Basic Information | |
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Species | Capsella rubella |
Cazyme ID | Carubv10020184m |
Family | GT47 |
Protein Properties | Length: 495 Molecular Weight: 57241.2 Isoelectric Point: 7.1351 |
Chromosome | Chromosome/Scaffold: 2 Start: 8569186 End: 8571535 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 113 | 426 | 0 |
PLRVFMYDLPRKFNVAMMDPRSSDVEPLTGKNLPSWPQTSGIKRQHSVEYWLMASLLQRGGDGGDDEAIRVFDPDLADAFYVPFFSSLSFNTHGKNMTDP DTEFDRKLQVELMEFLENSEYWKRSGGKDHVIPMTHPNAFRFLRQQVNASILIVVDFGRYPKDMARLSKDVVSPYVHVVETLTEDGDDDGMTDPFEARTT LLYFRGNTARKDEGKIRLRLEKLLANNSDVHYEKSVATTQNIKVSTEGMRSSKFCLHPAGDTPSSCRLFDAIVSHCIPVIISDKIELPFEDEIDYSEFSV FFSIKESLEPGYIL |
Full Sequence |
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Protein Sequence Length: 495 Download |
MNRITLFVCQ SLNTFRFNQN SLEEASKQQT TNTKQRPLDP NLTFFSFSFS ISLSPSLSPE 60 EEMYGKTICT IVFFIFLVAS FSIYMGTVDP RPYFYLLQSQ PREASPCSSN GRPLRVFMYD 120 LPRKFNVAMM DPRSSDVEPL TGKNLPSWPQ TSGIKRQHSV EYWLMASLLQ RGGDGGDDEA 180 IRVFDPDLAD AFYVPFFSSL SFNTHGKNMT DPDTEFDRKL QVELMEFLEN SEYWKRSGGK 240 DHVIPMTHPN AFRFLRQQVN ASILIVVDFG RYPKDMARLS KDVVSPYVHV VETLTEDGDD 300 DGMTDPFEAR TTLLYFRGNT ARKDEGKIRL RLEKLLANNS DVHYEKSVAT TQNIKVSTEG 360 MRSSKFCLHP AGDTPSSCRL FDAIVSHCIP VIISDKIELP FEDEIDYSEF SVFFSIKESL 420 EPGYILNNLR QFPKDKWLEM WKRLKNVSHH FEFQYPPKRE DAVNMLWRQV KHKIPNVKLA 480 VHRNRRLKVP DWWL* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-79 | 112 | 432 | 328 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAC18793.1 | 0 | 63 | 474 | 1 | 440 | End is cut off [Arabidopsis thaliana] |
RefSeq | NP_176908.2 | 0 | 63 | 494 | 1 | 430 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002272591.1 | 0 | 89 | 493 | 27 | 426 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002311068.1 | 0 | 113 | 493 | 1 | 380 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002512333.1 | 0 | 63 | 493 | 1 | 431 | catalytic, putative [Ricinus communis] |