| Basic Information | |
|---|---|
| Species | Capsella rubella |
| Cazyme ID | Carubv10020285m |
| Family | GT47 |
| Protein Properties | Length: 454 Molecular Weight: 52565.4 Isoelectric Point: 8.6972 |
| Chromosome | Chromosome/Scaffold: 2 Start: 9057280 End: 9059022 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 66 | 399 | 0 |
| QNFTVYVYDLPKEFNIGLLQNCRHLNIYTNMCPHVSNNGLGQPLHRGGRTSWFATHQFIAEMIFHARVENHPCRTWNPHNADIFYVPFYGGLYASSVFRE QNLTKRDELAVRLVDYISGQRWWRRSNGRDHFLAIGRTAWDFMRSPDTDFGANILMQMPRVMNMSVLTVERQPWKGDNHFGIPYPSYFHPYTSAEMVTWQ DKMRRVERPNLFSFVGGPRKGLEKAAIRDELIRQCADSSHCELLKCENGGSRCHDPMNVLGVMTRSRFCLQAPGDSFTRRSTFDSMLAGCIPVFFSPHTM YTQYMWYLPDDKRSYSVFMDEINSTQIEQELLSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 454 Download |
| MRQVKIDLWL EKKEDKEKEK YPKNKKHNKL IHLTLLISST VCFLFLILHF PITTEFKVSL 60 PRKCNQNFTV YVYDLPKEFN IGLLQNCRHL NIYTNMCPHV SNNGLGQPLH RGGRTSWFAT 120 HQFIAEMIFH ARVENHPCRT WNPHNADIFY VPFYGGLYAS SVFREQNLTK RDELAVRLVD 180 YISGQRWWRR SNGRDHFLAI GRTAWDFMRS PDTDFGANIL MQMPRVMNMS VLTVERQPWK 240 GDNHFGIPYP SYFHPYTSAE MVTWQDKMRR VERPNLFSFV GGPRKGLEKA AIRDELIRQC 300 ADSSHCELLK CENGGSRCHD PMNVLGVMTR SRFCLQAPGD SFTRRSTFDS MLAGCIPVFF 360 SPHTMYTQYM WYLPDDKRSY SVFMDEINST QIEQELLSIS DSEVARMRET VIGLVPSMTY 420 AHPNATNYDL PDAVDVALEA LAKQARAKAM VSL* |
| Functional Domains Download unfiltered results here | ||||||
|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
| pfam03016 | Exostosin | 3.0e-77 | 68 | 399 | 346 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAC42883.1 | 0 | 2 | 453 | 6 | 455 | unknown protein [Arabidopsis thaliana] |
| RefSeq | NP_177014.1 | 0 | 2 | 453 | 6 | 455 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002270383.1 | 0 | 70 | 448 | 125 | 502 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002300452.1 | 0 | 64 | 441 | 1 | 391 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002336132.1 | 0 | 54 | 441 | 12 | 412 | predicted protein [Populus trichocarpa] |
