y
Basic Information | |
---|---|
Species | Capsella rubella |
Cazyme ID | Carubv10020028m |
Family | AA3 |
Protein Properties | Length: 593 Molecular Weight: 65222 Isoelectric Point: 10.3325 |
Chromosome | Chromosome/Scaffold: 2 Start: 11024255 End: 11027398 |
Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
View CDS |
External Links |
---|
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
AA3 | 39 | 585 | 0 |
EKASTFSSSSSSSFSSNGQDSSYDYIVIGGGTAGCPLAATLSQNFSVLVLERGGVPFTNANVSFLRNFHIGLADTSASSASQAFVSTDGVFNARARVLGG GSCINAGFYSRADDAFVKRSGWDPKLVKESYPWVERVIVHQPKLTLWQKALRDSLLEVGVRPFNGFTYDHVSGTKVGGTIFDRFGRRHTSAELLAYANPQ KLRVLIYATVQKIVFDTSGTRPRVTGVIFKDEKGNQHQALLSNRKGSEVILSSGAMGSPQMLMLSGIGPKKELQRLKIPVVLENEHVGKGMADNPMNTIL VPSKAPIEQSLIQTVGITKMGVYVEASTGFGQSPQSIHTHYGIMSDKNELFSATPAKQRRPEAAQAFIRRKKYQLHEAFNGSFILEKLAYPLSRGHLSLV NTNVDDNPSVTFNYFKHPADLQRCVEAIRLVSKVVTSKRFLNYTQCEKQDVHKMLSLSVKANINLRPKQLNDTESMAQFCKDTVVTIWHYHGGCLVGKVV SPNRRVLGVDRLRVIDGSTFHESPGTNPQATLMMMGRYMGVKILRKR |
Full Sequence |
---|
Protein Sequence Length: 593 Download |
MALKLFLFAL LLCLPTSLSS TASKEKKLKF NPYRYSFIEK ASTFSSSSSS SFSSNGQDSS 60 YDYIVIGGGT AGCPLAATLS QNFSVLVLER GGVPFTNANV SFLRNFHIGL ADTSASSASQ 120 AFVSTDGVFN ARARVLGGGS CINAGFYSRA DDAFVKRSGW DPKLVKESYP WVERVIVHQP 180 KLTLWQKALR DSLLEVGVRP FNGFTYDHVS GTKVGGTIFD RFGRRHTSAE LLAYANPQKL 240 RVLIYATVQK IVFDTSGTRP RVTGVIFKDE KGNQHQALLS NRKGSEVILS SGAMGSPQML 300 MLSGIGPKKE LQRLKIPVVL ENEHVGKGMA DNPMNTILVP SKAPIEQSLI QTVGITKMGV 360 YVEASTGFGQ SPQSIHTHYG IMSDKNELFS ATPAKQRRPE AAQAFIRRKK YQLHEAFNGS 420 FILEKLAYPL SRGHLSLVNT NVDDNPSVTF NYFKHPADLQ RCVEAIRLVS KVVTSKRFLN 480 YTQCEKQDVH KMLSLSVKAN INLRPKQLND TESMAQFCKD TVVTIWHYHG GCLVGKVVSP 540 NRRVLGVDRL RVIDGSTFHE SPGTNPQATL MMMGRYMGVK ILRKRLGDKA GV* 600 |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
TIGR03970 | Rv0697 | 1.0e-19 | 62 | 333 | 316 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
pfam05199 | GMC_oxred_C | 3.0e-28 | 429 | 574 | 151 | + GMC oxidoreductase. This domain found associated with pfam00732. | ||
TIGR01810 | betA | 8.0e-39 | 62 | 574 | 559 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
COG2303 | BetA | 1.0e-47 | 61 | 583 | 574 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
PLN02785 | PLN02785 | 0 | 61 | 592 | 532 | + Protein HOTHEAD |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
GO:0050660 | flavin adenine dinucleotide binding |
GO:0055114 | oxidation-reduction process |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAA77842.1 | 0 | 15 | 592 | 15 | 594 | ACE [Arabidopsis thaliana] |
RefSeq | NP_001154469.1 | 0 | 15 | 592 | 15 | 567 | HTH (HOTHEAD); FAD binding / aldehyde-lyase/ mandelonitrile lyase [Arabidopsis thaliana] |
RefSeq | NP_565050.1 | 0 | 15 | 592 | 15 | 594 | HTH (HOTHEAD); FAD binding / aldehyde-lyase/ mandelonitrile lyase [Arabidopsis thaliana] |
RefSeq | XP_002329018.1 | 0 | 22 | 592 | 21 | 591 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002527404.1 | 0 | 32 | 591 | 38 | 596 | glucose-methanol-choline (gmc) oxidoreductase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3gdp_B | 0 | 58 | 585 | 24 | 517 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
PDB | 3gdp_A | 0 | 58 | 585 | 24 | 517 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
PDB | 3gdn_B | 0 | 58 | 585 | 24 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 3gdn_A | 0 | 58 | 585 | 24 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 1ju2_B | 0 | 58 | 585 | 24 | 517 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |