| Basic Information | |
|---|---|
| Species | Capsella rubella |
| Cazyme ID | Carubv10022452m |
| Family | GT24 |
| Protein Properties | Length: 1604 Molecular Weight: 181258 Isoelectric Point: 5.4001 |
| Chromosome | Chromosome/Scaffold: 2 Start: 10372961 End: 10383013 |
| Description | UDP-glucose:glycoprotein glucosyltransferases;transferases, transferring hexosyl groups;transferases, transferring glycosyl groups |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT24 | 1292 | 1539 | 0 |
| INIFSIASGHLYERFLKIMILSVLKNTNRPVKFWFIKNYLSPQFKDVIPHMAQEYNFEYELITYKWPSWLHKQKEKQRIIWAYKILFLDVIFPLSLEKVI FVDADQIIRTDMGELYDMDIKGRPLAYTPFCDNNREMDGYRFWRQGFWKEHLRGRPYHISALYVVDLVTFRETAAGDNLRVFYETLSKDPNSLSNLDQDL PNYAQHTVPIFSLPQEWLWCESWCGNATKSKARTIDLCNNPMTKEPKL | |||
| Full Sequence |
|---|
| Protein Sequence Length: 1604 Download |
| MGTNLRSWLY LILLFFVVVG VNAQNRRPKN VQVAVKAKWQ GTPLLLEAGE LISKESKQLF 60 WEFTDAWLGS DGDDTGDSDC KSARDCLLKI SKQASTLLAQ PVASLFHFSL TLRSASPRLV 120 LYRQLADESL SSFPHGDDPS ATDCCWVDTG SSLFYDVADL QSWLASSPAA GDAVQGPELF 180 DFDHVHFDSR AGSPVAVLYG AVGTDCFRKF HLSLAKAARE GKVTYVVRPV LPLGCEGKTR 240 PCGAIGARDN VSLAGYGVEL ALKNMEYKAM DDSAIKKGIT LEDPRTEDLS QDVRGFIFSK 300 ILDRKPELRS EVMAFRDYLL SSTVSDTLDV WELKDLGHQT AQRIVHASDP LQSMQEINQN 360 FPSVVSSLSR MKLNESIKDE ILSNQRMVPP GKALLALNGA LLNIEDMDLY MLMDLAHQEL 420 SLANHFSKLK IPDGAIRKLL LTTPLPEPDS YRVDFRSVHV NYLNNLEEDD MYKRWRSNIN 480 EILMPAFPGQ LRYIRKNLFH AVYVIDPATA CGLESIGTLR SLYENQLPVR FGVILYSTQL 540 IKTIEENGGQ IPSSNSQVIR LFLYIEEHHG IQTAFQFLGN VNRLRTESAD SSEEDIIEQD 600 YVDGAFVETI LPKVKSPPQD ILLKLQQEHT LKEASEASSM FVFKLGLAKL KCSFLMNGLV 660 FDSIEEETLL NAMNDELPKI QEQVYYGQIE SRTNVLDKLL SESGLSRYNP QIISGGKNKP 720 RFVSLASSTR KGESMLNDLN YLHSPETSDE VKYVTHLLAV DVATKKGIKL LHEGVRYLIG 780 GSKSARLGVL FSSSQNADSN SLLFIKFFEK TASSFSHKEK VLYFLDKLCS FYEREYLFKT 840 SVDSASSQIF IDKVLELAEE YGLSSKAYRS CTAESLNEEL LKRLAKVAKF LSWELGLESD 900 ANAIISNGRV IFPVDERTFL GQDLHLLESM EFNQRVKPVQ EIIEGIEWQD VDPDLLTSKY 960 FSDVFMFVSS AMATRDRSSE SARFEVLSSE YSAVLLGNEN ATIHIDAVID PLSPTGQKLA 1020 SLLQVLQKHV QTSMRIVLNP MSSLVDIPLK NYYRYVLPNM DDYSSTDFDV DGPKAFFANM 1080 PLSKTLTMNL DVPEPWLVEP VIAIHDLDNI LLENLGDTTT LQAVFEVESL VLTGHCAEKD 1140 HEAPRGLQLI LGTKNRPHLV DTLVMANLGY WQMKVSPGVW YLQLAPGRSS ELYVLQEGSD 1200 GSQDRSSLKR ITIDDLRGKV VHLEVVKRKG KEHEKLLVPS DGDDGVQQKH ERRSWNSNFL 1260 KWASGFVGGR QQSMKGTSEK EHEKGGRQGK TINIFSIASG HLYERFLKIM ILSVLKNTNR 1320 PVKFWFIKNY LSPQFKDVIP HMAQEYNFEY ELITYKWPSW LHKQKEKQRI IWAYKILFLD 1380 VIFPLSLEKV IFVDADQIIR TDMGELYDMD IKGRPLAYTP FCDNNREMDG YRFWRQGFWK 1440 EHLRGRPYHI SALYVVDLVT FRETAAGDNL RVFYETLSKD PNSLSNLDQD LPNYAQHTVP 1500 IFSLPQEWLW CESWCGNATK SKARTIDLCN NPMTKEPKLQ GARRIVTEWP DLDLEARKFT 1560 AKILGEDMEL NEPPVAAATD KPNPPPSNEV EDSEQDLESK DEL* 1620 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam01501 | Glyco_transf_8 | 0.0002 | 1296 | 1491 | 206 | + Glycosyl transferase family 8. This family includes enzymes that transfer sugar residues to donor molecules. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. This family includes Lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, and glycogenin glucosyltransferase. | ||
| cd04194 | GT8_A4GalT_like | 4.0e-14 | 1292 | 1508 | 227 | + A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS. | ||
| cd00505 | Glyco_transf_8 | 2.0e-56 | 1292 | 1539 | 257 | + Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis and glycogen synthesis. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. GT-8 comprises enzymes with a number of known activities: lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase, and N-acetylglucosaminyltransferase. GT-8 enzymes contains a conserved DXD motif which is essential in the coordination of a catalytic divalent cation, most commonly Mn2+. | ||
| pfam06427 | UDP-g_GGTase | 4.0e-82 | 962 | 1167 | 212 | + UDP-glucose:Glycoprotein Glucosyltransferase. The N-terminal region of this group of proteins is required for correct folding of the ER UDP-Glc: glucosyltransferase. | ||
| cd06432 | GT8_HUGT1_C_like | 2.0e-176 | 1292 | 1539 | 248 | + The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family. C-terminal domain of glycoprotein glucosyltransferase (UGT). UGT is a large glycoprotein whose C-terminus contains the catalytic activity. This catalytic C-terminal domain is highly homologous to Glycosyltransferase Family 8 (GT 8) and contains the DXD motif that coordinates donor sugar binding, characteristic for Family 8 glycosyltransferases. GT 8 proteins are retaining enzymes based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. The non-catalytic N-terminal portion of the human UTG1 (HUGT1) has been shown to monitor the protein folding status and activate its glucosyltransferase activity. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003980 | UDP-glucose:glycoprotein glucosyltransferase activity |
| GO:0006486 | protein glycosylation |
| GO:0016757 | transferase activity, transferring glycosyl groups |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAG51883.1 | 0 | 3 | 1603 | 5 | 1674 | AC016162_4 putative UDP-glucose:glycoprotein glucosyltransferase; 101200-91134 [Arabidopsis thaliana] |
| DDBJ | BAD28382.1 | 0 | 26 | 1596 | 35 | 1624 | putative UDP-glucose:glycoprotein glucosyltransferase [Oryza sativa Japonica Group] |
| RefSeq | NP_177278.3 | 0 | 3 | 1603 | 5 | 1613 | EBS1 (EMS-mutagenized bri1 suppressor 1); UDP-glucose:glycoprotein glucosyltransferase/ transferase, transferring glycosyl groups / transferase, transferring hexosyl groups [Arabidopsis thaliana] |
| RefSeq | XP_002268972.1 | 0 | 1 | 1603 | 1 | 1611 | PREDICTED: similar to EBS1 (EMS-MUTAGENIZED BRI1 SUPPRESSOR 1); UDP-glucose:glycoprotein glucosyltransferase/ transferase, transferring glycosyl groups / transferase, transferring hexosyl groups [Vitis vinifera] |
| RefSeq | XP_002529534.1 | 0 | 1 | 1489 | 1 | 1499 | UDP-glucose glycoprotein:glucosyltransferase, putative [Ricinus communis] |
