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_B | 0 | 94 | 562 | 2 | 454 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_A | 0 | 94 | 562 | 2 | 454 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 2wtx_D | 0 | 94 | 562 | 3 | 455 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| Hydropathy |
|---|
 |
| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| ES813375 | 361 | 455 | 815 | 0 |
| CX546763 | 302 | 82 | 383 | 0 |
| CV711307 | 294 | 91 | 384 | 0 |
| DW069910 | 288 | 180 | 467 | 0 |
| CX545499 | 305 | 397 | 701 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
|---|
 |
