Basic Information | |
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Species | Capsella rubella |
Cazyme ID | Carubv10020282m |
Family | GT47 |
Protein Properties | Length: 455 Molecular Weight: 52015.4 Isoelectric Point: 9.3963 |
Chromosome | Chromosome/Scaffold: 2 Start: 11639055 End: 11642715 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 70 | 387 | 0 |
LKVFMYDLPSEFHFGILNWHSKGSEIWPDVENISLVPSYPGGLNRQHSVEYWLTLDLLASEKPEINRPCSAVRVKNSIEADIVFVPFFASLSYNRKSKLR GNETVSVDRLLQERLVEYLKSQDEWKRFDGKDHLITAHHPNSLLYARNFLGSAMFVLSDFGRYPSAIASLEKDIIAPYLHVVKTISNNESAPFEKRPILA YFQGAIYRKDGGTIRQELYNLLKDEKDVHFAFGTVRGNGTKQTGKGMASSKFCLNIAGDTPSSNRLFDAIVSHCVPVIISDQIELPFEDTLDYSSFSVFV HSSEAVKKGLLVNLLRGI |
Full Sequence |
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Protein Sequence Length: 455 Download |
MSEKSLLSSK FLFYTITVST LLFIVSSLFF LQRNESSFTS SLVRKLMTPP IKNEDLGKID 60 TKCDRNRGVL KVFMYDLPSE FHFGILNWHS KGSEIWPDVE NISLVPSYPG GLNRQHSVEY 120 WLTLDLLASE KPEINRPCSA VRVKNSIEAD IVFVPFFASL SYNRKSKLRG NETVSVDRLL 180 QERLVEYLKS QDEWKRFDGK DHLITAHHPN SLLYARNFLG SAMFVLSDFG RYPSAIASLE 240 KDIIAPYLHV VKTISNNESA PFEKRPILAY FQGAIYRKDG GTIRQELYNL LKDEKDVHFA 300 FGTVRGNGTK QTGKGMASSK FCLNIAGDTP SSNRLFDAIV SHCVPVIISD QIELPFEDTL 360 DYSSFSVFVH SSEAVKKGLL VNLLRGIRED QWRKKWERLK EVVGCFEYRF PSRPGDSVDM 420 IWSAVSHKLS SLQFDVHRKN RYRKSEIFDR SRSN* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-59 | 70 | 387 | 327 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAD55303.1 | 0 | 1 | 454 | 1 | 458 | AC008263_34 F25A4.34 [Arabidopsis thaliana] |
RefSeq | NP_565089.1 | 0 | 1 | 454 | 4 | 461 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002284930.1 | 0 | 1 | 448 | 1 | 451 | PREDICTED: hypothetical protein isoform 1 [Vitis vinifera] |
RefSeq | XP_002284932.1 | 0 | 52 | 448 | 15 | 412 | PREDICTED: hypothetical protein isoform 2 [Vitis vinifera] |
RefSeq | XP_002514760.1 | 0 | 59 | 447 | 101 | 489 | catalytic, putative [Ricinus communis] |